SCOPUS 정보 검색 플랫폼

ChemMedChem

Volumn 6, Issue 12, 2011, Pages 2159-2169

Structure-Based Discovery of Allosteric Modulators of Two Related ClassB G-Protein-Coupled Receptors

(5) deGraaf, Chris a,b Rein, Chantal c Piwnica, David c Giordanetto, Fabrizio d Rognan, Didier a

a Institut du Médicament de Strasbourg (France)

b VU UNIVERSITY AMSTERDAM (Netherlands)

c CEREP (France)

d ASTRAZENECA R AND D (Sweden)

Author keywords

Allosteric modulators; Gproteins; Receptors; Secretin; Virtual screening

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GLUCAGON; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON RECEPTOR; L 168049; RECEPTOR BLOCKING AGENT; SECRETIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; VIRTUAL REALITY; WHOLE CELL;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; DATABASES, FACTUAL; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, GLUCAGON; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 82255172411 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100317 Document Type: Article

Times cited : (65)

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