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Volumn 302, Issue 11, 2012, Pages

NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone

Author keywords

Reactive oxygen species; Vascular tone

Indexed keywords

REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 84861765821     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00780.2011     Document Type: Review
Times cited : (59)

References (196)
  • 2
    • 0028902704 scopus 로고
    • Potentiation of the hypoxic contraction of guineapig isolated pulmonary arteries by two inhibitors of superoxide dismutase
    • Abdalla S, Will JA. Potentiation of the hypoxic contraction of guineapig isolated pulmonary arteries by two inhibitors of superoxide dismutase. Gen Pharmacol 26: 785-792, 1995.
    • (1995) Gen Pharmacol , vol.26 , pp. 785-792
    • Abdalla, S.1    Will, J.A.2
  • 4
    • 33751562718 scopus 로고    scopus 로고
    • Increased expression of gp 91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: Involvement of the reninangiotensin system
    • Akasaki T, Ohya Y, Kuroda J, Eto K, Abe I, Sumimoto H, lida M. Increased expression of gp 91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: involvement of the reninangiotensin system. Hypertens Res 29: 813-820, 2006.
    • (2006) Hypertens Res , vol.29 , pp. 813-820
    • Akasaki, T.1    Ohya, Y.2    Kuroda, J.3    Eto, K.4    Abe, I.5    Sumimoto, H.6    Lida, M.7
  • 8
    • 0036667283 scopus 로고    scopus 로고
    • The mechanism(s) of hypoxic pulmonary vasoconstriction: Potassium channels, redox O2 sensors, and controver-sies
    • Archer S, Michelakis E. The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O2 sensors, and controver-sies. News Physiol Sci 17: 131-137, 2002.
    • (2002) News Physiol Sci , vol.17 , pp. 131-137
    • Archer, S.1    Michelakis, E.2
  • 11
    • 35548967033 scopus 로고    scopus 로고
    • Comparison of H2O2-in-duced vasoconstriction in the abdominal aorta and mesenteric artery of the mouse
    • Ardanaz N, Beierwaltes WH, Pagano PJ. Comparison of H2O2-in-duced vasoconstriction in the abdominal aorta and mesenteric artery of the mouse. Vascul Pharmacol 47: 288-294, 2007.
    • (2007) Vascul Pharmacol , vol.47 , pp. 288-294
    • Ardanaz, N.1    Beierwaltes, W.H.2    Pagano, P.J.3
  • 12
    • 42549084309 scopus 로고    scopus 로고
    • Distinct hydrogen peroxide-induced constriction in multiple mouse arteries: Potential influence of vascular polarization
    • Ardanaz N, Beierwaltes WH, Pagano PJ. Distinct hydrogen peroxide-induced constriction in multiple mouse arteries: potential influence of vascular polarization. Pharmacol Rep 60: 61-67, 2008.
    • (2008) Pharmacol Rep , vol.60 , pp. 61-67
    • Ardanaz, N.1    Beierwaltes, W.H.2    Pagano, P.J.3
  • 13
    • 33644805695 scopus 로고    scopus 로고
    • Transgenic extracellular superoxide dismutase protects postnatal alveolar epithelial proliferation and development during hyperoxia
    • Auten RL, O'Reilly MA, Oury TD, Nozik-Grayck E, Whorton MH. Transgenic extracellular superoxide dismutase protects postnatal alveolar epithelial proliferation and development during hyperoxia. Am J Physiol Lung Cell Mol Physiol 290: L32-L40, 2006.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Auten, R.L.1    O'Reilly, M.A.2    Oury, T.D.3    Nozik-Grayck, E.4    Whorton, M.H.5
  • 17
    • 0035036994 scopus 로고    scopus 로고
    • Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction
    • Barman SA. Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction. An J Physiol Lung Cell Mol Physiol 280: L888-L895, 2001.
    • (2001) An J Physiol Lung Cell Mol Physiol , vol.280
    • Barman, S.A.1
  • 18
    • 0033897196 scopus 로고    scopus 로고
    • Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells
    • Bayraktutan U, Blayney L, Shah AM. Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells. Arterioscler Thromb Vasc Biol 20: 1903-1911, 2000.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1903-1911
    • Bayraktutan, U.1    Blayney, L.2    Shah, A.M.3
  • 19
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 20
    • 34547852400 scopus 로고    scopus 로고
    • NOX family NADPH oxidases: Not just in mammals
    • Bedard K, Lardy B, Krause KH. NOX family NADPH oxidases: not just in mammals. Biochimie 89: 1107-1112, 2007.
    • (2007) Biochimie , vol.89 , pp. 1107-1112
    • Bedard, K.1    Lardy, B.2    Krause, K.H.3
  • 23
    • 14044269009 scopus 로고    scopus 로고
    • The role of oxidative stress in chronic obstructive pulmonary disease
    • Bowler RP, Barnes PJ, Crapo JD. The role of oxidative stress in chronic obstructive pulmonary disease. COPD 1: 255-277, 2004.
    • (2004) COPD , vol.1 , pp. 255-277
    • Bowler, R.P.1    Barnes, P.J.2    Crapo, J.D.3
  • 24
    • 11144338749 scopus 로고    scopus 로고
    • Vascular NADPH oxidases: Molecular mech-anisms of activation
    • Brandes RP, Kreuzer J. Vascular NADPH oxidases: molecular mech-anisms of activation. Cardiovasc Res 65: 16-27, 2005.
    • (2005) Cardiovasc Res , vol.65 , pp. 16-27
    • Brandes, R.P.1    Kreuzer, J.2
  • 28
    • 0022644878 scopus 로고
    • Hydrogen peroxide induced pulmonary vasoconstriction in isolated rat lungs is attenuated by U60,257, a leucotriene synthesis blocker
    • Burghuber OC, Strife R, Zirolli J, Mathias MM, Murphy RC, Reeves JT, Voelkel NF. Hydrogen peroxide induced pulmonary vasoconstriction in isolated rat lungs is attenuated by U60,257, a leucotriene synthesis blocker. Wien Klin Wochenschr 98: 117-119, 1986.
