Endothelial nitric oxide production and insulin sensitivity: A physiological link with implications for pathogenesis of cardiovascular disease

Circulation

Volumn 93, Issue 7, 1996, Pages 1331-1333

  Petrie, John R ^a   Ueda, Shinichiro ^a   Webb, David J ^b   Elliott, Henry L ^a   Connell, John M C ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

blood flows; diabetes mellitus; endothelium derived factors; hypertension; insulin

Indexed keywords

INSULIN; NITRIC OXIDE;

ADULT; ARTICLE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CORONARY ARTERY BLOOD FLOW; DIABETES MELLITUS; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0030000582     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.93.7.1331     Document Type: Article

References (10)

1. Reaven G. Role of insulin in human disease. Diabetes. 1988;37: 1595-1607.
2. Ferrannini E, Buzzicoli G, Bonadonna R, Giorico MA, Oleggini M, Graziadei L, Pedrinelli R, Brandi L, Bevilqacqua S. Insulin resistance in essential hypertension. N Engl J Med. 1987;317: 350-357.
3. Hollenbeck C, Reaven GM. Variations in insulin-stimulated glucose uptake in healthy individuals with normal glucose tolerance. J Clin Endocrinol Metab. 1987;64:1169-1173.
4. Baron AD. Cardiovascular actions of insulin in humans: implications for insulin sensitivity and vascular tone. Baillieres Clin Endocrinol Melab. 1993;7:961-987.
5. Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P. Nitric oxide accounts for insulin's vascular effects in humans. J Clin Invest. 1994;94:2511-2515.
6. G-monomethyl-L-arginine in patients with essential hypertension: the nitric oxide dilator system appears abnormal. J Hypertens. 1992; 10:1025-1031.
7. Sallis JF, Haskell WL, Wood PD, Fortmann SP, Rogers T, Blair S, Paffenbarger RS. Physical activity assessment methodology in the five-city project. Am J Epidemiol. 1985;121:91-106.
8. DeFronzo RA, Tobin J, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979;237:E214-E223.
9. Benjamin N, Calver A, Collier J, Robinson B, Vallance P, Webb D. Measuring forearm blood-flow and interpreting the responses to drugs and mediators. Hypertension. 1995;25:918-923.
10. Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measures in medical research. Br Med J. 1990;300:230-235.