-
1
-
-
79957900741
-
Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease
-
H. Yao, and I. Rahman Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease Toxicol Appl Pharmacol 254 2011 72 85
-
(2011)
Toxicol Appl Pharmacol
, vol.254
, pp. 72-85
-
-
Yao, H.1
Rahman, I.2
-
2
-
-
0022272160
-
Free-radical chemistry of cigarette smoke and its toxicological implications
-
D.F. Church, and W.A. Pryor Free-radical chemistry of cigarette smoke and its toxicological implications Environ Health Perspect 64 1985 111 126
-
(1985)
Environ Health Perspect
, vol.64
, pp. 111-126
-
-
Church, D.F.1
Pryor, W.A.2
-
3
-
-
15544388126
-
Oral N-acetylcysteine attenuates elastase-induced pulmonary emphysema in rats
-
M.L. Rubio, M.C. Martin-Mosquero, M. Ortega, G. Peces-Barba, and N. Gonzalez-Mangado Oral N-acetylcysteine attenuates elastase-induced pulmonary emphysema in rats Chest 125 2004 1500 1506
-
(2004)
Chest
, vol.125
, pp. 1500-1506
-
-
Rubio, M.L.1
Martin-Mosquero, M.C.2
Ortega, M.3
Peces-Barba, G.4
Gonzalez-Mangado, N.5
-
4
-
-
80051635385
-
Oxidation of Z alpha1-antitrypsin by cigarette smoke induces polymerization: A novel mechanism of early-onset emphysema
-
S. Alam, Z. Li, S. Janciauskiene, and R. Mahadeva Oxidation of Z alpha1-antitrypsin by cigarette smoke induces polymerization: a novel mechanism of early-onset emphysema Am J Respir Cell Mol Biol 45 2011 261 269
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 261-269
-
-
Alam, S.1
Li, Z.2
Janciauskiene, S.3
Mahadeva, R.4
-
5
-
-
0028361231
-
Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue
-
M.M. Bridgeman, M. Marsden, C. Selby, D. Morrison, and W. MacNee Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue Thorax 49 1994 670 675
-
(1994)
Thorax
, vol.49
, pp. 670-675
-
-
Bridgeman, M.M.1
Marsden, M.2
Selby, C.3
Morrison, D.4
MacNee, W.5
-
6
-
-
0034961209
-
The Bronchitis Randomized on NAC Cost-Utility Study (BRONCUS): Hypothesis and design. BRONCUS-trial Committee
-
M. Decramer, P.N. Dekhuijzen, T. Troosters, C. van Herwaarden, M. Rutten-van Molken, C.P. van Schayck, D. Olivieri, I. Lankhorst, and A. Ardia The Bronchitis Randomized on NAC Cost-Utility Study (BRONCUS): hypothesis and design. BRONCUS-trial Committee Eur Respir J 17 2001 329 336
-
(2001)
Eur Respir J
, vol.17
, pp. 329-336
-
-
Decramer, M.1
Dekhuijzen, P.N.2
Troosters, T.3
Van Herwaarden, C.4
Rutten-Van Molken, M.5
Van Schayck, C.P.6
Olivieri, D.7
Lankhorst, I.8
Ardia, A.9
-
7
-
-
20944433417
-
Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): A randomised placebo-controlled trial
-
M. Decramer, M. Rutten-van Molken, P.N. Dekhuijzen, T. Troosters, C. van Herwaarden, R. Pellegrino, C.P. van Schayck, D. Olivieri, M. Del Donno, and W. De Backer Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial Lancet 365 2005 1552 1560
-
(2005)
Lancet
, vol.365
, pp. 1552-1560
-
-
Decramer, M.1
Rutten-Van Molken, M.2
Dekhuijzen, P.N.3
Troosters, T.4
Van Herwaarden, C.5
Pellegrino, R.6
Van Schayck, C.P.7
Olivieri, D.8
Del Donno, M.9
De Backer, W.10
-
8
-
-
0035954121
-
Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: Systematic review
-
P.J. Poole, and P.N. Black Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review BMJ 322 2001 1271 1274
-
(2001)
BMJ
, vol.322
, pp. 1271-1274
-
-
Poole, P.J.1
Black, P.N.2
-
9
-
-
0242363130
-
Preventing exacerbations of chronic bronchitis and COPD: Therapeutic potential of mucolytic agents
-
P.J. Poole, and P.N. Black Preventing exacerbations of chronic bronchitis and COPD: therapeutic potential of mucolytic agents Am J Respir Med 2 2003 367 370
-
(2003)
Am J Respir Med
, vol.2
, pp. 367-370
-
-
Poole, P.J.1
Black, P.N.2
-
10
-
-
0033898870
-
The effect of oral N-acetylcysteine in chronic bronchitis: A quantitative systematic review
-
C. Stey, J. Steurer, S. Bachmann, T.C. Medici, and M.R. Tramer The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review Eur Respir J 16 2000 253 262
-
(2000)
Eur Respir J
, vol.16
, pp. 253-262
-
-
Stey, C.1
Steurer, J.2
Bachmann, S.3
Medici, T.C.4
Tramer, M.R.5
-
11
-
-
0034023927
-
Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: A meta-analysis of published double-blind, placebo-controlled clinical trials
-
E.M. Grandjean, P. Berthet, R. Ruffmann, and P. Leuenberger Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clinical trials Clin Ther 22 2000 209 221
-
(2000)
Clin Ther
, vol.22
, pp. 209-221
-
-
Grandjean, E.M.1
Berthet, P.2
Ruffmann, R.3
Leuenberger, P.4
-
12
-
-
0034942666
-
Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease
-
M. Kasielski, and D. Nowak Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease Respir Med 95 2001 448 456
-
(2001)
Respir Med
, vol.95
, pp. 448-456
-
-
Kasielski, M.1
Nowak, D.2
-
13
-
-
13144274594
-
Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease ISRCTN21676344
-
P.N. Black, A. Morgan-Day, T.E. McMillan, P.J. Poole, and R.P. Young Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease ISRCTN21676344 BMC Pulm Med 4 2004 13
-
(2004)
BMC Pulm Med
, vol.4
, pp. 13
-
-
Black, P.N.1
Morgan-Day, A.2
McMillan, T.E.3
Poole, P.J.4
Young, R.P.5
-
14
-
-
31344465272
-
