-
1
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB. (2004). Nuclear factor-kappaB: the enemy within. Cancer Cell 6: 203-208.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
2
-
-
4744351463
-
Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells
-
Antonyak MA, Miller AM, Jansen JM, Boehm JE, Balkman CE, Wakshlag JJ et al. (2004). Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells. J Biol Chem 279: 41461-41467.
-
(2004)
J Biol Chem
, vol.279
, pp. 41461-41467
-
-
Antonyak, M.A.1
Miller, A.M.2
Jansen, J.M.3
Boehm, J.E.4
Balkman, C.E.5
Wakshlag, J.J.6
-
3
-
-
33845489411
-
Two isoforms of tissue transglutaminase mediate opposing cellular fates
-
Antonyak MA, Jansen JM, Miller AM, Ly TK, Endo M, Cerione RA. (2006). Two isoforms of tissue transglutaminase mediate opposing cellular fates. Proc Natl Acad Sci USA 103: 18609-18614.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18609-18614
-
-
Antonyak, M.A.1
Jansen, J.M.2
Miller, A.M.3
Ly, T.K.4
Endo, M.5
Cerione, R.A.6
-
4
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB
-
Baldwin AS. (2001). Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB. J Clin Invest 107: 241-246.
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
5
-
-
0030846298
-
Tying it all together: Epigenetics, genetic, cell cycle, and cancer
-
Baylin SB. (1997). Tying it all together: epigenetics, genetic, cell cycle, and cancer. Science 277: 1948-1949.
-
(1997)
Science
, vol.277
, pp. 1948-1949
-
-
Baylin, S.B.1
-
6
-
-
2942590732
-
Exploiting tumour hypoxia in cancer treatment
-
Brown JM, Wilson WR. (2004). Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 4: 437-447.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 437-447
-
-
Brown, J.M.1
Wilson, W.R.2
-
7
-
-
0036889475
-
Oxygen deprivation induced cell death: An update
-
Brunelle JK, Chandel NS. (2002). Oxygen deprivation induced cell death: an update. Apoptosis 7: 475-482.
-
(2002)
Apoptosis
, vol.7
, pp. 475-482
-
-
Brunelle, J.K.1
Chandel, N.S.2
-
8
-
-
33750471197
-
Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: Molecular basis and biological significance
-
Bubici C, Papa S, Dean K, Franzoso G. (2006). Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance. Oncogene 25: 6731-6748.
-
(2006)
Oncogene
, vol.25
, pp. 6731-6748
-
-
Bubici, C.1
Papa, S.2
Dean, K.3
Franzoso, G.4
-
9
-
-
17844391272
-
Chemistry and biology of dihydroisoxazole derivatives: Selective inhibitors of human transglutaminase 2
-
Choi K, Siegel M, Piper JL, Yuan L, Cho E, Strnad P et al. (2005). Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2. Chem Biol 12: 469-475.
-
(2005)
Chem Biol
, vol.12
, pp. 469-475
-
-
Choi, K.1
Siegel, M.2
Piper, J.L.3
Yuan, L.4
Cho, E.5
Strnad, P.6
-
10
-
-
0030968939
-
Targeting gene expression to hypoxic tumor cells
-
Dachs GU, Patterson AV, Firth JD, Ratcliffe PJ, Townsend KM, Stratford IJ et al. (1997). Targeting gene expression to hypoxic tumor cells. Nat Med 3: 515-520.
-
(1997)
Nat Med
, vol.3
, pp. 515-520
-
-
Dachs, G.U.1
Patterson, A.V.2
Firth, J.D.3
Ratcliffe, P.J.4
Townsend, K.M.5
Stratford, I.J.6
-
11
-
-
0034747685
-
Gene disruption of tissue transglutaminase
-
De Laurenzi V, Melino G. (2001). Gene disruption of tissue transglutaminase. Mol Cell Biol 21: 148-155.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 148-155
-
-
De Laurenzi, V.1
Melino, G.2
-
12
-
-
1642524964
-
Measurement of oxidative stress in cells exposed to hypoxia and other changes in oxygen concentration
-
Dirmeier R, O'Brien K, Engle M, Dodd A, Spears E, Poyton RO. (2004). Measurement of oxidative stress in cells exposed to hypoxia and other changes in oxygen concentration. Methods Enzymol 381: 589-603.
