Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats

Journal of Ethnopharmacology

Volumn 142, Issue 1, 2012, Pages 121-128

  Yao, Hsien Tsung ^a   Chang, Yi Wei ^b   Uramaru, Naoto ^c   Watanabe, Yoko ^c   Kitamura, Shigeyuki ^c   Kuo, Yueh Hsiung ^a   Lii, Chong Kuei ^a   Yeh, Teng Kuang ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bu Zhong Yi Qi Tang; Drug metabolizing enzymes; Rats; Tolbutamide; Traditional Chinese medicines

Indexed keywords

BU ZHONG YI QI TANG; CYTOCHROME P450 2C; CYTOCHROME P450 2C11; DICLOFENAC; DRUG METABOLIZING ENZYME; GLUCOSE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE DISULFIDE; GLUTATHIONE TRANSFERASE; TOLBUTAMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CATALYSIS; CONTROLLED STUDY; DIET; DRUG BLOOD LEVEL; DRUG EFFECT; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYDROXYLATION; IMMUNOBLOTTING; LIPID PEROXIDATION; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NONHUMAN; RAT;

ANIMALS; BLOOD GLUCOSE; CYTOCHROME P-450 ENZYME SYSTEM; DIET, HIGH-FAT; DRUGS, CHINESE HERBAL; ENZYME INHIBITORS; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; HYPOGLYCEMIC AGENTS; LIPID PEROXIDATION; LIVER; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; TOLBUTAMIDE;

RATTUS; RATTUS NORVEGICUS;

EID: 84861960190     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.04.024     Document Type: Article

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