Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 325, Issue 2, 2008, Pages 380-388

  Sato, Atsuyasu ^a,b   Hoshino, Yuma ^c   Hara, Tomijiro ^d   Muro, Shigeo ^a   Nakamura, Hajime ^c   Mishima, Michiaki ^a   Yodoi, Junji ^c,d  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Ako City Hospital   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; MACROPHAGE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; THIOREDOXIN 1; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; RECOMBINANT PROTEIN; THIOREDOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; EMPHYSEMA; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; GENETICS; HUMAN; IMMUNOLOGY; LUNG EMPHYSEMA; MACROPHAGE; METABOLISM; NEUTROPHIL; PATHOLOGY; SMOKE; TOBACCO; TRANSGENIC MOUSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINE CXCL2; HUMANS; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 12; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUTROPHILS; OXIDATIVE STRESS; PNEUMONIA; PULMONARY EMPHYSEMA; RECOMBINANT PROTEINS; RNA, MESSENGER; SMOKE; THIOREDOXINS; TOBACCO; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42449089433     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.134007     Document Type: Article

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