Interaction of the islet nitric oxide system with L-arginine-induced secretion of insulin and glucagon in mice

British Journal of Pharmacology

Volumn 119, Issue 4, 1996, Pages 758-764

  Åkesson, Björn ^a   Mosén, Henrik ^a   Panagiotidis, Georgios ^a   Lundquist, Ingmar ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

D arginine; Glucagon secretion; Insulin secretion; L arginine; N(G) nitro L arginine methyl ester; Nitric oxide synthase inhibition; Starvation

Indexed keywords

ARGININE; GLUCAGON; GLUCOSE; INSULIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GLUCAGON RELEASE; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; STARVATION; STEREOSPECIFICITY;

EID: 0029917362     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15737.x     Document Type: Article

References (32)

1. AHREN, B. & LUNDQUIST, I. (1982). Glucagon immunoreactivity in plasma from normal and dystrophic mice. Diabetologia, 22, 258-263.
2. + channels. Biochim. Biophys. Acta, 1175, 293-301.
3. BOUWENS, L. & KLÖPPEL, G. (1994). Cytochemical localization of NADPH-diaphorase in the four types of pancreatic islet cell. Histochemistry, 101, 209-214.
4. BRUSS, M.L. & BLACK, A.L. (1978). Enzymatic microdetermination of glycogen. Anal. Biochem., 84, 309-312.
5. CORBETT, J.A., WANG, J.L., MISKO, T.P., ZHAO, W., HICKEY, W.F. & MCDANIEL, M.L. (1993). Nitric oxide mediates IL-1ß-induced islet dysfunction and destruction: Prevention by dexamethasone. Autoimmunity, 15, 145-153.
6. CUNNINGHAM, J.M., MABELY, J.G., DELANEY, C.A. & GREEN, I.C. (1994). The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting cell lines HIT-T15 and RINm5F. Mol. Cell. Endocrinol. 102, 23-29.
7. FÖRSTERMAN, U., SCHMIDT, H.H.H.W., POLLOCK, J.S., SHENG, H., MITCHELL, J.A., WARNER, T.D., NAKANE, M. & MURAD, F. (1991). Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem. Pharmacol, 42, 1849-1857.
8. GOTOH, M., MAKI, T., KIYOIZUMI, T., SATOMI, S. & MONACO, A.P. (1985). An improved method for isolation of mouse pancreatic islets. Transplantation, 40, 437-438.
9. ω-nitro-L-arginine methyl ester. Br. J. Pharmacol., 116, 1965-1972.
10. HEDESKOV, C.J. (1980). Mechanism of glucose-induced insulin secretion. Physiol. Rev., 60, 442-509.
11. HEDING, L. (1966). A simplified insulin radioimmunoassay method. In Labelled Proteins in Tracer Studies, ed. Donato, L., Milhaud, G. & Sirchis, J. pp. 345-350. Brussels: Euratom.
12. 2+ in the release of pancreatic islet hormones. Diabète Metab., 20, 123-131.
13. G-nitro L-arginine stimulates pancreatic islet insulin release in vitro, but not in the perfused pancreas. Endocrinology, 128, 3081-3085.
14. JONES, P.M., PERSAUD, S.J., BJAALAND, T., PEARSON, J.D & HOWELL, S.L. (1992). Nitric oxide is not involved in the initiation of insulin secretion from rat islets of Langerhans. Diabetologia, 35, 1020-1027.
15. KNOWLES, R.G. & MONCADA, S. (1994). Nitric oxide synthases in mammals. Biochem. J., 298, 249-258.
16. LAYCHOCK, R.G., MODICA, M.E. & CAVANAUGH, C.T. (1991). L-Arginine stimulates cyclic guanosine 3′,5′-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine: nitric oxide synthase. Endocrinology, 129, 3043-3052.
17. LUNDQUIST, I. (1986). Islet amyloglucosidase activity: some characteristics, and its relation to insulin secretion stimulated by various secretagogues. Diabetes Res., 3, 31-41.
18. LUNDQUIST, I., FANSKA, R. & GRODSKY, G.M. (1976). Direct calcium-stimulated release of glucagon from the isolated perfused rat pancreas and the effect of chemical sympathectomy. Endocrinology, 98, 815-818.
19. LUNDQUIST, I. & LÖVDAHL, R. (1983). Effect of fasting on islet lysosomal enzyme activities and the in vivo insulin response to different secretagogues. Horm. Metabol. Res., 15, 11-14.
20. LUNDQUIST, L, PANAGIOTIDIS, G. & STENSTRÖM, A. (1991). Effect of L-DOPA administration on islet monoamine oxidase activity and glucose-induced insulin release in the mouse. Pancreas, 6, 522-527.
21. MARUYAMA, H., HISATOMI, A., ORCI. L., GRODSKY, G.M. & UNGER, R.H. (1984). Insulin within islets is a physiologic glucagon release inhibitor. J. Clin. Invest., 74, 2296-2299.
22. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142.
23. PANAGIOTIDIS, G., ÅKESSON, B., ALM, P. & LUNDQUIST, I. (1994a). The nitric oxide system in the endocrine pancreas induces differential effects on the secretion of insulin and glucagon. Endocrine, 2, 787-792.
24. PANAGIOTIDIS, G., ÅKESSON, B., RYDELL, E.L. & LUNDQUIST, I. (1995). Influence of nitric oxide synthase inhibition, nitric oxide and hydroperoxide on insulin release induced by various secretagogues. Br. J. Pharmacol., 114, 289-296.
25. PANAGIOTIDIS, G., LINDSTRÖM, P., STENSTRÖM, A. & LUNDQUIST, I. (1993a), Glucose modulation of islet monoamine oxidase activity in lean and obese hyperglycemic mice. Metabolism, 42, 1398-1404.
26. PANAGIOTIDIS, G., SALEHI, A.A., WESTERMARK, P. & LUNDQUIST, I. (1992b). Homologous islet amyloid polypeptide: effects on plasma levels of glucagon, insulin and glucose in the mouse. Diabetes Res. Clin. Pract., 18, 167-171.
27. PANAGIOTIDIS, G., STENSTRÖM, A. & LUNDQUIST, I. (1993b). Influence of β-adenoceptor stimulation and glucose on islet monoamine oxidase activity and insulin secretory response in the mouse. Pancreas, 8, 368-374.
28. PANAGIOTIDIS, G., STENSTRÖM, A. & LUNDQUIST, I. (1993c). Effects of adrenergic and cholinergic stimulation on islet monoamine oxidase activity and insulin secretion in the mouse. Eur. J. Pharmacol., 233, 285-290.
29. PANAGIOTIDIS, G., STENSTRÖM, A. & LUNDQUIST, I. (1994b). In vivo action of cyclic AMP modulating secretagogues on islet monoamine oxidase activity and insulin release. Endocrine, 2, 571-576.
30. RERUP, C. & LUNDQUIST, I. (1966). Evaluation of a new technique of multiple serial sampling. Acta Endocrinol., 52, 357-367.
31. SANDLER, S., EIZIRIK, D.L., SVENSSON, C., STRANDELL, E., WELSH, M. & WELSH, N. (1991). Biochemical and molecular actions of interleukin-1 on pancreatic β-cells. Autoimmunity, 10, 241-253.
32. SCHMIDT, H.H.H.W., WARNER, T.D., ISHII, K., SHENG, H. & MURAD, F. (1992). Insulin secretion from pancreatic β cells caused by L-arginine-derived nitrogen oxides. Science, 255, 721-723.