    • (1986) Wien Klin Wochenschr , vol.98 , pp. 117-119
    • Burghuber, O.C.1    Strife, R.2    Zirolli, J.3    Mathias, M.M.4    Murphy, R.C.5    Reeves, J.T.6    Voelkel, N.F.7
  • 30
    • 0023234054 scopus 로고
    • Hydrogen peroxide elicits pulmonary arterial relaxation and guanylate cyclase activation
    • Burke TM, Wolin MS. Hydrogen peroxide elicits pulmonary arterial relaxation and guanylate cyclase activation. Am J Physiol Heart Circ Physiol 252: H721-H732, 1987.
    • (1987) Am J Physiol Heart Circ Physiol , vol.252
    • Burke, T.M.1    Wolin, M.S.2
  • 32
    • 0029026825 scopus 로고
    • Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: Protective effect of anion channel blocker
    • Chakraborti S, Batabyal SK, Chakraborti T. Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: protective effect of anion channel blocker. Mol Cell Biochem 146: 91-98. 1995.
    • (1995) Mol Cell Biochem , vol.146 , pp. 91-98
    • Chakraborti, S.1    Batabyal, S.K.2    Chakraborti, T.3
  • 33
    • 0027034432 scopus 로고
    • Role of serine esterase in hydrogen peroxide-mediated activation of phospholipase A2 in rabbit pulmonary arterial smooth muscle cells
    • Chakraborti S, Batabyal SK, Dutta G, Michael JR. Role of serine esterase in hydrogen peroxide-mediated activation of phospholipase A2 in rabbit pulmonary arterial smooth muscle cells. Indian J Biochem Biophys 29: 477-481, 1992.
    • (1992) Indian J Biochem Biophys , vol.29 , pp. 477-481
    • Chakraborti, S.1    Batabyal, S.K.2    Dutta, G.3    Michael, J.R.4
  • 35
    • 0035897653 scopus 로고    scopus 로고
    • Homologs of gp91phox: Cloning and tissue expression of Nox3, Nox4, and Nox5
    • Cheng G, Cao Z, Xu X, van Meir EG, Lambeth JD. Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. Gene 269: 131-140, 2001.
    • (2001) Gene , vol.269 , pp. 131-140
    • Cheng, G.1    Cao, Z.2    Xu, X.3    van Meir, E.G.4    Lambeth, J.D.5
  • 36
    • 23844493190 scopus 로고    scopus 로고
    • Alternative mRNA splice forms of NOXO1: Differential tissue expression and regulation of Nox1 and Nox3
    • Cheng G, Lambeth JD. Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3. Gene 356: 118-126, 2005.
    • (2005) Gene , vol.356 , pp. 118-126
    • Cheng, G.1    Lambeth, J.D.2
  • 38
    • 33947602453 scopus 로고    scopus 로고
    • Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries
    • Cogolludo A, Frazziano G, Cobeno L, Moreno L, Lodi F, Villamor E, Tamargo J, Perez-Vizcaino F. Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries. Ann NYAcad Sci 1091: 41-51, 2006.
    • (2006) Ann NYAcad Sci , vol.1091 , pp. 41-51
    • Cogolludo, A.1    Frazziano, G.2    Cobeno, L.3    Moreno, L.4    Lodi, F.5    Villamor, E.6    Tamargo, J.7    Perez-Vizcaino, F.8
  • 40
    • 13244290055 scopus 로고    scopus 로고
    • Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of in- sulinlike growth factor-1 receptor transactivation
    • Cruzado MC, Risler NR, Miatello RM, Yao G, Schiffrin EL, Touyz RM. Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of in- sulinlike growth factor-1 receptor transactivation. Am J Hypertens 18: 81-87, 2005.
    • (2005) Am J Hypertens , vol.18 , pp. 81-87
    • Cruzado, M.C.1    Risler, N.R.2    Miatello, R.M.3    Yao, G.4    Schiffrin, E.L.5    Touyz, R.M.6
  • 41
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factorbetal-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factorbetal-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 97: 900-907. 2005.
    • (2005) Circ Res , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 42
    • 0036056296 scopus 로고    scopus 로고
    • Characterization of ThOX proteins as components of the thyroid H2O2-generating system
    • De Deken X, Wang D, Dumont JE, Miot F. Characterization of ThOX proteins as components of the thyroid H2O2-generating system. Exp Cell Res 273: 187-196, 2002.
    • (2002) Exp Cell Res , vol.273 , pp. 187-196
    • de Deken, X.1    Wang, D.2    Dumont, J.E.3    Miot, F.4
  • 46
    • 74249086519 scopus 로고    scopus 로고
    • Hypoxia-induced hyperreactivity of pulmonary arteries: Role of cyclooxygenase-2, isoprostanes, and thromboxane receptors
    • Delannoy E, Courtois A, Freund-Michel V, Leblais V, Marthan R, Muller B. Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors. Cardiovasc Res 85: 582-592, 2010.
    • (2010) Cardiovasc Res , vol.85 , pp. 582-592
    • Delannoy, E.1    Courtois, A.2    Freund-Michel, V.3    Leblais, V.4    Marthan, R.5    Muller, B.6
  • 48
    • 77953518507 scopus 로고    scopus 로고
    • The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1
    • Diebold I, Petry A, Hess J, Gorlach A. The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1. Mol Biol Cell 21: 2087-2096. 2010.
    • (2010) Mol Biol Cell , vol.21 , pp. 2087-2096
    • Diebold, I.1    Petry, A.2    Hess, J.3    Gorlach, A.4
  • 50
    • 0033228518 scopus 로고    scopus 로고
    • Mechanisms of structural remodeling in chronic pulmonary hypertension
    • Durmowicz AG, Stenmark KR. Mechanisms of structural remodeling in chronic pulmonary hypertension. Pediatr Rev 20: e91-e102, 1999.