New developments in the treatment of COPD: Comparing the effects of inhaled corticosteroids and N-acetylcysteine
-
F.J. van Overveld, U. Demkow, D. Gorecka, W.A. de Backer, and J. Zielinski New developments in the treatment of COPD: comparing the effects of inhaled corticosteroids and N-acetylcysteine J Physiol Pharmacol 56 2005 135 142
-
(2005)
J Physiol Pharmacol
, vol.56
, pp. 135-142
-
-
Van Overveld, F.J.1
Demkow, U.2
Gorecka, D.3
De Backer, W.A.4
Zielinski, J.5
-
15
-
-
10644250916
-
Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD
-
F. De Benedetto, A. Aceto, B. Dragani, A. Spacone, S. Formisano, R. Pela, C.F. Donner, and C.M. Sanguinetti Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD Pulm Pharmacol Ther 18 2005 41 47
-
(2005)
Pulm Pharmacol Ther
, vol.18
, pp. 41-47
-
-
De Benedetto, F.1
Aceto, A.2
Dragani, B.3
Spacone, A.4
Formisano, S.5
Pela, R.6
Donner, C.F.7
Sanguinetti, C.M.8
-
16
-
-
20844451178
-
The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: The EQUALIFE Study
-
M. Moretti, P. Bottrighi, R. Dallari, R. Da Porto, A. Dolcetti, P. Grandi, G. Garuti, E. Guffanti, P. Roversi, and M. De Gugliemo The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: the EQUALIFE Study Drugs Exp Clin Res 30 2004 143 152
-
(2004)
Drugs Exp Clin Res
, vol.30
, pp. 143-152
-
-
Moretti, M.1
Bottrighi, P.2
Dallari, R.3
Da Porto, R.4
Dolcetti, A.5
Grandi, P.6
Garuti, G.7
Guffanti, E.8
Roversi, P.9
De Gugliemo, M.10
-
17
-
-
44849100529
-
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): A randomised placebo-controlled study
-
J.P. Zheng, J. Kang, S.G. Huang, P. Chen, W.Z. Yao, L. Yang, C.X. Bai, C.Z. Wang, C. Wang, and B.Y. Chen Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study Lancet 371 2008 2013 2018
-
(2008)
Lancet
, vol.371
, pp. 2013-2018
-
-
Zheng, J.P.1
Kang, J.2
Huang, S.G.3
Chen, P.4
Yao, W.Z.5
Yang, L.6
Bai, C.X.7
Wang, C.Z.8
Wang, C.9
Chen, B.Y.10
-
18
-
-
0036195556
-
Effects of oral administration of N-acetyl-l-cysteine: A multi-biomarker study in smokers
-
F.J. Van Schooten, A. Besaratinia, S. De Flora, F. D'Agostini, A. Izzotti, A. Camoirano, A.J. Balm, J.W. Dallinga, A. Bast, and G.R. Haenen Effects of oral administration of N-acetyl-l-cysteine: a multi-biomarker study in smokers Cancer Epidemiol Biomarkers Prev 11 2002 167 175
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 167-175
-
-
Van Schooten, F.J.1
Besaratinia, A.2
De Flora, S.3
D'Agostini, F.4
Izzotti, A.5
Camoirano, A.6
Balm, A.J.7
Dallinga, J.W.8
Bast, A.9
Haenen, G.R.10
-
19
-
-
0037718518
-
N-acetylcysteine reduces the risk of re-hospitalisation among patients with chronic obstructive pulmonary disease
-
C.M. Gerrits, R.M. Herings, H.G. Leufkens, and J.W. Lammers N-acetylcysteine reduces the risk of re-hospitalisation among patients with chronic obstructive pulmonary disease Eur Respir J 21 2003 795 798
-
(2003)
Eur Respir J
, vol.21
, pp. 795-798
-
-
Gerrits, C.M.1
Herings, R.M.2
Leufkens, H.G.3
Lammers, J.W.4
-
20
-
-
1842428854
-
Does systemic inflammation trigger local exercise-induced oxidative stress in COPD?
-
C. Koechlin, A. Couillard, J.P. Cristol, P. Chanez, M. Hayot, D. Le Gallais, and C. Prefaut Does systemic inflammation trigger local exercise-induced oxidative stress in COPD? Eur Respir J 23 2004 538 544
-
(2004)
Eur Respir J
, vol.23
, pp. 538-544
-
-
Koechlin, C.1
Couillard, A.2
Cristol, J.P.3
Chanez, P.4
Hayot, M.5
Le Gallais, D.6
Prefaut, C.7
-
21
-
-
0025615316
-
Long-lasting effects on rheology and clearance of bronchial mucus after short-term administration of high doses of carbocysteine-lysine to patients with chronic bronchitis
-
P.C. Braga, L. Allegra, C. Rampoldi, A. Ornaghi, and G. Beghi Long-lasting effects on rheology and clearance of bronchial mucus after short-term administration of high doses of carbocysteine-lysine to patients with chronic bronchitis Respiration 57 1990 353 358
-
(1990)
Respiration
, vol.57
, pp. 353-358
-
-
Braga, P.C.1
Allegra, L.2
Rampoldi, C.3
Ornaghi, A.4
Beghi, G.5
-
22
-
-
79955758951
-
Carbocisteine protects against emphysema induced by cigarette smoke extract in rats
-
M. Hanaoka, Y. Droma, Y. Chen, T. Agatsuma, Y. Kitaguchi, N.F. Voelkel, and K. Kubo Carbocisteine protects against emphysema induced by cigarette smoke extract in rats Chest 139 2011 1101 1108
-
(2011)
Chest
, vol.139
, pp. 1101-1108
-
-
Hanaoka, M.1
Droma, Y.2
Chen, Y.3
Agatsuma, T.4
Kitaguchi, Y.5
Voelkel, N.F.6
Kubo, K.7
-
23
-
-
8844273362
-
Exhaled Interleukine-6 and 8-isoprostane in chronic obstructive pulmonary disease: Effect of carbocysteine lysine salt monohydrate (SCMC-Lys)
-
G.E. Carpagnano, O. Resta, M.P. Foschino-Barbaro, A. Spanevello, A. Stefano, G. Di Gioia, G. Serviddio, and E. Gramiccioni Exhaled Interleukine-6 and 8-isoprostane in chronic obstructive pulmonary disease: effect of carbocysteine lysine salt monohydrate (SCMC-Lys) Eur J Pharmacol 505 2004 169 175
-
(2004)
Eur J Pharmacol
, vol.505
, pp. 169-175
-
-
Carpagnano, G.E.1
Resta, O.2
Foschino-Barbaro, M.P.3
Spanevello, A.4
Stefano, A.5
Di Gioia, G.6
Serviddio, G.7
Gramiccioni, E.8
-
24
-
-
0345004819
-
