ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

EMBO Journal

Volumn 24, Issue 19, 2005, Pages 3411-3422

  Chen, Lihong ^a   Gilkes, Daniele M ^a   Pan, Yu ^a   Lane, William S ^b   Chen, Jiandong ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

ATM; Chk2; MDM2; MDMX; p53

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; PROTEIN MDMX; PROTEIN P53;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UBIQUITINATION;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA DAMAGE; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 27144444111     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600812     Document Type: Article

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