    • (1999) Pediatr Rev , vol.20
    • Durmowicz, A.G.1    Stenmark, K.R.2
  • 53
    • 2342591369 scopus 로고    scopus 로고
    • Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C
    • Erdos B, Snipes JA, Miller AW, Busija DW. Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C. Diabetes 53: 1352-1359, 2004.
    • (2004) Diabetes , vol.53 , pp. 1352-1359
    • Erdos, B.1    Snipes, J.A.2    Miller, A.W.3    Busija, D.W.4
  • 54
    • 84980110245 scopus 로고
    • Observations on the puhnonary arterial blood pressure in the cat
    • von Euler US, Liljestrand G. Observations on the puhnonary arterial blood pressure in the cat. Acta Physiol Scand 12: 301-320, 1946.
    • (1946) Acta Physiol Scand , vol.12 , pp. 301-320
    • von Euler, U.S.1    Liljestrand, G.2
  • 57
    • 57049088175 scopus 로고    scopus 로고
    • Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension
    • Fike CD, Slaughter JC, Kaplowitz MR, Zhang Y, Aschner JL. Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 295: L881-L888, 2008.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Fike, C.D.1    Slaughter, J.C.2    Kaplowitz, M.R.3    Zhang, Y.4    Aschner, J.L.5
  • 58
    • 70349354334 scopus 로고    scopus 로고
    • Mechanisms and function of DUOX in epithelia of the lung
    • Fischer H. Mechanisms and function of DUOX in epithelia of the lung. Antioxid Redox Signal 11: 2453-2465, 2009.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2453-2465
    • Fischer, H.1
  • 60
    • 0032954805 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
    • Folz RJ, Abushamaa AM, Suliman HB. Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia. J Clin Invest 103: 1055-1066, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 1055-1066
    • Folz, R.J.1    Abushamaa, A.M.2    Suliman, H.B.3
  • 61
    • 18244386946 scopus 로고    scopus 로고
    • Regulated hydrogen peroxide production by Duox in human airway epithelial cells
    • Forteza R, Salathe M, Miot F, Conner GE. Regulated hydrogen peroxide production by Duox in human airway epithelial cells. Am J Respir Cell Mol Biol 32: 462-469, 2005.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 462-469
    • Forteza, R.1    Salathe, M.2    Miot, F.3    Conner, G.E.4
  • 64
    • 0344125376 scopus 로고    scopus 로고
    • Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery
    • Gao YJ, Hirota S, Zhang DW, Janssen LJ, Lee RM. Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery. Br J Pharmacol 138: 1085-1092, 2003.
    • (2003) Br J Pharmacol , vol.138 , pp. 1085-1092
    • Gao, Y.J.1    Hirota, S.2    Zhang, D.W.3    Janssen, L.J.4    Lee, R.M.5
  • 65
    • 0038036799 scopus 로고    scopus 로고
    • Proteins homologous to p47Phox and p67Ph x support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells
    • Geiszt M, Lekstrom K, Witta J, Leto TL. Proteins homologous to p47Phox and p67Ph x support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells. J Biol Chem 278: 20006-20012, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 20006-20012
    • Geiszt, M.1    Lekstrom, K.2    Witta, J.3    Leto, T.L.4
  • 66
    • 0042203535 scopus 로고    scopus 로고
    • Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense
    • Geiszt M, Witta J, Baffi J, Lekstrom K, Leto TL. Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. FASEB J 17: 1502-1504, 2003.
    • (2003) FASEB J , vol.17 , pp. 1502-1504
    • Geiszt, M.1    Witta, J.2    Baffi, J.3    Lekstrom, K.4    Leto, T.L.5
  • 68
    • 34250842260 scopus 로고    scopus 로고
    • Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothy-roidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor
    • Grasberger H, De Deken X, Miot F, Pohlenz J, Refetoff S. Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothy-roidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor. Mol Endocrinol 21: 1408-1421, 2007.
    • (2007) Mol Endocrinol , vol.21 , pp. 1408-1421
    • Grasberger, H.1    de Deken, X.2    Miot, F.3    Pohlenz, J.4    Refetoff, S.5
  • 70
    • 1942468123 scopus 로고    scopus 로고
    • Novel NAD(P)H oxidases in the cardiovascular system
    • Griendling KK. Novel NAD(P)H oxidases in the cardiovascular system. Heart 90: 491-493, 2004.
    • (2004) Heart , vol.90 , pp. 491-493
    • Griendling, K.K.1
  • 71
    • 0034725652 scopus 로고    scopus 로고
    • Reactive oxygen species as mediators of angiotensin II signaling
    • Griendling KK, Ushio-Fukai M. Reactive oxygen species as mediators of angiotensin II signaling. Regul Pept 91: 21-27, 2000.
    • (2000) Regul Pept , vol.91 , pp. 21-27
    • Griendling, K.K.1    Ushio-Fukai, M.2
  • 74
    • 84924277503 scopus 로고    scopus 로고
    • Advanced glycosylated end products-mediated activation of polymor-phonuclear neutrophils in diabetes mellitus and associated oxidative stress
    • Gupta A, Tripathi AK, Tripathi RL, Madhu SV, Banerjee BD. Advanced glycosylated end products-mediated activation of polymor-phonuclear neutrophils in diabetes mellitus and associated oxidative stress. Indian J Biochem Biophys 44: 373-378, 2007.
    • (2007) Indian J Biochem Biophys , vol.44 , pp. 373-378
    • Gupta, A.1    Tripathi, A.K.2    Tripathi, R.L.3    Madhu, S.V.4    Banerjee, B.D.5
  • 76
    • 79960699752 scopus 로고    scopus 로고
    • Nox2-derived reactive oxygen species contribute to hypercholester-olemia-induced inhibition of neovascularization: Effects on endothelial progenitor cells and mature endothelial cells
    • Haddad P, Dussault S, Groleau J, Turgeon J, Maingrette F, Rivard A. Nox2-derived reactive oxygen species contribute to hypercholester-olemia-induced inhibition of neovascularization: effects on endothelial progenitor cells and mature endothelial cells. Atherosclerosis 217: 340-349, 2011.