The effects of S-carboxymethylcysteine and N-acetylcysteine on the adherence of Moraxella catarrhalis to human pharyngeal epithelial cells
-
C.H. Zheng, K. Ahmed, N. Rikitomi, G. Martinez, and T. Nagatake The effects of S-carboxymethylcysteine and N-acetylcysteine on the adherence of Moraxella catarrhalis to human pharyngeal epithelial cells Microbiol Immunol 43 1999 107 113
-
(1999)
Microbiol Immunol
, vol.43
, pp. 107-113
-
-
Zheng, C.H.1
Ahmed, K.2
Rikitomi, N.3
Martinez, G.4
Nagatake, T.5
-
25
-
-
0038023151
-
S-carboxymethylcysteine inhibits the attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells
-
G. Cakan, M. Turkoz, T. Turan, K. Ahmed, and T. Nagatake S-carboxymethylcysteine inhibits the attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells Microb Pathog 34 2003 261 265
-
(2003)
Microb Pathog
, vol.34
, pp. 261-265
-
-
Cakan, G.1
Turkoz, M.2
Turan, T.3
Ahmed, K.4
Nagatake, T.5
-
26
-
-
35748947732
-
Carbocisteine improves quality of life in patients with chronic obstructive pulmonary disease
-
K. Tatsumi, and Y. Fukuchi Carbocisteine improves quality of life in patients with chronic obstructive pulmonary disease J Am Geriatr Soc 55 2007 1884 1886
-
(2007)
J Am Geriatr Soc
, vol.55
, pp. 1884-1886
-
-
Tatsumi, K.1
Fukuchi, Y.2
-
27
-
-
0016263725
-
An assessment of S-carboxymethylcysteine in the treatment of chronic bronchitis
-
M. Aylward An assessment of S-carboxymethylcysteine in the treatment of chronic bronchitis Curr Med Res Opin 2 1974 387 394
-
(1974)
Curr Med Res Opin
, vol.2
, pp. 387-394
-
-
Aylward, M.1
-
28
-
-
0017171687
-
S-carboxymethylcysteine in the fluidification of sputum and treatment of chronic airway obstruction
-
G.F. Edwards, A.E. Steel, J.K. Scott, and J.W. Jordan S-carboxymethylcysteine in the fluidification of sputum and treatment of chronic airway obstruction Chest 70 1976 506 513
-
(1976)
Chest
, vol.70
, pp. 506-513
-
-
Edwards, G.F.1
Steel, A.E.2
Scott, J.K.3
Jordan, J.W.4
-
29
-
-
0020451480
-
Double blind study of carbocysteine against placebo in chronic bronchitis: Mucoregulation in respiratory tract disorders
-
G. Miskoviti, P. Szule, and K. Mescaros Double blind study of carbocysteine against placebo in chronic bronchitis: mucoregulation in respiratory tract disorders Proc R Soc Med 5 1982 1 3
-
(1982)
Proc R Soc Med
, vol.5
, pp. 1-3
-
-
Miskoviti, G.1
Szule, P.2
Mescaros, K.3
-
30
-
-
0017046086
-
Rheology of bronchial secretions and mucociliary transport (author's transl)
-
E. Puchelle, F. Girard, and J.M. Zahm Rheology of bronchial secretions and mucociliary transport (author's transl) Bull Eur Physiopathol Respir 12 1976 771 779
-
(1976)
Bull Eur Physiopathol Respir
, vol.12
, pp. 771-779
-
-
Puchelle, E.1
Girard, F.2
Zahm, J.M.3
-
31
-
-
0029947365
-
Prevention of acute exacerbations of chronic obstructive bronchitis with carbocysteine lysine salt monohydrate: A multicenter, double-blind, placebo-controlled trial
-
L. Allegra, C.I. Cordaro, and C. Grassi Prevention of acute exacerbations of chronic obstructive bronchitis with carbocysteine lysine salt monohydrate: a multicenter, double-blind, placebo-controlled trial Respiration 63 1996 174 180
-
(1996)
Respiration
, vol.63
, pp. 174-180
-
-
Allegra, L.1
Cordaro, C.I.2
Grassi, C.3
-
32
-
-
0022298166
-
Long-term oral carbocisteine therapy in patients with chronic bronchitis. A double blind trial with placebo control
-
M. Grillage, and K. Barnard-Jones Long-term oral carbocisteine therapy in patients with chronic bronchitis. A double blind trial with placebo control Br J Clin Pract 39 1985 395 398
-
(1985)
Br J Clin Pract
, vol.39
, pp. 395-398
-
-
Grillage, M.1
Barnard-Jones, K.2
-
33
-
-
33645091653
-
Carbocisteine reduces frequency of common colds and exacerbations in patients with chronic obstructive pulmonary disease
-
H. Yasuda, M. Yamaya, T. Sasaki, D. Inoue, K. Nakayama, N. Tomita, M. Yoshida, and H. Sasaki Carbocisteine reduces frequency of common colds and exacerbations in patients with chronic obstructive pulmonary disease J Am Geriatr Soc 54 2006 378 380
-
(2006)
J Am Geriatr Soc
, vol.54
, pp. 378-380
-
-
Yasuda, H.1
Yamaya, M.2
Sasaki, T.3
Inoue, D.4
Nakayama, K.5
Tomita, N.6
Yoshida, M.7
Sasaki, H.8
-
34
-
-
33750482082
-
Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells
-
H. Yasuda, M. Yamaya, T. Sasaki, D. Inoue, K. Nakayama, M. Yamada, M. Asada, M. Yoshida, T. Suzuki, and H. Nishimura Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells Eur Respir J 28 2006 51 58
-
(2006)
Eur Respir J
, vol.28
, pp. 51-58
-
-
Yasuda, H.1
Yamaya, M.2
Sasaki, T.3
Inoue, D.4
Nakayama, K.5
Yamada, M.6
Asada, M.7
Yoshida, M.8
Suzuki, T.9
Nishimura, H.10
-
35
-
-
85016625765
-
Pharmacology and clinical efficacy of erdosteine in chronic obstructive pulmonary disease
-
M. Moretti Pharmacology and clinical efficacy of erdosteine in chronic obstructive pulmonary disease Expert Rev Respir Med 1 2007 307 316
-
(2007)
Expert Rev Respir Med
, vol.1
, pp. 307-316
-
-
Moretti, M.1
-
36
-
-
75749085711
-
The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: A meta-analysis of individual patient data
-
M. Cazzola, I. Floriani, and C.P. Page The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: a meta-analysis of individual patient data Pulm Pharmacol Ther 23 2010 135 144
