메뉴 건너뛰기




Volumn 34, Issue 5, 2009, Pages 1221-1230

Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells

Author keywords

Apoptosis; Berberine; p53; Prostate cancer cells

Indexed keywords

BERBERINE; CASPASE 3; CISPLATIN; PIFITHRIN ALPHA; PROTEIN BAX; PROTEIN P53; SMALL INTERFERING RNA;

EID: 67649438659     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000250     Document Type: Article
Times cited : (111)

References (45)
  • 1
    • 0033980370 scopus 로고    scopus 로고
    • Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents
    • Kelloff GJ, Crowell JA, Steele VE, et al: Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J Nutr 130: 467-471, 2000.
    • (2000) J Nutr , vol.130 , pp. 467-471
    • Kelloff, G.J.1    Crowell, J.A.2    Steele, V.E.3
  • 2
    • 0031444312 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
    • Ahmad N, Feyes DK, Nieminen AL, Agarwal R and Mukhtar H: Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 89: 1881-1886, 1997.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1881-1886
    • Ahmad, N.1    Feyes, D.K.2    Nieminen, A.L.3    Agarwal, R.4    Mukhtar, H.5
  • 3
    • 0032955675 scopus 로고    scopus 로고
    • Modulating apoptosis: Current applications and prospects for future drug development
    • Deigner HP and Kinscherf R: Modulating apoptosis: current applications and prospects for future drug development. Curr Med Chem 6: 399-414, 1999.
    • (1999) Curr Med Chem , vol.6 , pp. 399-414
    • Deigner, H.P.1    Kinscherf, R.2
  • 4
    • 0034121281 scopus 로고    scopus 로고
    • Cell cycle molecular targets in novel anticancer drug discovery
    • Buolamwini JK: Cell cycle molecular targets in novel anticancer drug discovery. Curr Pharm Des 6: 379-392, 2000.
    • (2000) Curr Pharm Des , vol.6 , pp. 379-392
    • Buolamwini, J.K.1
  • 5
    • 0034183775 scopus 로고    scopus 로고
    • Cell cycle control as a basis for cancer drug development
    • McDonald ER and El-Deiry WS: Cell cycle control as a basis for cancer drug development. Int J Oncol 16: 871-886, 2000.
    • (2000) Int J Oncol , vol.16 , pp. 871-886
    • McDonald, E.R.1    El-Deiry, W.S.2
  • 6
    • 0027213657 scopus 로고
    • Pharmacological studies on antidiarrheal effects of berberine and geranin herb
    • Takase H, Yamamoto K, Ito K and Yumioka E: Pharmacological studies on antidiarrheal effects of berberine and geranin herb. Nippon Yakurigaku Zasshi 2: 101-112, 1993.
    • (1993) Nippon Yakurigaku Zasshi , vol.2 , pp. 101-112
    • Takase, H.1    Yamamoto, K.2    Ito, K.3    Yumioka, E.4
  • 8
    • 0346724714 scopus 로고    scopus 로고
    • The anti-inflammatory potential of berberine in vitro and in vivo
    • Kuo CL, Chi CW and Liu TY: The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett 203: 127-137, 2004.
    • (2004) Cancer Lett , vol.203 , pp. 127-137
    • Kuo, C.L.1    Chi, C.W.2    Liu, T.Y.3
  • 9
    • 27944439037 scopus 로고
    • Pharmacological studies on metabolism of cancer tissues: Pharmacological studies on carcinostatic effects of some plant components and their derivatives
    • Hano K: Pharmacological studies on metabolism of cancer tissues: pharmacological studies on carcinostatic effects of some plant components and their derivatives. Gann 48: 443-450, 1957.
    • (1957) Gann , vol.48 , pp. 443-450
    • Hano, K.1
  • 10
  • 11
    • 0032985993 scopus 로고    scopus 로고
    • Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells
    • Fukuda K, Hibiya Y, Mutoh M, Koshiji M, Akao S and Fujiwara H: Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol 2: 227-233, 1999.
    • (1999) J Ethnopharmacol , vol.2 , pp. 227-233
    • Fukuda, K.1    Hibiya, Y.2    Mutoh, M.3    Koshiji, M.4    Akao, S.5    Fujiwara, H.6