-
(2004)
Methods Enzymol
, vol.381
, pp. 589-603
-
-
Dirmeier, R.1
O'Brien, K.2
Engle, M.3
Dodd, A.4
Spears, E.5
Poyton, R.O.6
-
13
-
-
0036804796
-
Transglutaminase 2: An enigmatic enzyme with diverse functions
-
Fesus L, Piacentini M. (2002). Transglutaminase 2: an enigmatic enzyme with diverse functions. Trends Biochem Sci 27: 534-539.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 534-539
-
-
Fesus, L.1
Piacentini, M.2
-
14
-
-
48749092910
-
Transglutaminase 2 protects against ischemic insult, interacts with HIF1b, and attenuates HIF1 signaling
-
Filiano AJ, Bailey CDC, Tucholski J, Gundemir S, Johnson GVW. (2008). Transglutaminase 2 protects against ischemic insult, interacts with HIF1b, and attenuates HIF1 signaling. FASEB J 22: 2662-2675.
-
(2008)
FASEB J
, vol.22
, pp. 2662-2675
-
-
Filiano, A.J.1
Bailey, C.D.C.2
Tucholski, J.3
Gundemir, S.4
Johnson, G.V.W.5
-
16
-
-
0042068233
-
A novel function of tissue-type transglutaminase: Protein disulphide isomerase
-
Hasegawa G, Suwa M, Ichikawa Y, Ohtsuka T, Kumagai S, Kikuchi M et al. (2003). A novel function of tissue-type transglutaminase: protein disulphide isomerase. Biochem J 373: 793-803.
-
(2003)
Biochem J
, vol.373
, pp. 793-803
-
-
Hasegawa, G.1
Suwa, M.2
Ichikawa, Y.3
Ohtsuka, T.4
Kumagai, S.5
Kikuchi, M.6
-
17
-
-
33646858986
-
Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells
-
Herman JF, Mangala LS, Mehta K. (2006). Implications of increased tissue transglutaminase (TG2) expression in drug-resistant breast cancer (MCF-7) cells. Oncogene 25: 3049-3058.
-
(2006)
Oncogene
, vol.25
, pp. 3049-3058
-
-
Herman, J.F.1
Mangala, L.S.2
Mehta, K.3
-
18
-
-
33645835678
-
Calcium signaling stimulates translation of HIF-alpha during hypoxia
-
Hui AS, Bauer AL, Striet JB, Schnell PO, Czyzyk-Krzeska MF. (2006). Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J 20: 466-475.
-
(2006)
FASEB J
, vol.20
, pp. 466-475
-
-
Hui, A.S.1
Bauer, A.L.2
Striet, J.B.3
Schnell, P.O.4
Czyzyk-Krzeska, M.F.5
-
19
-
-
0037448439
-
Differential incorporation of biotinylated polyamines by transglutaminase 2
-
Jeon JH, Kim CW, Shin DM, Kim K, Cho SY, Kwon JC et al. (2003a). Differential incorporation of biotinylated polyamines by transglutaminase 2. FEBS Lett 534: 180-184.
-
(2003)
FEBS Lett
, vol.534
, pp. 180-184
-
-
Jeon, J.H.1
Kim, C.W.2
Shin, D.M.3
Kim, K.4
Cho, S.Y.5
Kwon, J.C.6
-
20
-
-
0141864664
-
Transglutaminase 2 inhibits Rb binding of human papillomavirus E7 by incorporating polyamine
-
Jeon JH, Choi KH, Cho SY, Kim CW, Shin DM, Kwon JC et al. (2003b). Transglutaminase 2 inhibits Rb binding of human papillomavirus E7 by incorporating polyamine. EMBO J 22: 5273-5282.
-
(2003)
EMBO J
, vol.22
, pp. 5273-5282
-
-
Jeon, J.H.1
Choi, K.H.2
Cho, S.Y.3
Kim, C.W.4
Shin, D.M.5
Kwon, J.C.6
-
21
-
-
12344314006
-
Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine
-
Jeon JH, Lee HJ, Jang GY, Kim CW, Shin DM, Cho SY et al. (2004). Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine. Exp Mol Med 36: 576-581.
