Synthesis and biological activities of some new 3H-quinazolin-4-one derivatives derived from 3-phenylamino-2-thioxo-3H-quinazolin-4-one

Phosphorus, Sulfur and Silicon and the Related Elements

Volumn 179, Issue 2, 2004, Pages 411-426

  Saleh, Mohamed A ^a,b   Hafez, Yehia A ^a   Abdel Hay, Foad E ^a   Gad, Wagdy I ^a  

^a TANTA UNIVERSITY   (Egypt)

^b Tanta University   (Egypt)

Author keywords

3 Phenylamino 2 thioxo 3H quinazolin 4 one; Alkylation; Antimicrobial activity; Hydrazide; Pyrazole, pyrazolone and oxadiazole derivatives; S glycosides

Indexed keywords

(4 OXO 3 PHENYLAMINO 3,4 DIHYDROQUINAZOLIN 2 YLTHIO)ACETIC ACID HYDRAZIDE; (4 OXO 3 PHENYLAMINO 3H QUINAZOLIN 2 YLTHIO)ACETIC ACID ETHYL ESTER; 2 (4 OXO 3 PHENYLAMINO 3,4 DIHYDROQUINAZOLIN 2 YLTHIO) 1,3 DIPHENYLPROPANE 1,3 DIONE; 2 METHYLTHIO 3 PHENYLAMINO 3H QUINAZOLIN 4 ONE; 2 [2 (3 METHYL 5 OXO 4,5 DIHYDROPYRAZOL 1 YL) 2 OXOETHYLTHIO] 3 PHENYLAMINO 3H QUINAZOLIN 4 ONE; 2 [2 (3,5 DIPHENYLPYRAZOL 1 YL) 2 OXOETHYLTHIO] 3 PHENYLAMINO 3H QUINAZOLIN 4 ONE; 2 [2 (5 METHYL 3 PHENYLPYRAZOL 1 YL) 2 OXOETHYLTHIO] 3 PHENYLAMINO 3H QUINAZOLIN 4 ONE; 3 PHENYLAMINO 2 (2',3',4' TRIS O ACETYL BETA DEXTRO XYLOPYRANOSYLTHIO) 3H QUINAZOLIN 4 ONE; 3 PHENYLAMINO 2 (2',3',4',6' TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLSULFONYL) 3H QUINAZOLIN 4 ONE; 3 PHENYLAMINO 2 (2',3',4',6' TETRA O ACETYL BETA DEXTRO GLUCOPYRANOSYLTHIO) 3H QUINAZOLIN 4 ONE; 3 PHENYLAMINO 2 (5 THIOXO 4,5 DIHYDRO[1,3,4]OXADIAZOL 2 YLMETHYLTHIO) 3H QUINAZOLIN 4 ONE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL PROCEDURES; CHEMICAL REACTION; DRUG SCREENING; DRUG SYNTHESIS; HEAT TREATMENT;

EID: 1442359809     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426500490262559     Document Type: Article

References (21)

1. C. Parkanyi and D. Duran, J. Heterocycl., Chem., 37, 725 (2000).
2. G. Honda, M. Tabata, and M. Tsuda, Planta Med., 37, 172 (1979).
3. R. K. Saksena and M. Amin Khan, Ind. J. Chem., 28B, 443 (1989).
4. S. Johne, Pharamazie, 36, 583 (1981).
5. M. J. Kornet, Eur. J. Med. Chem., 21, 529 (1986).
6. A. M. Mahmoud, H. A. H. El-Sherief, G. M. El-Naggar, and A. E. Abdel-Rahman, Ind. J. Chem., 22B, 491 (1983).
7. P. Mitta and A. S. Mittra, Acta Cienc. Indica, [Ser] Chem., 9, 109 (1983); Chem. Abstr., 101, 90813 (1984).
8. P. Mitta and A. S. Mittra, Acta Cienc. Indica, [Ser] Chem., 9, 109 (1983); Chem. Abstr., 101, 90813 (1984).
9. K. R. Agarwal, S. R. Nautiyal, and D. D. Mukerji, Ind. Drugs, 23, 458 (1986); Chem. Abstr., 105, 54126 (1986).
10. K. R. Agarwal, S. R. Nautiyal, and D. D. Mukerji, Ind. Drugs, 23, 458 (1986); Chem. Abstr., 105, 54126 (1986).
11. I. Mir and M. T. Siddqui, Tetrahedron, 26, 5235 (1970).
12. Y. Hamoda, T. Matsuno, T. I. Shii, K. Imai, and M. Mano, Jap. Patent, 7563119 (1975).
13. R. M. De Marinis, J. R. E. Hoover, G. L. Dunn, P. Actor, J. V. Uri, and J. A. Weisbach, J. Antibiot., 28, 463 (1975).
14. F. Russo, G. Romeo, S. Guccione, et al., Pharmazie, 45, 242 (1990).
15. M. F. Abdel-Megeed, M. A. Saleh, Y. L. Aly, and I. M. Abdo, Nucleos. & Nucleot., 14, 1985 (1995).
16. A. Santagati, J. Longmore, S. Guccione, et al., Eur. J. Med. Chem., 32, 937 (1997).
17. M. A. Saleh, Sulfur Lett., 23(6), 265 (2000).
18. M. A. Saleh, Sulfur Lett., 25(6), 235 (2002)
19. J. Fischer Petriodou and E. P. Papdopoulos, J. Heterocycl. Chem., 19, 123 (1982).
20. U. S. P. XXII, United States Pharmacopeial Convention, Inc., Rockville, MD 20852, 1493 (1990).
21. H. K. Gakhar, S. C. Gupta, and N. Kumar, Ind. J. Chem., 20B, 14 (1981).