  • 12
    • 0032617444 scopus 로고    scopus 로고
    • Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells
    • Lin JG, Chung JG and Wu LT: Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells. Am J Chin Med 27: 265-275, 1999.
    • (1999) Am J Chin Med , vol.27 , pp. 265-275
    • Lin, J.G.1    Chung, J.G.2    Wu, L.T.3
  • 13
    • 0037245495 scopus 로고    scopus 로고
    • Mode of binding of the cytotoxic alkaloid berberine with the double helix oligonucleotide d(AAGAATTCTT)(2)
    • Mazzini S, Bellucci MC and Mondelli R: Mode of binding of the cytotoxic alkaloid berberine with the double helix oligonucleotide d(AAGAATTCTT)(2). Bioorg Med Chem 11: 505-514, 2003.
    • (2003) Bioorg Med Chem , vol.11 , pp. 505-514
    • Mazzini, S.1    Bellucci, M.C.2    Mondelli, R.3
  • 14
    • 27744558555 scopus 로고    scopus 로고
    • Synthesis, DNA-binding affinities, and binding mode of berberine dimmers
    • Qin Y, Pang JY, Chen WH, Cai Z and Jiang ZH: Synthesis, DNA-binding affinities, and binding mode of berberine dimmers. Bioorg Med Chem 14: 25-32, 2006.
    • (2006) Bioorg Med Chem , vol.14 , pp. 25-32
    • Qin, Y.1    Pang, J.Y.2    Chen, W.H.3    Cai, Z.4    Jiang, Z.H.5
  • 15
    • 1642576322 scopus 로고    scopus 로고
    • A fluorescent intercalator displacement assay for establishing DNA binding selectivity and affinity
    • Tse WC and Boger DL: A fluorescent intercalator displacement assay for establishing DNA binding selectivity and affinity. Acc Chem Res 37: 61-69, 2004.
    • (2004) Acc Chem Res , vol.37 , pp. 61-69
    • Tse, W.C.1    Boger, D.L.2
  • 16
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu LF: DNA topoisomerase poisons as antitumor drugs. Ann Rev Biochem 58: 351-375, 1989.
    • (1989) Ann Rev Biochem , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 17
    • 0033992478 scopus 로고    scopus 로고
    • p53 and human cancer: The first ten thousand mutations
    • Hainaut P and Hollstein M: p53 and human cancer: the first ten thousand mutations. Adv Cancer Res 77: 81-137, 2000.
    • (2000) Adv Cancer Res , vol.77 , pp. 81-137
    • Hainaut, P.1    Hollstein, M.2
  • 18
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response p53
    • Vousden KH and Lu X: Live or let die: the cell's response p53. Nat Rev Cancer 2: 594-604, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 20
    • 0036479115 scopus 로고    scopus 로고
    • Transcriptional repression of the anti-apoptotic survivin gene by wild-type p53
    • Hoffman WH, Biade S, Zilfou JT, Chen J and Murphy M: Transcriptional repression of the anti-apoptotic survivin gene by wild-type p53. J Biol Chem 277: 3247-3257, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 3247-3257
    • Hoffman, W.H.1    Biade, S.2    Zilfou, J.T.3    Chen, J.4    Murphy, M.5
  • 21
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell-death
    • Olitvai ZN, Milliman CL and Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell-death. Cell 74: 609-619, 1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Olitvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 22
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X: The expanding role of mitochondria in apoptosis. Genes Dev 15: 2922-2933, 2001.
    • (2001) Genes Dev , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 23
    • 34247400267 scopus 로고    scopus 로고
    • Curcumin induces G(2)/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK
    • Weir NM, Selvendiran K, Kutala VK, et al: Curcumin induces G(2)/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK. Cancer Biol Ther 6: 178-184, 2007.
    • (2007) Cancer Biol Ther , vol.6 , pp. 178-184
    • Weir, N.M.1    Selvendiran, K.2    Kutala, V.K.3
  • 24
