Persistent Induction of Hepatic and Pulmonary Phase II Enzymes by 3-Methylcholanthrene in Rats

Toxicological Sciences

Volumn 102, Issue 2, 2008, Pages 337-344

  Kondraganti, Sudha R ^a   Jiang, Weiwu ^a   Jaiswal, Anil K ^b   Moorthy, Bhagavatula ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

3 methylcholanthrene; Ah receptor; Carcinogenesis; CYP1A1; CYP1B1; Gene expression; In vivo; NAD(P)H:quinone oxidoreductase; Phase II enzymes; Rat

Indexed keywords

3 METHYLCHOLANTHRENE; CYTOCHROME P450 1A; CYTOCHROME P450 1B1; GLUCURONOSYLTRANSFERASE 1A1; GLUTATHIONE TRANSFERASE ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; POLYCYCLIC AROMATIC HYDROCARBON; URIDINE DIPHOSPHATE;

ARTICLE; CHEMICAL CARCINOGENESIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME METABOLISM; GENE EXPRESSION REGULATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; RAT; SPRAGUE DAWLEY RAT;

ALDEHYDE DEHYDROGENASE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; ENZYME INDUCTION; EPOXIDE HYDROLASES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; INJECTIONS, INTRAPERITONEAL; ISOENZYMES; LIVER; LUNG; METABOLIC DETOXICATION, PHASE II; METHYLCHOLANTHRENE; MICROSOMES, LIVER; NAD(P)H DEHYDROGENASE (QUINONE); RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER;

RATTUS;

EID: 40949128665     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn007     Document Type: Article

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