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 135-144
-
-
Cazzola, M.1
Floriani, I.2
Page, C.P.3
-
37
-
-
40149108576
-
Erdosteine: Antitussive and anti-inflammatory effects
-
R.W. Dal Negro Erdosteine: antitussive and anti-inflammatory effects Lung 186 Suppl. 1 2008 S70 S73
-
(2008)
Lung
, vol.186
, Issue.SUPPL. 1
-
-
Dal Negro, R.W.1
-
38
-
-
66149192420
-
Alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases
-
N. Moretto, F. Facchinetti, T. Southworth, M. Civelli, D. Singh, and R. Patacchini alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases Am J Physiol Lung Cell Mol Physiol 296 2009 L839 L848
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.296
-
-
Moretto, N.1
Facchinetti, F.2
Southworth, T.3
Civelli, M.4
Singh, D.5
Patacchini, R.6
-
40
-
-
58849084547
-
Effect of fudosteine on mucin production
-
C.K. Rhee, C.M. Kang, M.B. You, H.K. Yoon, Y.K. Kim, K.H. Kim, H.S. Moon, S.H. Park, and J.S. Song Effect of fudosteine on mucin production Eur Respir J 32 2008 1195 1202
-
(2008)
Eur Respir J
, vol.32
, pp. 1195-1202
-
-
Rhee, C.K.1
Kang, C.M.2
You, M.B.3
Yoon, H.K.4
Kim, Y.K.5
Kim, K.H.6
Moon, H.S.7
Park, S.H.8
Song, J.S.9
-
41
-
-
66649127216
-
Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine
-
G.O. Osoata, T. Hanazawa, C. Brindicci, M. Ito, P.J. Barnes, S. Kharitonov, and K. Ito Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine Chest 135 2009 1513 1520
-
(2009)
Chest
, vol.135
, pp. 1513-1520
-
-
Osoata, G.O.1
Hanazawa, T.2
Brindicci, C.3
Ito, M.4
Barnes, P.J.5
Kharitonov, S.6
Ito, K.7
-
42
-
-
11844288305
-
Inhibition of endotoxin- and antigen-induced airway inflammation by fudosteine, a mucoactive agent
-
H. Komatsu, S. Yamaguchi, N. Komorita, K. Goto, S. Takagi, H. Ochi, and T. Okumoto Inhibition of endotoxin- and antigen-induced airway inflammation by fudosteine, a mucoactive agent Pulm Pharmacol Ther 18 2005 121 127
-
(2005)
Pulm Pharmacol Ther
, vol.18
, pp. 121-127
-
-
Komatsu, H.1
Yamaguchi, S.2
Komorita, N.3
Goto, K.4
Takagi, S.5
Ochi, H.6
Okumoto, T.7
-
43
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
T.W. Kensler, N. Wakabayashi, and S. Biswal Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway Annu Rev Pharmacol Toxicol 47 2007 89 116
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
44
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
T. Rangasamy, J. Guo, W.A. Mitzner, J. Roman, A. Singh, A.D. Fryer, M. Yamamoto, T.W. Kensler, R.M. Tuder, and S.N. Georas Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice J Exp Med 202 2005 47 59
-
(2005)
J Exp Med
, vol.202
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
Yamamoto, M.7
Kensler, T.W.8
Tuder, R.M.9
Georas, S.N.10
-
45
-
-
58549105575
-
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
-
T.E. Sussan, T. Rangasamy, D.J. Blake, D. Malhotra, H. El-Haddad, D. Bedja, M.S. Yates, P. Kombairaju, M. Yamamoto, and K.T. Liby Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice Proc Natl Acad Sci U S A 106 2009 250 255
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 250-255
-
-
Sussan, T.E.1
Rangasamy, T.2
Blake, D.J.3
Malhotra, D.4
El-Haddad, H.5
Bedja, D.6
Yates, M.S.7
Kombairaju, P.8
Yamamoto, M.9
Liby, K.T.10
-
46
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
T. Rangasamy, C.Y. Cho, R.K. Thimmulappa, L. Zhen, S.S. Srisuma, T.W. Kensler, M. Yamamoto, I. Petrache, R.M. Tuder, and S. Biswal Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice J Clin Invest 114 2004 1248 1259
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
47
-
-
29244473882
-
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema
-
T. Iizuka, Y. Ishii, K. Itoh, T. Kiwamoto, T. Kimura, Y. Matsuno, Y. Morishima, A.E. Hegab, S. Homma, and A. Nomura Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema Genes Cells 10 2005 1113 1125
-
(2005)
Genes Cells
, vol.10
, pp. 1113-1125
-
-
Iizuka, T.1
Ishii, Y.2
Itoh, K.3
Kiwamoto, T.4
Kimura, T.5
Matsuno, Y.6
Morishima, Y.7
Hegab, A.E.8
Homma, S.9
Nomura, A.10
-
48
-
-
53649099660
-
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema
-
D. Goven, A. Boutten, V. Lecon-Malas, J. Marchal-Somme, N. Amara, B. Crestani, M. Fournier, G. Leseche, P. Soler, and J. Boczkowski Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema Thorax 63 2008 916 924
-
(2008)
Thorax
, vol.63
, pp. 916-924
-
-
Goven, D.1
Boutten, A.2
Lecon-Malas, V.3
Marchal-Somme, J.4
Amara, N.5
Crestani, B.6
Fournier, M.7
Leseche, G.8
Soler, P.9
Boczkowski, J.10
-
49
-
-
51849129227
-
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
-
D. Malhotra, R. Thimmulappa, A. Navas-Acien, A. Sandford, M. Elliott, A. Singh, L. Chen, X. Zhuang, J. Hogg, and P. Pare Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1 Am J Respir Crit Care Med 178 2008 592 604
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 592-604
-
-
Malhotra, D.1
Thimmulappa, R.2
Navas-Acien, A.3
Sandford, A.4
Elliott, M.5
Singh, A.6
Chen, L.7
Zhuang, X.8
Hogg, J.9
Pare, P.10
-
50
-
-
57349151482
-
Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease
-