    • (2011) Atherosclerosis , vol.217 , pp. 340-349
    • Haddad, P.1    Dussault, S.2    Groleau, J.3    Turgeon, J.4    Maingrette, F.5    Rivard, A.6
  • 77
    • 24044451233 scopus 로고    scopus 로고
    • Differential regulation of dual NADPH oxidases/peroxidases, Duox 1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium
    • Harper RW, Xu C, Eiserich JP, Chen Y, Kao CY, Thai P, Setiadi H, Wu R. Differential regulation of dual NADPH oxidases/peroxidases, Duox 1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Letr 579: 4911-4917, 2005.
    • (2005) FEBS Letr , vol.579 , pp. 4911-4917
    • Harper, R.W.1    Xu, C.2    Eiserich, J.P.3    Chen, Y.4    Kao, C.Y.5    Thai, P.6    Setiadi, H.7    Wu, R.8
  • 78
    • 13544251464 scopus 로고    scopus 로고
    • A reappraisal of the genomic organization of human Noxl and its splice variants
    • Harper RW, Xu C, Soucek K, Setiadi H, Eiserich JP. A reappraisal of the genomic organization of human Noxl and its splice variants. Arch Biochem Biophys 435: 323-330, 2005.
    • (2005) Arch Biochem Biophys , vol.435 , pp. 323-330
    • Harper, R.W.1    Xu, C.2    Soucek, K.3    Setiadi, H.4    Eiserich, J.P.5
  • 79
    • 34250349160 scopus 로고    scopus 로고
    • Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling
    • Hawkins BJ, Madesh M, Kirkpatrick CJ, Fisher AB. Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling. Mol Biol Cell 18: 2002-2012, 2007.
    • (2007) Mol Biol Cell , vol.18 , pp. 2002-2012
    • Hawkins, B.J.1    Madesh, M.2    Kirkpatrick, C.J.3    Fisher, A.B.4
  • 80
    • 40749090043 scopus 로고    scopus 로고
    • PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation
    • Hemnes AR, Zaiman A, Champion HC. PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation. Am J Physiol Lung Cell Mol Physiol 294: L24-L33, 2008.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Hemnes, A.R.1    Zaiman, A.2    Champion, H.C.3
  • 82
    • 64249168985 scopus 로고    scopus 로고
    • NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: The role of autocrine production of transforming growth factor-β1 and insulin-like growth factor binding protein-3
    • Ismail S, Sturrock A, Wu P, Cahill B, Norman K, Huecksteadt T, Sanders K, Kennedy T, Hoidal J. NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-β1 and insulin-like growth factor binding protein-3. Am J Physiol Lung Cell Mol Physiol 296: L489-L499, 2009.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296
    • Ismail, S.1    Sturrock, A.2    Wu, P.3    Cahill, B.4    Norman, K.5    Huecksteadt, T.6    Sanders, K.7    Kennedy, T.8    Hoidal, J.9
  • 83
    • 39149119639 scopus 로고    scopus 로고
    • Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats
    • Jankov RP, Kantores C, Pan J, Belik J. Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats. Am J Physiol Lung Cell Mol Physiol 294: L233-L245, 2008.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Jankov, R.P.1    Kantores, C.2    Pan, J.3    Belik, J.4
  • 84
    • 4544302627 scopus 로고    scopus 로고
    • Endothelium-derived reactive oxygen species and endothelin- 1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia
    • Jernigan NL, Walker BR, Resta TC. Endothelium-derived reactive oxygen species and endothelin- 1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 287: L801-L808, 2004.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287
    • Jernigan, N.L.1    Walker, B.R.2    Resta, T.C.3
  • 85
    • 33846326878 scopus 로고    scopus 로고
    • Hypoxia induces transforming growth factor-betal gene expression in the pulmonary artery of rats via hypoxia-inducible factor-1 alpha
    • Jiang Y, Dai A, Li Q, Hu R. Hypoxia induces transforming growth factor-betal gene expression in the pulmonary artery of rats via hypoxia-inducible factor-1 alpha. Acta Biochim Biophys Sin (Shanghai) 39: 73-80, 2007.
    • (2007) Acta Biochim Biophys Sin (Shanghai) , vol.39 , pp. 73-80
    • Jiang, Y.1    Dai, A.2    Li, Q.3    Hu, R.4
  • 86
    • 0030820714 scopus 로고    scopus 로고
    • Activation of tyrosine kinases in H2O2-induced contraction in pulmonary artery
    • Jin N, Rhoades RA. Activation of tyrosine kinases in H2O2-induced contraction in pulmonary artery. Am J Physiol Heart Circ Physiol 272: H2686-H2692, 1997.
    • (1997) Am J Physiol Heart Circ Physiol , vol.272
    • Jin, N.1    Rhoades, R.A.2
  • 87
    • 0034522682 scopus 로고    scopus 로고
    • Hydrogen peroxide-an intracellular signal in the pulmonary circulation: Involvement in hypoxic pulmonary vasoconstriction
    • Jones RD, Morice AH. Hydrogen peroxide-an intracellular signal in the pulmonary circulation: involvement in hypoxic pulmonary vasoconstriction. Pharmacol Ther 88: 153-161, 2000.
    • (2000) Pharmacol Ther , vol.88 , pp. 153-161
    • Jones, R.D.1    Morice, A.H.2
  • 88
    • 0027241747 scopus 로고
    • Activities of superoxide dismutases and NADPH oxidase in neutrophils obtained from asthmatic and normal donors
    • Joseph BZ, Routes JM, Borish L. Activities of superoxide dismutases and NADPH oxidase in neutrophils obtained from asthmatic and normal donors. Inflammation 17: 361-370, 1993.
    • (1993) Inflammation , vol.17 , pp. 361-370
    • Joseph, B.Z.1    Routes, J.M.2    Borish, L.3
  • 91
    • 24744468043 scopus 로고    scopus 로고
    • Point mutations in the proline-rich region of p22 phox are dominant inhibitors of Noxl- and Nox2-dependent reactive oxygen generation
    • Kawahara T, Ritsick D, Cheng G, Lambeth JD. Point mutations in the proline-rich region of p22 phox are dominant inhibitors of Noxl- and Nox2-dependent reactive oxygen generation. J Biol Chem 280: 31859-31869. 2005.