    • 0037159575 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells
    • Kuo PL, Chiang LC and Lin CC: Resveratrol-induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells. Life Sci 72: 23-34, 2002.
    • (2002) Life Sci , vol.72 , pp. 23-34
    • Kuo, P.L.1    Chiang, L.C.2    Lin, C.C.3
  • 25
    • 0043067996 scopus 로고    scopus 로고
    • Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells
    • Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML and Mukhtar H: Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene 22: 4851-4859, 2003.
    • (2003) Oncogene , vol.22 , pp. 4851-4859
    • Hastak, K.1    Gupta, S.2    Ahmad, N.3    Agarwal, M.K.4    Agarwal, M.L.5    Mukhtar, H.6
  • 26
    • 0842304283 scopus 로고    scopus 로고
    • Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: Implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
    • Ito K, Nakazato T, Yamato K, et al: Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species. Cancer Res 64: 1071-1078, 2004.
    • (2004) Cancer Res , vol.64 , pp. 1071-1078
    • Ito, K.1    Nakazato, T.2    Yamato, K.3
  • 27
    • 0037027759 scopus 로고    scopus 로고
    • Inhibitory effect of glycolic acid on ultraviolet B-induced c-fos expression, AP-1 activation and p53-p21 response in a human keratinocyte cell line
    • Ahn KS, Park KS, Jung KM, et al: Inhibitory effect of glycolic acid on ultraviolet B-induced c-fos expression, AP-1 activation and p53-p21 response in a human keratinocyte cell line. Cancer Lett 186: 125-135, 2002.
    • (2002) Cancer Lett , vol.186 , pp. 125-135
    • Ahn, K.S.1    Park, K.S.2    Jung, K.M.3
  • 28
    • 33847368594 scopus 로고    scopus 로고
    • Inhibitory effect of snake venom toxin from Vipera lebetina turanica on hormone-refractory human prostate cancer cell growth: Induction of apoptosis through inactivation of nuclear factor kappaB
    • Son DJ, Park MH, Chae SJ, et al: Inhibitory effect of snake venom toxin from Vipera lebetina turanica on hormone-refractory human prostate cancer cell growth: induction of apoptosis through inactivation of nuclear factor kappaB. Mol Cancer Ther 6: 675-683, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 675-683
    • Son, D.J.1    Park, M.H.2    Chae, S.J.3
  • 29
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 31
    • 31144440676 scopus 로고    scopus 로고
    • Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line
    • Lin JP, Yang JS, Lee JH, Hsieh WT and Chung JG: Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. World J Gastroenterol 12: 21-28, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 21-28
    • Lin, J.P.1    Yang, J.S.2    Lee, J.H.3    Hsieh, W.T.4    Chung, J.G.5
  • 32
    • 33748924524 scopus 로고    scopus 로고
    • Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase-3 and PARP
    • Mantena SK, Sharma SD and Katiyar SK: Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase-3 and PARP. Carcinogenesis 27: 2018-2027, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 2018-2027
    • Mantena, S.K.1    Sharma, S.D.2    Katiyar, S.K.3
  • 33
    • 33644984254 scopus 로고    scopus 로고
    • Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells
    • Mantena SK, Sharma SD and Katiyar SK: Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther 5: 296-308, 2006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 296-308
    • Mantena, S.K.1    Sharma, S.D.2    Katiyar, S.K.3
  • 35
    • 0028927179 scopus 로고
    • P53, cell cycle control and apoptosis: Implications for cancer
    • Kastan MB, Canman CE and Leonard CJ: P53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev 14: 3-15, 1995.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 36
    • 0035863397 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3