M. Suzuki, T. Betsuyaku, Y. Ito, K. Nagai, Y. Nasuhara, K. Kaga, S. Kondo, and M. Nishimura Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease Am J Respir Cell Mol Biol 39 2008 673 682
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 673-682
-
-
Suzuki, M.1
Betsuyaku, T.2
Ito, Y.3
Nagai, K.4
Nasuhara, Y.5
Kaga, K.6
Kondo, S.7
Nishimura, M.8
-
51
-
-
41549108838
-
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
-
A. Kode, S. Rajendrasozhan, S. Caito, S.R. Yang, I.L. Megson, and I. Rahman Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells Am J Physiol Lung Cell Mol Physiol 294 2008 L478 L488
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Kode, A.1
Rajendrasozhan, S.2
Caito, S.3
Yang, S.R.4
Megson, I.L.5
Rahman, I.6
-
52
-
-
80555124930
-
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
-
D. Malhotra, R.K. Thimmulappa, N. Mercado, K. Ito, P. Kombairaju, S. Kumar, J. Ma, D. Feller-Kopman, R. Wise, and P. Barnes Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients J Clin Invest 121 2011 4289 4302
-
(2011)
J Clin Invest
, vol.121
, pp. 4289-4302
-
-
Malhotra, D.1
Thimmulappa, R.K.2
Mercado, N.3
Ito, K.4
Kombairaju, P.5
Kumar, S.6
Ma, J.7
Feller-Kopman, D.8
Wise, R.9
Barnes, P.10
-
53
-
-
29244443231
-
Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera
-
J.H. Lee, H.S. Jung, P.M. Giang, X. Jin, S. Lee, P.T. Son, D. Lee, Y.S. Hong, K. Lee, and J.J. Lee Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera J Pharmacol Exp Ther 316 2006 271 278
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 271-278
-
-
Lee, J.H.1
Jung, H.S.2
Giang, P.M.3
Jin, X.4
Lee, S.5
Son, P.T.6
Lee, D.7
Hong, Y.S.8
Lee, K.9
Lee, J.J.10
-
54
-
-
33847633373
-
Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile
-
Y.C. Liu, C.W. Hsieh, C.C. Wu, and B.S. Wung Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile Life Sci 80 2007 1420 1430
-
(2007)
Life Sci
, vol.80
, pp. 1420-1430
-
-
Liu, Y.C.1
Hsieh, C.W.2
Wu, C.C.3
Wung, B.S.4
-
55
-
-
13244284674
-
Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells
-
R. Foresti, M. Hoque, D. Monti, C.J. Green, and R. Motterlini Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells J Pharmacol Exp Ther 312 2005 686 693
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 686-693
-
-
Foresti, R.1
Hoque, M.2
Monti, D.3
Green, C.J.4
Motterlini, R.5
-
56
-
-
79959429766
-
Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells
-
V. Kumar, S. Kumar, M. Hassan, H. Wu, R.K. Thimmulappa, A. Kumar, S.K. Sharma, V.S. Parmar, S. Biswal, and S.V. Malhotra Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells J Med Chem 54 2011 4147 4159
-
(2011)
J Med Chem
, vol.54
, pp. 4147-4159
-
-
Kumar, V.1
Kumar, S.2
Hassan, M.3
Wu, H.4
Thimmulappa, R.K.5
Kumar, A.6
Sharma, S.K.7
Parmar, V.S.8
Biswal, S.9
Malhotra, S.V.10
-
57
-
-
58849096654
-
Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice
-
S. Tajima, M. Bando, Y. Ishii, T. Hosono, H. Yamasawa, S. Ohno, T. Takada, E. Suzuki, F. Gejyo, and Y. Sugiyama Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice Eur Respir J 32 2008 1337 1343
-
(2008)
Eur Respir J
, vol.32
, pp. 1337-1343
-
-
Tajima, S.1
Bando, M.2
Ishii, Y.3
Hosono, T.4
Yamasawa, H.5
Ohno, S.6
Takada, T.7
Suzuki, E.8
Gejyo, F.9
Sugiyama, Y.10
-
58
-
-
80053510027
-
Beyond neurological disease: New targets for edaravone (review)
-
K. Kikuchi, H. Uchikado, N. Miyagi, Y. Morimoto, T. Ito, S. Tancharoen, N. Miura, K. Miyata, R. Sakamoto, and C. Kikuchi Beyond neurological disease: new targets for edaravone (review) Int J Mol Med 28 2011 899 906
-
(2011)
Int J Mol Med
, vol.28
, pp. 899-906
-
-
Kikuchi, K.1
Uchikado, H.2
Miyagi, N.3
Morimoto, Y.4
Ito, T.5
Tancharoen, S.6
Miura, N.7
Miyata, K.8
Sakamoto, R.9
Kikuchi, C.10
-
59
-
-
75149193424
-
Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: Focus on reactivity, selectivity, and reaction mechanisms
-
G. Aldini, G. Vistoli, L. Regazzoni, M.C. Benfatto, I. Bettinelli, and M. Carini Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms Antioxid Redox Signal 12 2010 381 392
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 381-392
-
-
Aldini, G.1
Vistoli, G.2
Regazzoni, L.3
Benfatto, M.C.4
Bettinelli, I.5
Carini, M.6
-
60
-
-
35649008900
-
Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls
-
G. Aldini, I. Dalle-Donne, R.M. Facino, A. Milzani, and M. Carini Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls Med Res Rev 27 2007 817 868
-
(2007)
Med Res Rev
, vol.27
, pp. 817-868
-
-
Aldini, G.1
Dalle-Donne, I.2
Facino, R.M.3
Milzani, A.4
Carini, M.5
-
61
-
-
11344260687
-
Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat
-
K. Ito, H. Ozasa, and S. Horikawa Edaravone protects against lung injury induced by intestinal ischemia/reperfusion in rat Free Radic Biol Med 38 2005 369 374
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 369-374
-
-
Ito, K.1
Ozasa, H.2
Horikawa, S.3
-
62
-
-
0023184568
-
Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation
-
J.M. Braughler, J.F. Pregenzer, R.L. Chase, L.A. Duncan, E.J. Jacobsen, and J.M. McCall Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation J Biol Chem 262 1987 10438 10440
