Novel 5-(2-hydroxyphenyl)-3-substituted-2,3-dihydro-1,3,4-oxadiazole-2- thione derivatives: Promising anticancer agents

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 4, 2006, Pages 1236-1246

  Aboraia, Ahmed S ^a   Abdel Rahman, Hamdy M ^a   Mahfouz, Nadia M ^a   El Gendy, Mahmoud A ^a  

^a Assiut University   (Egypt)

Author keywords

1,3,4 Oxadiazoles; Anticancer activity; Mannich bases; Salicylate analogs

Indexed keywords

1 [4 [[5 (2 HYDROXYPHENYL) 2 THIOXO 2,3 DIHYDRO 1,3,4 OXADIAZOL 3 YL]METHYL AMINO]PHENYL] 1 ETHANONE; 2 [[5 (2 HYDROXYPHENYL) 2 THIOXO 2,3 DIHYDRO 1,3,4 OXADIAZOL 3 YL]METHYL AMINO]BENZOIC ACID; 2 HYDROXY 4 [[5 (2 HYDROXYPHENYL) 2 THIOXO 2,3 DIHYDRO 1,3,4 OXADIAZOL 3 YL]METHYLAMINO]BENZOIC ACID; 3 [(2 CHLOROANILINO)METHYL] 5 (2 HYDROXYPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE 2 THIONE; 3 [(3 CHLOROANILINO)METHYL] 5 (2 HYDROXYPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE 2 THIONE; 3 [(4 CHLOROANILINO)METHYL] 5 (2 HYDROXYPHENYL) 2,3 DIHYDRO 1,3,4 OXADIAZOLE 2 THIONE; 4 [[5 (2 HYDROXYPHENYL) 2 THIOXO 2,3 DIHYDRO 1,3,4 OXADIAZOL 3 YL]METHYL AMINO]BENZOIC ACID; CYCLOPHOSPHAMIDE; FLUOROURACIL; OXADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; HYDROXYLATION; MOLECULAR STRUCTURE; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; THIONES;

EID: 30344436995     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.09.053     Document Type: Article

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