Intracellular invasion of Orientia tsutsugamushi activates inflammasome in ASC-dependent manner

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Koo, Jung Eun ^a   Hong, Hye Jin ^a   Dearth, Andrea ^b   Kobayashi, Koichi S ^b,c   Koh, Young Sang ^a  

^a Jeju National University School of Medicine   (South Korea)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CRYOPYRIN; CYTOKINE; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN AIM2; PROTEIN NLRC4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INVASION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOSOME; ENZYME ACTIVATION; FEMALE; HEAT; HOST RESISTANCE; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; ORIENTIA TSUTSUGAMUSHI; PHAGOSOME; SCRUB TYPHUS; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION;

ANIMALS; CARRIER PROTEINS; CASPASE 1; CELL DEATH; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; MICE; ORIENTIA TSUTSUGAMUSHI; PHAGOCYTOSIS; PHAGOSOMES; RECEPTORS, INTERLEUKIN-1; SCRUB TYPHUS; SIGNAL TRANSDUCTION;

EID: 84862502510     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039042     Document Type: Article

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