The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: A balancing act

Current Diabetes Reviews

Volumn 8, Issue 4, 2012, Pages 303-315

  Wiseman, Dean A ^a   Thurmond, Debbie C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Exocytosis; Insulin; Islet; Nitration; Oxidative stress; Post translational modification; S nitrosylation; SNARE protein

Indexed keywords

ANGIOTENSIN RECEPTOR; BETA ARRESTIN 2; CALCIUM ION; CYCLIC GMP; CYSTEINE; GLUCOKINASE; GLUCOSE; GUANYLATE CYCLASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MUSCARINIC M2 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; PEROXYNITRITE; POTASSIUM ION; PROTEIN C JUN; PROTEIN KINASE B; REACTIVE NITROGEN SPECIES; RYANODINE RECEPTOR; SNARE PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN; SYNTAXIN 1A; SYNTAXIN 4; TRANSITION ELEMENT; TYROSINE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; COMPLEX FORMATION; CYTOTOXICITY; DIABETES MELLITUS; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; EXOCYTOSIS; GLUCOSE TRANSPORT; GLYCOLYSIS; GRANULE CELL; HUMAN; INSULIN RELEASE; INTRACELLULAR SIGNALING; INTRACELLULAR SPACE; LIPID OXIDATION; LIPID PEROXIDATION; NITRATION; NITROSYLATION; NONHUMAN; ONCOGENE SRC; OXIDATION REDUCTION STATE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

APOPTOSIS; CYCLIC GMP; CYSTEINE; DIABETES MELLITUS; EXOCYTOSIS; FEMALE; HUMANS; INSULIN-SECRETING CELLS; MALE; NITRIC OXIDE; OXIDATION-REDUCTION; PEROXYNITROUS ACID; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84862612804     PISSN: 15733998     EISSN: 18756417     Source Type: Journal    
DOI: 10.2174/157339912800840514     Document Type: Article

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