Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases

Biotechnology Progress

Volumn 28, Issue 3, 2012, Pages 814-823

  Carlage, Tyler ^a,b   Kshirsagar, Rashmi ^a   Zang, Li ^a   Janakiraman, Vijay ^a   Hincapie, Marina ^b   Lyubarskaya, Yelena ^a   Weiskopf, Andy ^a   Hancock, William S ^b  

^a BIOGEN   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Cell culture; Chinese hamster ovary; ITRAQ; Proteomics

Indexed keywords

ANTIAPOPTOTIC; BIOLOGICAL CHANGES; BIOLOGICAL PROCESS; CHINESE HAMSTER OVARY; CHINESE HAMSTER OVARY CELLS; CLUSTERIN; DYNAMIC ASPECTS; DYNAMIC CHANGES; EXPONENTIAL GROWTH PHASE; FED BATCHES; GROWTH MARKER; ISOMERASES; ITRAQ; MAMMALIAN CELL CULTURE; MOLECULAR CHAPERONES; PATHWAY ANALYSIS; PROTEIN EXPRESSIONS; PROTEOMICS; QUANTITATIVE PROTEOMICS; RECOMBINANT MONOCLONAL ANTIBODY; STATIONARY PHASE; STATIONARY PHASIS; TEMPORAL CHANGE; TUMOR PROLIFERATION; WESTERN BLOTTING;

BATCH CELL CULTURE; CELL CULTURE; CELL DEATH; CELL GROWTH; GENE EXPRESSION; GLYCOPROTEINS; GROWTH KINETICS; MOLECULAR BIOLOGY; MONOCLONAL ANTIBODIES;

RECOMBINANT PROTEINS;

PROTEIN BCL X; PROTEOME; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CHO CELL; CRICETULUS; GENETICS; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PROTEOMICS; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ANIMALS; BCL-X PROTEIN; BLOTTING, WESTERN; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; PROTEOME; PROTEOMICS; RECOMBINANT PROTEINS; TANDEM MASS SPECTROMETRY;

CRICETULUS GRISEUS; MAMMALIA;

EID: 84862169586     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1534     Document Type: Article

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