-
(2004)
Exp Mol Med
, vol.36
, pp. 576-581
-
-
Jeon, J.H.1
Lee, H.J.2
Jang, G.Y.3
Kim, C.W.4
Shin, D.M.5
Cho, S.Y.6
-
22
-
-
33746123520
-
Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia
-
Kaidi A, Qualtrough D, Williams AC, Paraskeva C. (2006). Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia. Cancer Res 66: 6683-6691.
-
(2006)
Cancer Res
, vol.66
, pp. 6683-6691
-
-
Kaidi, A.1
Qualtrough, D.2
Williams, A.C.3
Paraskeva, C.4
-
23
-
-
44449174536
-
Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia
-
Kuhlicke J, Frick JS, Morote-Garcia JC, Rosenberger P, Eltzschig HK. (2007). Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia. PLos ONE 2: e1364.
-
(2007)
PLos ONE
, vol.2
-
-
Kuhlicke, J.1
Frick, J.S.2
Morote-Garcia, J.C.3
Rosenberger, P.4
Eltzschig, H.K.5
-
26
-
-
0037317032
-
Transglutaminases: Crosslinking enzymes with pleiotropic functions
-
Lorand L, Graham RM. (2003). Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 4: 140-156.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 140-156
-
-
Lorand, L.1
Graham, R.M.2
-
27
-
-
24344488419
-
The HIF pathway in cancer
-
Maxwell PH. (2005). The HIF pathway in cancer. Semin Cell Dev Biol 16: 523-530.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 523-530
-
-
Maxwell, P.H.1
-
28
-
-
9744274000
-
Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer
-
Mehta K, Fok J, Miller FR, Koul D, Sahin AA. (2004). Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer. Clin Cancer Res 10: 8068-8076.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8068-8076
-
-
Mehta, K.1
Fok, J.2
Miller, F.R.3
Koul, D.4
Sahin, A.A.5
-
29
-
-
2642536093
-
Tissue transglutaminase has intrinsic kinase activity: Identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase
-
Mishra S, Murphy LJ. (2004). Tissue transglutaminase has intrinsic kinase activity: identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase. J Biol Chem 279: 23863-23868.
-
(2004)
J Biol Chem
, vol.279
, pp. 23863-23868
-
-
Mishra, S.1
Murphy, L.J.2
-
30
-
-
33845951183
-
Transglutaminase 2 mediates polymer formation of ItcBa through C-terminal glutamine cluster
-
Park SS, Kim JM, Kim DS, Kim IH, Kim SY. (2006). Transglutaminase 2 mediates polymer formation of ItcBa through C-terminal glutamine cluster. J Biol Chem 281: 34965-34972.
-
(2006)
J Biol Chem
, vol.281
, pp. 34965-34972
-
-
Park, S.S.1
Kim, J.M.2
Kim, D.S.3
Kim, I.H.4
Kim, S.Y.5
-
31
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
Perkins ND. (2007). Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8: 49-62.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 49-62
-
-
Perkins, N.D.1
-
33
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. (2006). Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441: 437-443.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
34
-
-
33745863017
-
Drug insight: Cancer therapy strategies based on restoration of endogenous cell death mechanisms
-
Reed JC. (2006). Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms. Nat Clin Pract Oncol 3: 388-398.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 388-398
-
-
Reed, J.C.1
-
35
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. (2003). Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
36
-
-
2442607838
-
Cell type-specific activation of intracellular transglutaminase 2 by oxidative stress or ultraviolet irradiation: Implications of transglutami-nase 2 in age-related cataractogenesis
-
Shin DM, Jeon JH, Kim CW, Cho SY, Kwon JC, Lee HJ et al. (2004). Cell type-specific activation of intracellular transglutaminase 2 by oxidative stress or ultraviolet irradiation: implications of transglutami-nase 2 in age-related cataractogenesis. J Biol Chem 279: 15032-15039.
