Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 734, Issue 1-2, 2012, Pages 20-29

  Wang, Yu ^a   Liu, Qiao ^a   Liu, Zhaojian ^a   Li, Boxuan ^a   Sun, Zhaoliang ^a   Zhou, Haibin ^a   Zhang, Xiyu ^a   Gong, Yaoqin ^a   Shao, Changshun ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

ATM; Berberine; Chk1; G2 M arrest; P53

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; 7 HYDROXYSTAUROSPORINE; ATM PROTEIN; BERBERINE; CHECKPOINT KINASE 1; PROTEIN P51; PROTEIN P53;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG EXPOSURE; ENZYME INHIBITION; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BERBERINE; CELL CYCLE CHECKPOINTS; CELL DIVISION; CELL LINE, TUMOR; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; G2 PHASE; MALE; MICE; MITOSIS; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 84862006905     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2012.04.005     Document Type: Article

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