The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 34, 2009, Pages 14309-14314

  Metzger, Ute ^a   Schall, Christoph ^a   Zocher, Georg ^a   Unsöld, Inge ^a   Stec, Edyta ^b   Li, Shu Ming ^b   Heide, Lutz ^a   Stehle, Thilo ^a,c  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ABBA prenyltransferase; EC 2.5.1.34; Ergot alkaloids; PT barrel

Indexed keywords

BACTERIAL ENZYME; DIMETHYLALLYLTRANSFERASE; DIMETHYLALLYLTRYPTOPHAN SYNTHASE; ERGOT ALKALOID; INDOLE; MAGNESIUM; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FUMIGATUS; BACTERIUM; CATALYSIS; ENZYME MECHANISM; FUNGUS; GENOME; PRENYLATION; PRIORITY JOURNAL; X RAY ANALYSIS;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; ASPERGILLUS FUMIGATUS; BACTERIA; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMETHYLALLYLTRANSTRANSFERASE; FUNGAL PROTEINS; FUNGI; HEMITERPENES; MAGNESIUM; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; ORGANOPHOSPHORUS COMPOUNDS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TERPENES; TRYPTOPHAN;

ASPERGILLUS FUMIGATUS; BACTERIA (MICROORGANISMS); FUNGI;

EID: 70149099367     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904897106     Document Type: Article

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