Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: A cis-prenyltransferase for bacterial peptidoglycan biosynthesis

Bioorganic Chemistry

Volumn 43, Issue , 2012, Pages 51-57

  Teng, Kuo Hsun ^a   Liang, Po Huang ^a  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

Conformational change; Inhibitor; Isoprenoid; Pre steady state kinetics; Prenyltransferase; X ray structure

Indexed keywords

AROMATIC PRENYLTRANSFERASE; BISPHOSPHONIC ACID DERIVATIVE; DIHYDROPYRIDIN 2 ONE DERIVATIVE; DIMETHYLALLYLTRANSFERASE; FARNESYL DIPHOSPHATE; GERANYLGERANYLTRANSFERASE; HTS 04781; ISOPENTENYL DIPHOSPHATE; PEPTIDOGLYCAN; PROTEIN FARNESYLTRANSFERASE; SQUALENE SYNTHASE; TETRAMIC ACID DERIVATIVE; TETRONIC ACID DERIVATIVE; TRANSFERASE; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; UNDECAPRENYL DIPHOSPHATE SYNTHASE;

CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME KINETICS; ENZYME STRUCTURE; HIGH THROUGHPUT SCREENING; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW;

ALKYL AND ARYL TRANSFERASES; BACTERIA; HEMITERPENES; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDOGLYCAN; POLYISOPRENYL PHOSPHATES; PROTEIN STRUCTURE, TERTIARY; SESQUITERPENES; TERPENES; TRANSFERASES;

BACTERIA (MICROORGANISMS);

EID: 84862024512     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2011.09.004     Document Type: Review

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