-
(1987)
J Biol Chem
, vol.262
, pp. 10438-10440
-
-
Braughler, J.M.1
Pregenzer, J.F.2
Chase, R.L.3
Duncan, L.A.4
Jacobsen, E.J.5
McCall, J.M.6
-
63
-
-
0030014151
-
U-74389 F attenuates phorbol ester-induced lung injury in rabbits
-
M. Miniati, F. Cocci, S. Monti, E. Filippi, R. Sarnelli, M. Ferdeghini, V. Gattai, M. Pistolesi, and Lazaroid U-74389 F attenuates phorbol ester-induced lung injury in rabbits Eur Respir J 9 1996 758 764
-
(1996)
Eur Respir J
, vol.9
, pp. 758-764
-
-
Miniati, M.1
Cocci, F.2
Monti, S.3
Filippi, E.4
Sarnelli, R.5
Ferdeghini, M.6
Gattai, V.7
Pistolesi, M.8
Lazaroid9
-
64
-
-
0028890741
-
Effects of treatment with the 21-aminosteroid, U7438 F, on pulmonary cytokine expression following hemorrhage and resuscitation
-
R. Shenkar, and E. Abraham Effects of treatment with the 21-aminosteroid, U7438 F, on pulmonary cytokine expression following hemorrhage and resuscitation Crit Care Med 23 1995 132 139
-
(1995)
Crit Care Med
, vol.23
, pp. 132-139
-
-
Shenkar, R.1
Abraham, E.2
-
65
-
-
0030811224
-
A free radical scavenger (Lazaroid U75412 E) attenuates tumor necrosis factor-alpha generation in a rabbit model of smoke-induced lung injury
-
S. Wang, R.C. Lantz, E.D. Rider, G.J. Chen, V. Breceda, A.M. Hays, R.F. Robledo, B.J. Tollinger, S.V. Dinesh, and M.L. Witten A free radical scavenger (Lazaroid U75412 E) attenuates tumor necrosis factor-alpha generation in a rabbit model of smoke-induced lung injury Respiration 64 1997 358 363
-
(1997)
Respiration
, vol.64
, pp. 358-363
-
-
Wang, S.1
Lantz, R.C.2
Rider, E.D.3
Chen, G.J.4
Breceda, V.5
Hays, A.M.6
Robledo, R.F.7
Tollinger, B.J.8
Dinesh, S.V.9
Witten, M.L.10
-
66
-
-
0033403210
-
Functional alterations of alveolar macrophages subjected to smoke exposure and antioxidant lazaroids
-
S. Wang, R.C. Lantz, M.W. Vermeulen, G.J. Chen, V. Breceda, R.F. Robledo, A.M. Hays, S. Young, and M.L. Witten Functional alterations of alveolar macrophages subjected to smoke exposure and antioxidant lazaroids Toxicol Ind Health 15 1999 464 469
-
(1999)
Toxicol Ind Health
, vol.15
, pp. 464-469
-
-
Wang, S.1
Lantz, R.C.2
Vermeulen, M.W.3
Chen, G.J.4
Breceda, V.5
Robledo, R.F.6
Hays, A.M.7
Young, S.8
Witten, M.L.9
-
67
-
-
0027322774
-
Attenuation of acute lung injury and oxygen radical production by the 21-aminosteroid, U-78518F
-
T. Tanigaki, Y. Suzuki, D. Heimer, H.H. Sussman, W.G. Ross, and T.A. Raffin Attenuation of acute lung injury and oxygen radical production by the 21-aminosteroid, U-78518F J Appl Physiol 74 1993 2155 2160
-
(1993)
J Appl Physiol
, vol.74
, pp. 2155-2160
-
-
Tanigaki, T.1
Suzuki, Y.2
Heimer, D.3
Sussman, H.H.4
Ross, W.G.5
Raffin, T.A.6
-
68
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
R.M. Tuder, L. Zhen, C.Y. Cho, L. Taraseviciene-Stewart, Y. Kasahara, D. Salvemini, N.F. Voelkel, and S.C. Flores Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade Am J Respir Cell Mol Biol 29 2003 88 97
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
, pp. 88-97
-
-
Tuder, R.M.1
Zhen, L.2
Cho, C.Y.3
Taraseviciene-Stewart, L.4
Kasahara, Y.5
Salvemini, D.6
Voelkel, N.F.7
Flores, S.C.8
-
69
-
-
4644313337
-
The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: Role of the lectin-like oxidized low-density lipoprotein receptor-1
-
C. Muscoli, I. Sacco, W. Alecce, E. Palma, R. Nistico, N. Costa, F. Clementi, D. Rotiroti, F. Romeo, and D. Salvemini The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1 J Pharmacol Exp Ther 311 2004 44 50
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 44-50
-
-
Muscoli, C.1
Sacco, I.2
Alecce, W.3
Palma, E.4
Nistico, R.5
Costa, N.6
Clementi, F.7
Rotiroti, D.8
Romeo, F.9
Salvemini, D.10
-
70
-
-
0036667559
-
Inhibition of airway inflammation and hyperreactivity by an antioxidant mimetic
-
L.Y. Chang, and J.D. Crapo Inhibition of airway inflammation and hyperreactivity by an antioxidant mimetic Free Radic Biol Med 33 2002 379 386
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 379-386
-
-
Chang, L.Y.1
Crapo, J.D.2
-
71
-
-
0037108012
-
Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant
-
K.R. Smith, D.L. Uyeminami, U.P. Kodavanti, J.D. Crapo, L.Y. Chang, and K.E. Pinkerton Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant Free Radic Biol Med 33 2002 1106 1114
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1106-1114
-
-
Smith, K.R.1
Uyeminami, D.L.2
Kodavanti, U.P.3
Crapo, J.D.4
Chang, L.Y.5
Pinkerton, K.E.6
-
72
-
-
0037103792
-
Oxidation of nitric oxide by oxomanganese-salen complexes: A new mechanism for cellular protection by superoxide dismutase/catalase mimetics
-
M.A. Sharpe, R. Ollosson, V.C. Stewart, and J.B. Clark Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics Biochem J 366 2002 97 107
-
(2002)
Biochem J
, vol.366
, pp. 97-107
-
-
Sharpe, M.A.1
Ollosson, R.2
Stewart, V.C.3
Clark, J.B.4
-
73
-
-
0033071046
-
Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappaB activation and IL-8 mRNA expression in guinea pigs in vivo
-
M. Nishikawa, N. Kakemizu, T. Ito, M. Kudo, T. Kaneko, M. Suzuki, N. Udaka, H. Ikeda, and T. Okubo Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappaB activation and IL-8 mRNA expression in guinea pigs in vivo Am J Respir Cell Mol Biol 20 1999 189 198