    • (2005) J Biol Chem , vol.280 , pp. 31859-31869
    • Kawahara, T.1    Ritsick, D.2    Cheng, G.3    Lambeth, J.D.4
  • 93
    • 33845430467 scopus 로고    scopus 로고
    • Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade
    • Koff JL, Shao MX, Kim S, Ueki IF, Nadel JA. Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade. J Immunol 177: 8693-8700, 2006.
    • (2006) J Immunol , vol.177 , pp. 8693-8700
    • Koff, J.L.1    Shao, M.X.2    Kim, S.3    Ueki, I.F.4    Nadel, J.A.5
  • 94
    • 34147118950 scopus 로고    scopus 로고
    • Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension
    • Konduri GG, Bakhutashvili I, Eis A, Pritchard K Jr. Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension. Am J Physiol Heart Circ Physiol 292: H1812-H1820, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Konduri, G.G.1    Bakhutashvili, I.2    Eis, A.3    Pritchard Jr., K.4
  • 95
    • 54449083292 scopus 로고    scopus 로고
    • Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: Modulation by nitric oxide
    • Korge P, Ping P, Weiss JN. Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide. Circ Res 103: 873-880, 2008.
    • (2008) Circ Res , vol.103 , pp. 873-880
    • Korge, P.1    Ping, P.2    Weiss, J.N.3
  • 96
    • 0033695425 scopus 로고    scopus 로고
    • Plasma hydrogen peroxide production in human essential hypertension: Role of heredity, gender, and ethnicity
    • Lacy F, Kailasam MT, O'Connor DT, Schmid-Schönbein GW, Par-mer RJ. Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity. Hypertension 36: 878-884, 2000.
    • (2000) Hypertension , vol.36 , pp. 878-884
    • Lacy, F.1    Kailasam, M.T.2    O'Connor, D.T.3    Schmid-Schönbein, G.W.4    Par-Mer, R.J.5
  • 97
    • 34250888056 scopus 로고    scopus 로고
    • Regulation of Nox and Duox enzymatic activity and expression
    • Lambeth JD, Kawahara T, Diebold B. Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med 43: 319-331, 2007.
    • (2007) Free Radic Biol Med , vol.43 , pp. 319-331
    • Lambeth, J.D.1    Kawahara, T.2    Diebold, B.3
  • 98
    • 15444379857 scopus 로고    scopus 로고
    • Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia
    • Lavigne MC, Eppihimer MJ. Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia. Biochem Biophys Res Commun 330: 194-203, 2005.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 194-203
    • Lavigne, M.C.1    Eppihimer, M.J.2
  • 99
    • 49749100079 scopus 로고    scopus 로고
    • NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts
    • Li S, Tabar SS, Malec V, Eul BG, Klepetko W, Weissmann N, Grimminger F, Seeger W, Rose F, Hanze J. NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts. Antioxid Redox Signal 10: 1687-1698, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1687-1698
    • Li, S.1    Tabar, S.S.2    Malec, V.3    Eul, B.G.4    Klepetko, W.5    Weissmann, N.6    Grimminger, F.7    Seeger, W.8    Rose, F.9    Hanze, J.10
  • 101
    • 0038369971 scopus 로고    scopus 로고
    • NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy
    • Liu J, Yang F, Yang XP, Jankowski M, Pagano PJ. NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy. Arterioscler Thromb Vasc Biol 23: 776-782, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 776-782
    • Liu, J.1    Yang, F.2    Yang, X.P.3    Jankowski, M.4    Pagano, P.J.5
  • 104
    • 4644248958 scopus 로고    scopus 로고
    • Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin
    • Liu Y, Suzuki YJ, Day RM, Fanburg BL. Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. Circ Res 95: 579-586, 2004.
    • (2004) Circ Res , vol.95 , pp. 579-586
    • Liu, Y.1    Suzuki, Y.J.2    Day, R.M.3    Fanburg, B.L.4
  • 105
    • 18844397807 scopus 로고    scopus 로고
    • Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries
    • Lucchesi PA, Behnadani S, Matrougui K. Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries. J Hypertens 23: 571-579, 2005.
    • (2005) J Hypertens , vol.23 , pp. 571-579
    • Lucchesi, P.A.1    Behnadani, S.2    Matrougui, K.3
  • 106
    • 39449091629 scopus 로고    scopus 로고
    • Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer
    • Luxen S, Belinsky SA, Knaus UG. Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Res 68: 1037-1045, 2008.
    • (2008) Cancer Res , vol.68 , pp. 1037-1045
    • Luxen, S.1    Belinsky, S.A.2    Knaus, U.G.3
  • 108
    • 79957935756 scopus 로고    scopus 로고
    • NADPH oxidase-derived reactive oxygen species: Involve-ment in vascular physiology and pathology
    • Manea A. NADPH oxidase-derived reactive oxygen species: involve-ment in vascular physiology and pathology. Cell Tissue Res 342: 325- 339, 2010.
    • (2010) Cell Tissue Res , vol.342 , pp. 325
    • Manea, A.1
  • 110
    • 27144444002 scopus 로고    scopus 로고
    • Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma
    • Maranchie JK, Zhan Y. Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. Cancer Res 65: 9190-9193, 2005.
    • (2005) Cancer Res , vol.65 , pp. 9190-9193
    • Maranchie, J.K.1    Zhan, Y.2
  • 113
    • 45949087149 scopus 로고    scopus 로고
    • Generation of oxidants by hypoxic human pulmonary and coronary smooth-muscle cells
    • Mehta JP, Campian JL, Guardiola J, Cabrera JA, Weir EK, Eaton JW. Generation of oxidants by hypoxic human pulmonary and coronary smooth-muscle cells. Chest 133: 1410-1414, 2008.
