Small molecule drug discovery at the glucagon-like peptide-1 receptor

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Willard, Francis S ^a   Bueno, Ana B ^b   Sloop, Kyle W ^a  

^a ELI LILLY AND COMPANY   (United States)

^b ELI LILLY AND COMPANY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BIS [[4 (TERT BUTOXYCARBONYLAMINO)BENZOYL]AMINO] 2,4 BIS [3 METHOXY 4 (THIOPHENE 2 CARBONYLOXY)PHENYL]CYCLOBUTANE 1,3 DICARBOXYLIC ACID]; 2 (3 METHYLQUINOXALIN 2 YL)SULFANYL N PHENYL ACETAMIDE); 2 (3,4 DIHYDROXYPHENYL) 3,5,7 TRIHYDROXY CHROMEN 4 ONE; 2 (3,4 DIHYDROXYPHENYL)CHROMANE 3,5,7 TRIOL); 2 [6,7 DICHLORO 3 (TRIFLUOROMETHYL)QUINOXALIN 2 YL]SULFANYL 5 METHY 1,3,4 THIADIAZOLE; 3 (4 BROMOPHENYL) N (4 METHOXYPHENYL) 1 PHENYL PYRAZOLE 4 CARBOXAMIDE); 3 [4 [5 [4 (TERTBUTOXYCARBONYLAMINO)PHENY] 1,2,4 OXADIAZOL 3 YL] 3 FLUORO PHENYL] 2 [[5(P TOLY)FURAN 2 CARBONYL]AMINO]PROPANOIC ACID]; 3 [[4 [[(4 TERT BUTYLCYCLOHEXYL) (PTOLYLCARBAMOYL)AMINO]METHYL]BENZOYL]AMINO]PROPANOIC ACID; 4 (3 BENZYLOXYPHENYL) 2 ETHYLSULFINYL 6 (TRIFLUOROMETHYL) PYRIMIDINE; 4 [[(2Z) 3,6 DIMETHYL 4 PROPOXY 2 (P TOLYLIMINO)BENBENZIMIDAZOL1YL]METHYL] N (1H TETRAZOL 5 YL)BENZAMIDE; 4 CHLORO 2 [[ 2 (2,5 DIMETHYL 4 NITRO PYRAZOL 3 YL)VINYL]AMINO]PHENOL]; 6 (2,5 DICHLOROBENZYL) 1 HYDROXY 2 (2 MORPHOLIN 4 YLETHYL) 1,6 DIHYDROPYRROLO[3',4' : 5,6]PYRIDO[3,4 B]INDOL 3(2H) ONE); [3 CYANO 5 [3 [(2,4 DICHLOROPHENYL) METHYL] 1,2,4 OXADIAOXADIAZOL 5 YL] 4 METHYL 2 THIENYL] 2 ETHYL BUTAN AMIDE; [5 [6,7 DICHLORO 3 [1 [1 (1 METHYL 4 PIPERIDYL)ETHYL]TETRAZOL 5 YL]SULFANYL QUINOXALIN 2 YL]THIAZOL 2 OL]; AMIDE; ANTHRACENE DERIVATIVE; ANTIDIABETIC AGENT; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HORMONE RECEPTOR BLOCKING AGENT; IMIDAZOPYRIDINE DERIVATIVE; N TERT BUTYL 6,7 DICHLORO 3 METHYLSULFONYL QUINOXALIN 2 AMINE; PHENYLALANINE DERIVATIVE; PNU 126814; PYRAZOLE DERIVATIVE; QUERCETIN DERIVATIVE; T 0632; TTP 054; UNCLASSIFIED DRUG; UNINDEXED DRUG; GLUCAGON LIKE PEPTIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE RECEPTOR; LIGAND;

DRUG RECEPTOR BINDING; HUMAN; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; DRUG DEVELOPMENT; DRUG POTENTIATION; METABOLISM;

DIABETES MELLITUS, TYPE 2; DRUG DISCOVERY; HUMANS; LIGANDS; RECEPTORS, GLUCAGON;

EID: 84862294240     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/709893     Document Type: Review

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