Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II and IX with some 1,3,4-oxadiazole- and 1,2,4-triazole-thiols

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 23, Issue 1, 2008, Pages 101-107

  Almajan, Gabriela Laura ^a   Barbuceanu, Stefania Felicia ^a   Innocenti, Alessio ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

CAI; CAII; CAIX; Carbonic anhydrase; Inhibition tumour associated; Oxadiazolethiols; Triazolethiols

Indexed keywords

4 (4 HALOGENO PHENYLSULFONYL)BENZOIC ACID HYDRAZIDE DERIVATIVE; 5 (4 PHENYLSULFONYL)PHENYL 3 (MORPHOLIN 4 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 (4 PHENYLSULFONYL)PHENYL 3 (PIPERIDIN 1 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 [4 (4 BROMOPHENYLSULFONYL)PHENYL] 3 (MORPHOLIN 4 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 [4 (4 BROMOPHENYLSULFONYL)PHENYL] 3 (PIPERIDIN 1 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 [4 (4 CHLOROPHENYLSULFONYL)PHENYL] 3 (MORPHOLIN 4 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 [4 (4 CHLOROPHENYLSULFONYL)PHENYL] 3 (PIPERIDIN 1 YL METHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; BENZOIC ACID DERIVATIVE; CARBON DISULFIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; ENZYME INHIBITOR; HETEROCYCLIC COMPOUND; HYDRAZIDE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; MERCAPTO 1,2,4 TRIAZOLE DERIVATIVE; MERCAPTO 1,3,4 OXADIAZOLE DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYTOSOL; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ANALYSIS; ENZYME INHIBITION; PRIORITY JOURNAL;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE III; CARBONIC ANHYDRASE INHIBITORS; KINETICS; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; TRIAZOLES;

EID: 39349109068     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701342417     Document Type: Article

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