    • (2008) Chest , vol.133 , pp. 1410-1414
    • Mehta, J.P.1    Campian, J.L.2    Guardiola, J.3    Cabrera, J.A.4    Weir, E.K.5    Eaton, J.W.6
  • 120
    • 0028233138 scopus 로고
    • NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium
    • Mohazzab KM, Kaminski PM, Wolin MS. NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium. Am J Physiol Heart Circ Physiol 266: H2568-H2572, 1994.
    • (1994) Am J Physiol Heart Circ Physiol , vol.266
    • Mohazzab, K.M.1    Kaminski, P.M.2    Wolin, M.S.3
  • 121
    • 0028596392 scopus 로고
    • Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle
    • Mohazzab KM, Wolin MS. Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle. Am J Physiol Lung Cell Mol Physiol 267: L815-L822, 1994.
    • (1994) Am J Physiol Lung Cell Mol Physiol , vol.267
    • Mohazzab, K.M.1    Wolin, M.S.2
  • 122
    • 0028829577 scopus 로고
    • Potential role of NADH oxidoreductase-derived reactive O2 species in calf pul-monary arterial Po2-elicited responses
    • Mohazzab KM, Fayngersh RP, Kaminski PM, Wolin MS. Potential role of NADH oxidoreductase-derived reactive O2 species in calf pul-monary arterial Po2-elicited responses. Am J Physiol Lung Cell Mol Physiol 269: L637-L644, 1995.
    • (1995) Am J Physiol Lung Cell Mol Physiol , vol.269
    • Mohazzab, K.M.1    Fayngersh, R.P.2    Kaminski, P.M.3    Wolin, M.S.4
  • 123
    • 0028596392 scopus 로고
    • Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle
    • Mohazzab KM, Wolin MS. Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle. Am J Physiol Lung Cell Mol Physiol 267: L815-L822, 1994.
    • (1994) Am J Physiol Lung Cell Mol Physiol , vol.267
    • Mohazzab, K.M.1    Wolin, M.S.2
  • 125
    • 14944377713 scopus 로고    scopus 로고
    • Increased oxidative stress in acute exacerbations of asthma
    • Nadeem A, Raj HG, Chhabra SK. Increased oxidative stress in acute exacerbations of asthma. J Asthma 42: 45-50, 2005.
    • (2005) J Asthma , vol.42 , pp. 45-50
    • Nadeem, A.1    Raj, H.G.2    Chhabra, S.K.3
  • 126
    • 0030824455 scopus 로고    scopus 로고
    • Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells
    • Narayanan PK, Goodwin EH, Lehnert BE. Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res 57: 3963-3971. 1997.
    • (1997) Cancer Res , vol.57 , pp. 3963-3971
    • Narayanan, P.K.1    Goodwin, E.H.2    Lehnert, B.E.3
  • 127
    • 0030006853 scopus 로고    scopus 로고
    • Role of cytokines, tyrosine kinase, and protein kinase C on production of super-oxide and induction of scavenging enzymes in human leukocytes
    • Niwa Y, Ozaki Y, Kanoh T, Akamatsu H, Kurisaka M. Role of cytokines, tyrosine kinase, and protein kinase C on production of super-oxide and induction of scavenging enzymes in human leukocytes. Clin Immunol Immunopathol 79: 303-313, 1996.
    • (1996) Clin Immunol Immunopathol , vol.79 , pp. 303-313
    • Niwa, Y.1    Ozaki, Y.2    Kanoh, T.3    Akamatsu, H.4    Kurisaka, M.5
  • 129
    • 0031686132 scopus 로고    scopus 로고
    • Ciga-rette smoking does not increase hydrogen peroxide levels in expired breath condensate of patients with stable COPD
    • Nowak D, Kasielski M, Pietras T, Bialasiewicz P, Antczak A. Ciga-rette smoking does not increase hydrogen peroxide levels in expired breath condensate of patients with stable COPD. Monaldi Arch Chest Dis 53: 268-273, 1998.
    • (1998) Monaldi Arch Chest Dis , vol.53 , pp. 268-273
    • Nowak, D.1    Kasielski, M.2    Pietras, T.3    Bialasiewicz, P.4    Antczak, A.5
  • 133
    • 0344688403 scopus 로고    scopus 로고
    • Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature
    • Paddenberg R, Goldenberg A, Faulhammer P, Braun-Dullaeus RC, Kummer W. Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature. Adv Exp Med Biol 536: 163-169, 2003.
    • (2003) Adv Exp Med Biol , vol.536 , pp. 163-169
    • Paddenberg, R.1    Goldenberg, A.2    Faulhammer, P.3    Braun-Dullaeus, R.C.4    Kummer, W.5
  • 134
    • 4744360664 scopus 로고    scopus 로고
    • NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells
    • Papaiahgari S, Kleeberger SR, Cho HY, Kalvakolanu DV, Reddy SP. NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells. J Biol Chem 279: 42302-42312, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 42302-42312
    • Papaiahgari, S.1    Kleeberger, S.R.2    Cho, H.Y.3    Kalvakolanu, D.V.4    Reddy, S.P.5
  • 138
    • 60749126367 scopus 로고    scopus 로고
    • Regulation of NADPH oxidase in vascular endothelium: The role of phospholipases, protein kinases, and cytoskeletal proteins
    • Pendyala S, Usatyuk PV, Gorshkova IA, Garcia JG, Natarajan V. Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins. Antioxid Re-dox Signal 11: 841-860, 2009.
    • (2009) Antioxid Re-dox Signal , vol.11 , pp. 841-860
    • Pendyala, S.1    Usatyuk, P.V.2    Gorshkova, I.A.3    Garcia, J.G.4    Natarajan, V.5
  • 140
    • 0035581336 scopus 로고    scopus 로고
    • Effect of apocynin on ozoneinduced airway hyperresponsiveness to methacholine in asthmatics
    • Peters EA, Hiltermann JT, Stolk J. Effect of apocynin on ozoneinduced airway hyperresponsiveness to methacholine in asthmatics. Free Radic Biol Med 31: 1442-1447, 2001.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1442-1447
    • Peters, E.A.1    Hiltermann, J.T.2    Stolk, J.3
  • 147
    • 46749142123 scopus 로고    scopus 로고
    • Molecular pathogenesis of pulmonary arterial hypertension
    • Rabinovitch M. Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest 118: 2372-2379. 2008.