-
(1999)
Am J Respir Cell Mol Biol
, vol.20
, pp. 189-198
-
-
Nishikawa, M.1
Kakemizu, N.2
Ito, T.3
Kudo, M.4
Kaneko, T.5
Suzuki, M.6
Udaka, N.7
Ikeda, H.8
Okubo, T.9
-
74
-
-
0029555770
-
A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro
-
B.J. Day, S. Shawen, S.I. Liochev, and J.D. Crapo A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro J Pharmacol Exp Ther 275 1995 1227 1232
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1227-1232
-
-
Day, B.J.1
Shawen, S.2
Liochev, S.I.3
Crapo, J.D.4
-
75
-
-
0031573475
-
Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury
-
B.J. Day, I. Fridovich, and J.D. Crapo Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury Arch Biochem Biophys 347 1997 256 262
-
(1997)
Arch Biochem Biophys
, vol.347
, pp. 256-262
-
-
Day, B.J.1
Fridovich, I.2
Crapo, J.D.3
-
76
-
-
0042848453
-
Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion
-
G. Ferrer-Sueta, D. Vitturi, I. Batinic-Haberle, I. Fridovich, S. Goldstein, G. Czapski, and R. Radi Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion J Biol Chem 278 2003 27432 27438
-
(2003)
J Biol Chem
, vol.278
, pp. 27432-27438
-
-
Ferrer-Sueta, G.1
Vitturi, D.2
Batinic-Haberle, I.3
Fridovich, I.4
Goldstein, S.5
Czapski, G.6
Radi, R.7
-
77
-
-
1642505511
-
Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: Implication for their use in targeting oxidation-reduction reactions in innate immunity
-
H.M. Tse, M.J. Milton, and J.D. Piganelli Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation-reduction reactions in innate immunity Free Radic Biol Med 36 2004 233 247
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 233-247
-
-
Tse, H.M.1
Milton, M.J.2
Piganelli, J.D.3
-
78
-
-
2942713709
-
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury
-
Z. Vujaskovic, I. Batinic-Haberle, Z.N. Rabbani, Q.F. Feng, S.K. Kang, I. Spasojevic, T.V. Samulski, I. Fridovich, M.W. Dewhirst, and M.S. Anscher A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury Free Radic Biol Med 33 2002 857 863
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 857-863
-
-
Vujaskovic, Z.1
Batinic-Haberle, I.2
Rabbani, Z.N.3
Feng, Q.F.4
Kang, S.K.5
Spasojevic, I.6
Samulski, T.V.7
Fridovich, I.8
Dewhirst, M.W.9
Anscher, M.S.10
-
79
-
-
0038545583
-
Superoxide dismutases in the lung and human lung diseases
-
V.L. Kinnula, and J.D. Crapo Superoxide dismutases in the lung and human lung diseases Am J Respir Crit Care Med 167 2003 1600 1619
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1600-1619
-
-
Kinnula, V.L.1
Crapo, J.D.2
-
80
-
-
77957273815
-
Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM
-
H. Yao, G. Arunachalam, J.W. Hwang, S. Chung, I.K. Sundar, V.L. Kinnula, J.D. Crapo, and I. Rahman Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM Proc Natl Acad Sci U S A 107 2010 15571 15576
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15571-15576
-
-
Yao, H.1
Arunachalam, G.2
Hwang, J.W.3
Chung, S.4
Sundar, I.K.5
Kinnula, V.L.6
Crapo, J.D.7
Rahman, I.8
-
81
-
-
78650178291
-
Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress
-
A.K. Tollefson, R.E. Oberley-Deegan, K.T. Butterfield, M.E. Nicks, M.R. Weaver, L.K. Remigio, J. Decsesznak, H.W. Chu, D.L. Bratton, and D.W. Riches Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress Free Radic Biol Med 49 2010 1937 1946
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1937-1946
-
-
Tollefson, A.K.1
Oberley-Deegan, R.E.2
Butterfield, K.T.3
Nicks, M.E.4
Weaver, M.R.5
Remigio, L.K.6
Decsesznak, J.7
Chu, H.W.8
Bratton, D.L.9
Riches, D.W.10
-
82
-
-
0142231354
-
Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes
-
L. Jozsef, and J.G. Filep Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes Free Radic Biol Med 35 2003 1018 1027
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 1018-1027
-
-
Jozsef, L.1
Filep, J.G.2
-
83
-
-
0037100440
-
Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation
-
B. Haddad el, K. McCluskie, M.A. Birrell, D. Dabrowski, M. Pecoraro, S. Underwood, B. Chen, G.T. De Sanctis, S.E. Webber, and M.L. Foster Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation J Immunol 169 2002 974 982
-
(2002)
J Immunol
, vol.169
, pp. 974-982
-
-
Haddad El, B.1
McCluskie, K.2
Birrell, M.A.3
Dabrowski, D.4
Pecoraro, M.5
Underwood, S.6
Chen, B.7
De Sanctis, G.T.8
Webber, S.E.9
Foster, M.L.10
-
84
-
-
0036489191
-
Ebselen suppresses late airway responses and airway inflammation in guinea pigs
-
M. Zhang, A. Nomura, Y. Uchida, H. Iijima, T. Sakamoto, Y. Iishii, Y. Morishima, M. Mochizuki, K. Masuyama, and K. Hirano Ebselen suppresses late airway responses and airway inflammation in guinea pigs Free Radic Biol Med 32 2002 454 464
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 454-464
-
-
Zhang, M.1
Nomura, A.2
Uchida, Y.3
Iijima, H.4
Sakamoto, T.5
Iishii, Y.6
Morishima, Y.7
Mochizuki, M.8
Masuyama, K.9
Hirano, K.10
-
85
-
-
13044295425
-
BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: A promising neuroprotective strategy
-
