A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 3, 2007, Pages 943-948

  Chen, Desu ^a   Liao, Jiayu ^a,c   Li, Na ^a   Zhou, Caihong ^a   Liu, Qing ^a   Wang, Guangxing ^a   Zhang, Rui ^a   Zhang, Song ^a   Lin, Lilin ^a   Chen, Kaixian ^a,b   Xie, Xin ^a   Nan, Fajun ^a,b   Young, Andrew A ^a,d   Wang, Ming Wei ^a  

^a National Center for Drug Screening   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c University of California Riverside   (United States)

^d AMYLIN PHARMACEUTICALS INC   (United States)

Author keywords

Diabetes; Metabolism; Therapeutics

Indexed keywords

CYCLOBUTANE DERIVATIVE; DIPEPTIDYL PEPTIDASE IV; EXENDIN 4; EXENDIN[9-39]; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; HEMOGLOBIN A1C; INSULIN; NC 133908; NC 133909; SH 14800; SH 17249; SH 7870; SH 7871; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG HALF LIFE; FEMALE; FOOD INTAKE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOGLYCEMIA; INSULIN RELEASE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; REPORTER GENE;

ACUTE DISEASE; ANIMALS; CELL LINE; CHRONIC DISEASE; DIABETES MELLITUS; DRUG EVALUATION, PRECLINICAL; FEMALE; MALE; MICE; MOLECULAR STRUCTURE; PEPTIDES; RATS; RECEPTORS, GLUCAGON;

ANIMALIA; MUS; RATTUS;

EID: 33846536365     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610173104     Document Type: Article

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