    • Jiang XH, Wong BC, Yuen St, et al: Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. Int J Cancer 91: 173-179, 2001.
    • (2001) Int J Cancer , vol.91 , pp. 173-179
    • Jiang, X.H.1    Wong, B.C.2    Yuen, S.3
  • 37
    • 17444408529 scopus 로고    scopus 로고
    • Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells
    • Li TM, Chen GW, Su CC, Lin JG, Yeh CC, Cheng KC and Chung JG: Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells. Anticancer Res 25: 971-979, 2005.
    • (2005) Anticancer Res , vol.25 , pp. 971-979
    • Li, T.M.1    Chen, G.W.2    Su, C.C.3    Lin, J.G.4    Yeh, C.C.5    Cheng, K.C.6    Chung, J.G.7
  • 38
    • 33745967219 scopus 로고    scopus 로고
    • Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo
    • Hsu YL, Cho CY, Kuo PL, Huang YT and Lin CC: Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. J Pharmacol Exp Ther 318: 484-494, 2006.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 484-494
    • Hsu, Y.L.1    Cho, C.Y.2    Kuo, P.L.3    Huang, Y.T.4    Lin, C.C.5
  • 39
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • Molinari M: Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif 33: 261-274, 2000.
    • (2000) Cell Prolif , vol.33 , pp. 261-274
    • Molinari, M.1
  • 40
    • 33845219352 scopus 로고    scopus 로고
    • Berberine induces apoptosis through a mitochondrial/caspase pathway in human promonocytic U937 cells
    • Jantova S, Cipak L and Letasiova S: Berberine induces apoptosis through a mitochondrial/caspase pathway in human promonocytic U937 cells. Toxicol In Vitro 21: 25-31, 2007.
    • (2007) Toxicol In Vitro , vol.21 , pp. 25-31
    • Jantova, S.1    Cipak, L.2    Letasiova, S.3
  • 41
    • 32144452226 scopus 로고    scopus 로고
    • Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3
    • Lin CC, Kao ST, Chen GW, Ho HC and Chung JG: Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. Anticancer Res 26: 227-242, 2006.
    • (2006) Anticancer Res , vol.26 , pp. 227-242
    • Lin, C.C.1    Kao, S.T.2    Chen, G.W.3    Ho, H.C.4    Chung, J.G.5
  • 42
    • 31144436796 scopus 로고    scopus 로고
    • Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells
    • Hwang JM, Kuo HC, Tseng TH, Liu JY and Chu CY: Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells. Arch Toxicol 80: 62-73, 2006.
    • (2006) Arch Toxicol , vol.80 , pp. 62-73
    • Hwang, J.M.1    Kuo, H.C.2    Tseng, T.H.3    Liu, J.Y.4    Chu, C.Y.5
  • 43
    • 0000368040 scopus 로고    scopus 로고
    • Intermittent androgen suppression for prostate cancer: Rationale and clinical experience
    • Gleave M, Goldenberg SL, Bruchovsky N and Rennie P: Intermittent androgen suppression for prostate cancer: rationale and clinical experience. Prostate Cancer Prostatic Dis 1: 289-296, 1998.
    • (1998) Prostate Cancer Prostatic Dis , vol.1 , pp. 289-296
    • Gleave, M.1    Goldenberg, S.L.2    Bruchovsky, N.3    Rennie, P.4
  • 44
    • 33947590535 scopus 로고    scopus 로고
    • Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines
    • Ivanov NI, Cowell SP, Brown P, Rennie PS, Guns ES and Cox ME: Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines. Clin Nutr 26: 252-263, 2007.
    • (2007) Clin Nutr , vol.26 , pp. 252-263
    • Ivanov, N.I.1    Cowell, S.P.2    Brown, P.3    Rennie, P.S.4    Guns, E.S.5    Cox, M.E.6
  • 45
    • 33745184934 scopus 로고    scopus 로고
    • Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines
    • Maria McCrohan A, Morrissey C, O'Keane C, et al: Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines. Cancer 106: 2743-2752, 2006.
    • (2006) Cancer , vol.106 , pp. 2743-2752
    • Maria McCrohan, A.1    Morrissey, C.2    O'Keane, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.