P.E. Chabrier, M. Auguet, B. Spinnewyn, S. Auvin, S. Cornet, C. Demerle-Pallardy, C. Guilmard-Favre, J.G. Marin, B. Pignol, and V. Gillard-Roubert BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: a promising neuroprotective strategy Proc Natl Acad Sci U S A 96 1999 10824 10829
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 10824-10829
-
-
Chabrier, P.E.1
Auguet, M.2
Spinnewyn, B.3
Auvin, S.4
Cornet, S.5
Demerle-Pallardy, C.6
Guilmard-Favre, C.7
Marin, J.G.8
Pignol, B.9
Gillard-Roubert, V.10
-
86
-
-
16244368485
-
Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species
-
H. Shi, G. Timmins, M. Monske, A. Burdick, B. Kalyanaraman, Y. Liu, J.L. Clement, S. Burchiel, and K.J. Liu Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species Arch Biochem Biophys 437 2005 59 68
-
(2005)
Arch Biochem Biophys
, vol.437
, pp. 59-68
-
-
Shi, H.1
Timmins, G.2
Monske, M.3
Burdick, A.4
Kalyanaraman, B.5
Liu, Y.6
Clement, J.L.7
Burchiel, S.8
Liu, K.J.9
-
87
-
-
0141618446
-
Synthesis and EPR spin trapping properties of a new isoindole-based nitrone: 1,1,3-trimethylisoindole N-oxide (TMINO)
-
S.E. Bottle, and A.S. Micallef Synthesis and EPR spin trapping properties of a new isoindole-based nitrone: 1,1,3-trimethylisoindole N-oxide (TMINO) Org Biomol Chem 1 2003 2581 2584
-
(2003)
Org Biomol Chem
, vol.1
, pp. 2581-2584
-
-
Bottle, S.E.1
Micallef, A.S.2
-
88
-
-
0036570206
-
Stilbazulenyl nitrone (STAZN): A nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants
-
D.A. Becker, J.J. Ley, L. Echegoyen, and R. Alvarado Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants J Am Chem Soc 124 2002 4678 4684
-
(2002)
J Am Chem Soc
, vol.124
, pp. 4678-4684
-
-
Becker, D.A.1
Ley, J.J.2
Echegoyen, L.3
Alvarado, R.4
-
89
-
-
80052424406
-
L-NAME and l-arginine differentially ameliorate cigarette smoke-induced emphysema in mice
-
S.S. Valenca, C.R. Rueff-Barroso, W.A. Pimenta, A.C. Melo, R.T. Nesi, M.A. Silva, and L.C. Porto l-NAME and l-arginine differentially ameliorate cigarette smoke-induced emphysema in mice Pulm Pharmacol Ther 24 2011 587 594
-
(2011)
Pulm Pharmacol Ther
, vol.24
, pp. 587-594
-
-
Valenca, S.S.1
Rueff-Barroso, C.R.2
Pimenta, W.A.3
Melo, A.C.4
Nesi, R.T.5
Silva, M.A.6
Porto, L.C.7
-
90
-
-
80054696408
-
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice
-
M. Seimetz, N. Parajuli, A. Pichl, F. Veit, G. Kwapiszewska, F.C. Weisel, K. Milger, B. Egemnazarov, A. Turowska, and B. Fuchs Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice Cell 147 2011 293 305
-
(2011)
Cell
, vol.147
, pp. 293-305
-
-
Seimetz, M.1
Parajuli, N.2
Pichl, A.3
Veit, F.4
Kwapiszewska, G.5
Weisel, F.C.6
Milger, K.7
Egemnazarov, B.8
Turowska, A.9
Fuchs, B.10
-
91
-
-
73849130301
-
Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease
-
C. Brindicci, S.A. Kharitonov, M. Ito, M.W. Elliott, J.C. Hogg, P.J. Barnes, and K. Ito Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 181 2010 21 30
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 21-30
-
-
Brindicci, C.1
Kharitonov, S.A.2
Ito, M.3
Elliott, M.W.4
Hogg, J.C.5
Barnes, P.J.6
Ito, K.7
-
92
-
-
19444381651
-
Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB
-
Y. Li, W. Liu, G. Xing, C. Tian, Y. Zhu, and F. He Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB Cell Signal 17 2005 985 996
-
(2005)
Cell Signal
, vol.17
, pp. 985-996
-
-
Li, Y.1
Liu, W.2
Xing, G.3
Tian, C.4
Zhu, Y.5
He, F.6
-
93
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, and H. Ichijo Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1 EMBO J 17 1998 2596 2606
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
94
-
-
0029644240
-
Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B
-
J. Qin, G.M. Clore, W.M. Kennedy, J.R. Huth, and A.M. Gronenborn Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B Structure 3 1995 289 297
-
(1995)
Structure
, vol.3
, pp. 289-297
-
-
Qin, J.1
Clore, G.M.2
Kennedy, W.M.3
Huth, J.R.4
Gronenborn, A.M.5
-
95
-
-
19944404781
-
NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury
-
D.G. Souza, A.T. Vieira, V. Pinho, L.P. Sousa, A.A. Andrade, C.A. Bonjardim, M. McMillan, M. Kahn, and M.M. Teixeira NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury Br J Pharmacol 145 2005 246 254
-
(2005)
Br J Pharmacol
, vol.145
, pp. 246-254
-
-
Souza, D.G.1
Vieira, A.T.2
Pinho, V.3
Sousa, L.P.4
Andrade, A.A.5
Bonjardim, C.A.6
McMillan, M.7
Kahn, M.8
Teixeira, M.M.9
-
96
-
-
79955472293
-
Alleviation of oxidative stress by potent and selective thioredoxin-mimetic peptides
-
N. Bachnoff, M. Trus, and D. Atlas Alleviation of oxidative stress by potent and selective thioredoxin-mimetic peptides Free Radic Biol Med 50 2011 1355 1367
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 1355-1367
-
-
Bachnoff, N.1
Trus, M.2
Atlas, D.3
-
97
-
-
42449089433
-
Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice
-
A. Sato, Y. Hoshino, T. Hara, S. Muro, H. Nakamura, M. Mishima, and J. Yodoi Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice J Pharmacol Exp Ther 325 2008 380 388
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 380-388
-
-
Sato, A.1
Hoshino, Y.2
Hara, T.3
Muro, S.4
Nakamura, H.5
Mishima, M.6
Yodoi, J.7
|