    • (2008) J Clin Invest , vol.118 , pp. 2372-2379
    • Rabinovitch, M.1
  • 150
    • 0025097230 scopus 로고
    • Signal transduction in hypoxic pulmonary vasoconstriction (HPV)
    • Rhoades RA, Jin N, Packer CS. Signal transduction in hypoxic pulmonary vasoconstriction (HPV). Prog Clin Biol Res 327: 565-573, 1990.
    • (1990) Prog Clin Biol Res , vol.327 , pp. 565-573
    • Rhoades, R.A.1    Jin, N.2    Packer, C.S.3
  • 151
    • 65449180375 scopus 로고    scopus 로고
    • Activation of dual oxidases Duoxl and Duox2: Differential regulation mediated by campdependent protein kinase and protein kinase C-dependent phosphorylation
    • Rigutto S, Hoste C, Grasberger H, Milenkovic M, Communi D, Dumont JE, Corvilain B, Miot F, De Deken X. Activation of dual oxidases Duoxl and Duox2: differential regulation mediated by campdependent protein kinase and protein kinase C-dependent phosphorylation. J Biol Chem 284: 6725-6734, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 6725-6734
    • Rigutto, S.1    Hoste, C.2    Grasberger, H.3    Milenkovic, M.4    Communi, D.5    Dumont, J.E.6    Corvilain, B.7    Miot, F.8    de Deken, X.9
  • 154
    • 4344710449 scopus 로고    scopus 로고
    • NADPH oxidasedependent acid production in airway epithelial cells
    • Schwarzer C, Machen TE, Illek B, Fischer H. NADPH oxidasedependent acid production in airway epithelial cells. J Biol Chem 279: 36454-36461, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 36454-36461
    • Schwarzer, C.1    Machen, T.E.2    Illek, B.3    Fischer, H.4
  • 155
    • 0025279185 scopus 로고
    • Superoxide generation by hypodense eosinophils from patients with asthma
    • Sedgwick JB, Geiger KM, Busse WW. Superoxide generation by hypodense eosinophils from patients with asthma. Am Rev Respir Dis 142: 120-125, 1990.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 120-125
    • Sedgwick, J.B.1    Geiger, K.M.2    Busse, W.W.3
  • 156
    • 0022617520 scopus 로고
    • The glutathione redox cycle as a defense system against hydrogen-peroxide-induced prostanoid formation and vasoconstriction in rabbit lungs
    • Seeger W, Suttorp N, Schmidt F, Neuhof H. The glutathione redox cycle as a defense system against hydrogen-peroxide-induced prostanoid formation and vasoconstriction in rabbit lungs. Am Rev Respir Dis 133: 1029-1036, 1986.
    • (1986) Am Rev Respir Dis , vol.133 , pp. 1029-1036
    • Seeger, W.1    Suttorp, N.2    Schmidt, F.3    Neuhof, H.4
  • 157
    • 14144251241 scopus 로고    scopus 로고
    • Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells
    • Shao MX, Nadel JA. Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells. Proc Natl Acad Sci USA 102: 767-772. 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 767-772
    • Shao, M.X.1    Nadel, J.A.2
  • 160
    • 0742270734 scopus 로고    scopus 로고
    • Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts
    • Short M, Nemenoff RA, Zawada WM, Stenmark KR, Das M. Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts. Am J Physiol Cell Physiol 286: C416-C425, 2004.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Short, M.1    Nemenoff, R.A.2    Zawada, W.M.3    Stenmark, K.R.4    Das, M.5
  • 161
    • 79958128614 scopus 로고    scopus 로고
    • Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease
    • Stasch JP, Pacher P, Evgenov OV. Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease. Circulation 123: 2263-2273, 2011.
    • (2011) Circulation , vol.123 , pp. 2263-2273
    • Stasch, J.P.1    Pacher, P.2    Evgenov, O.V.3
  • 162
    • 0030934358 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling
    • Stenmark KR, Mecham RP. Cellular and molecular mechanisms of pulmonary vascular remodeling. Annu Rev Physiol 59: 89-144, 1997.
    • (1997) Annu Rev Physiol , vol.59 , pp. 89-144
    • Stenmark, K.R.1    Mecham, R.P.2
  • 163
    • 0028473441 scopus 로고
    • Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol
    • Stolk J, Hiltermann TJN, Dijkman JH, Verhoeven AJ. Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. Am J Respir Cell Mol Biol 11: 95-102, 1994.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 95-102
    • Stolk, J.1    Hiltermann, T.J.N.2    Dijkman, J.H.3    Verhoeven, A.J.4
  • 165
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
    • Szabo C, Ischiropoulos H, Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 6: 662-680. 2007.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 662-680
    • Szabo, C.1    Ischiropoulos, H.2    Radi, R.3
  • 166
    • 77950332094 scopus 로고    scopus 로고
    • Racl-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium
    • Takemura Y, Goodson P, Bao HF, Jain L, Helms MN. Racl-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium. Am J Physiol Lung Cell Mol Physiol 298: L509-L520, 2010.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298
    • Takemura, Y.1    Goodson, P.2    Bao, H.F.3    Jain, L.4    Helms, M.N.5
  • 168
    • 0029417335 scopus 로고
    • Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1
    • Thannickal VJ, Fanburg BL. Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1. J Biol Chem 270: 30334-30338, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 30334-30338
    • Thannickal, V.J.1    Fanburg, B.L.2
  • 169
    • 33845635605 scopus 로고    scopus 로고
    • Subcellular localization and function of alternatively spliced Noxol isoforms
    • Ueyama T, Lekstrom K, Tsujibe S, Saito N, Leto TL. Subcellular localization and function of alternatively spliced Noxol isoforms. Free Radic Biol Med 42: 180-190, 2007.