-
(2004)
J Biol Chem
, vol.279
, pp. 15032-15039
-
-
Shin, D.M.1
Jeon, J.H.2
Kim, C.W.3
Cho, S.Y.4
Kwon, J.C.5
Lee, H.J.6
-
37
-
-
46749089164
-
TGFb mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation
-
Shin DM, Jeon JH, Kim CW, Cho SY, Lee HJ, Jang GY et al. (2008). TGFb mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation. FASEB J 22: 2498-2507.
-
(2008)
FASEB J
, vol.22
, pp. 2498-2507
-
-
Shin, D.M.1
Jeon, J.H.2
Kim, C.W.3
Cho, S.Y.4
Lee, H.J.5
Jang, G.Y.6
-
38
-
-
0037252190
-
Novel transglutaminase inhibitors reverse the inflammation of allergic conjunctivitis
-
Sohn J, Kim TI, Yoon YH, Kim JY, Kim SY. (2003). Novel transglutaminase inhibitors reverse the inflammation of allergic conjunctivitis. J Clin Invest 111: 121-128.
-
(2003)
J Clin Invest
, vol.111
, pp. 121-128
-
-
Sohn, J.1
Kim, T.I.2
Yoon, Y.H.3
Kim, J.Y.4
Kim, S.Y.5
-
39
-
-
34548848815
-
Tissue transglutaminase-mediated chemoresistance in cancer cells
-
DOI 10.1016/j.drup.2007.06.002, PII S1368764607000428
-
Verma A, Mehta K. (2007). Tissue transglutaminase-mediated chemoresistance in cancer cells. Drug Resist Updat 10: 144-151. (Pubitemid 47446401)
-
(2007)
Drug Resistance Updates
, vol.10
, Issue.4-5
, pp. 144-151
-
-
Verma, A.1
Mehta, K.2
-
40
-
-
0034649507
-
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
-
Wykoff CC, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. (2000). Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene 19: 6297-6305.
-
(2000)
Oncogene
, vol.19
, pp. 6297-6305
-
-
Wykoff, C.C.1
Pugh, C.W.2
Maxwell, P.H.3
Harris, A.L.4
Ratcliffe, P.J.5
-
41
-
-
30644459554
-
Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells
-
Yamaguchi H, Wang HG. (2006). Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells. Mol Cell Biol 26: 569-579.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 569-579
-
-
Yamaguchi, H.1
Wang, H.G.2
-
42
-
-
33644668017
-
Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas
-
Yuan L, Choi K, Khosla C, Zheng X, Higashikubo R, Chicoine MR et al. (2005). Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. Mol Cancer Ther 4: 1293-1302.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1293-1302
-
-
Yuan, L.1
Choi, K.2
Khosla, C.3
Zheng, X.4
Higashikubo, R.5
Chicoine, M.R.6
-
43
-
-
0034213146
-
Expression of hypoxia-inducible factor 1alpha in brain tumors: Association with angiogenesis, invasion, and progression
-
Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL. (2000). Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88: 2606-2618.
-
(2000)
Cancer
, vol.88
, pp. 2606-2618
-
-
Zagzag, D.1
Zhong, H.2
Scalzitti, J.M.3
Laughner, E.4
Simons, J.W.5
Semenza, G.L.6
-
44
-
-
0038326942
-
Identification of differentially expressed proteins in human glioblastoma cell lines and tumors
-
Zhang R, Tremblay TL, McDermid A, Thibault P, Stanimirovic D. (2003a). Identification of differentially expressed proteins in human glioblastoma cell lines and tumors. Glia 42: 194-208.
-
(2003)
Glia
, vol.42
, pp. 194-208
-
-
Zhang, R.1
Tremblay, T.L.2
McDermid, A.3
Thibault, P.4
Stanimirovic, D.5
-
45
-
-
0038285657
-
COX-2-dependent cardiac failure in Gh/tTG transgenic mice
-
Zhang Z, Vezza R, Plappert T, McNamara P, Lawson JA, Austin S et al. (2003b). COX-2-dependent cardiac failure in Gh/tTG transgenic mice. Circ Res 92: 1153-1161.
-
(2003)
Circ Res
, vol.92
, pp. 1153-1161
-
-
Zhang, Z.1
Vezza, R.2
Plappert, T.3
McNamara, P.4
Lawson, J.A.5
Austin, S.6
|