    • (2007) Free Radic Biol Med , vol.42 , pp. 180-190
    • Ueyama, T.1    Lekstrom, K.2    Tsujibe, S.3    Saito, N.4    Leto, T.L.5
  • 170
    • 33745217132 scopus 로고    scopus 로고
    • Redox signaling in angiogenesis: Role of NADPH oxidase
    • Ushio-Fukai M. Redox signaling in angiogenesis: role of NADPH oxidase. Cardiovasc Res 71: 226-235, 2006.
    • (2006) Cardiovasc Res , vol.71 , pp. 226-235
    • Ushio-Fukai, M.1
  • 172
    • 14544290505 scopus 로고    scopus 로고
    • Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells
    • Vejrazka M, Micek R, Stipek S. Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells. Biochim Biophys Acta 1722: 143-147, 2005.
    • (2005) Biochim Biophys Acta , vol.1722 , pp. 143-147
    • Vejrazka, M.1    Micek, R.2    Stipek, S.3
  • 173
    • 18144371956 scopus 로고    scopus 로고
    • Hydrogen peroxide is a diffusable paracrine signal for the induction of epithelial cell death by activated myofibroblasts
    • Waghray M, Cui Z, Horowitz JC, Subramanian IM, Martinez FJ, Toews GB, Thannickal VJ. Hydrogen peroxide is a diffusable paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J 19: 854-856, 2005.
    • (2005) FASEB J , vol.19 , pp. 854-856
    • Waghray, M.1    Cui, Z.2    Horowitz, J.C.3    Subramanian, I.M.4    Martinez, F.J.5    Toews, G.B.6    Thannickal, V.J.7
  • 175
    • 0028152444 scopus 로고
    • Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs
    • Wang W, Suzuki Y, Tanigaki T, Rank DR, Raffin TA. Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs. Am J Respir Crit Care Med 150: 1449-1452, 1994.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 1449-1452
    • Wang, W.1    Suzuki, Y.2    Tanigaki, T.3    Rank, D.R.4    Raffin, T.A.5
  • 176
    • 66049112085 scopus 로고    scopus 로고
    • Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: New findings for an old problem
    • Ward JP, McMurtry IF. Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem. Curr Opin Pharnacol 9: 287-296, 2009.
    • (2009) Curr Opin Pharnacol , vol.9 , pp. 287-296
    • Ward, J.P.1    McMurtry, I.F.2
  • 177
    • 0035933388 scopus 로고    scopus 로고
    • Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing
    • Waypa GB, Chandel NS, Schumacker PT. Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. Circ Res 88: 1259-1266, 2001.
    • (2001) Circ Res , vol.88 , pp. 1259-1266
    • Waypa, G.B.1    Chandel, N.S.2    Schumacker, P.T.3
  • 178
    • 33750449016 scopus 로고    scopus 로고
    • Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells
    • Waypa GB, Guzy R, Mungai PT, Mack MM, Marks JD, Roe MW, Schumacker PT. Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circ Res 99: 970-978, 2006.
    • (2006) Circ Res , vol.99 , pp. 970-978
    • Waypa, G.B.1    Guzy, R.2    Mungai, P.T.3    Mack, M.M.4    Marks, J.D.5    Roe, M.W.6    Schumacker, P.T.7
  • 180
    • 0037158626 scopus 로고    scopus 로고
    • O2 sensing in hypoxic pulmonary vasoconstriction: The mitochondrial door re-opens
    • Waypa GB, Schumacker PT. O2 sensing in hypoxic pulmonary vasoconstriction: the mitochondrial door re-opens. Respir Physiol Neurobiol 132: 81-91, 2002.
    • (2002) Respir Physiol Neurobiol , vol.132 , pp. 81-91
    • Waypa, G.B.1    Schumacker, P.T.2
  • 181
    • 0028261209 scopus 로고
    • Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells
    • Weir EK, Wyatt CN, Reeve HL, Huang J, Archer SL, Peers C. Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells. J Appl Physiol 76: 2611-2615. 1994.
    • (1994) J Appl Physiol , vol.76 , pp. 2611-2615
    • Weir, E.K.1    Wyatt, C.N.2    Reeve, H.L.3    Huang, J.4    Archer, S.L.5    Peers, C.6
  • 184
    • 34047267984 scopus 로고    scopus 로고
    • Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1
    • Wesley UV, Bove PF, Hristova M, McCarthy S, van der Vliet A. Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1. J Biol Chem 282: 3213-3220, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 3213-3220
    • Wesley, U.V.1    Bove, P.F.2    Hristova, M.3    McCarthy, S.4    van der Vliet, A.5
  • 185
    • 0028903517 scopus 로고
    • Role of ion fluxes in hydrogen peroxide pulmonary vasoconstriction
    • Wilhelm J, Herget J. Role of ion fluxes in hydrogen peroxide pulmonary vasoconstriction. Physiol Res 44: 31-37, 1995.
    • (1995) Physiol Res , vol.44 , pp. 31-37
    • Wilhelm, J.1    Herget, J.2
  • 186
    • 15544387084 scopus 로고    scopus 로고
    • Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells
    • Wojciak-Stothard B, Tsang LY, Haworth SG. Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 288: L749-L760, 2005.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Wojciak-Stothard, B.1    Tsang, L.Y.2    Haworth, S.G.3
  • 187
    • 34249101218 scopus 로고    scopus 로고
    • Cytosolic NAD(P)H regulation of redox signaling and vascular oxygen sensing
    • Wolin MS, Ahmad M, Gao Q, Gupte SA. Cytosolic NAD(P)H regulation of redox signaling and vascular oxygen sensing. Antioxid Redox Signal 9: 671-678, 2007.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 671-678
    • Wolin, M.S.1    Ahmad, M.2    Gao, Q.3    Gupte, S.A.4
  • 188
    • 77149168173 scopus 로고    scopus 로고
    • Oxidant-redox regulation of pulmonary vascular responses to hypoxia and nitric oxidecGMP signaling
    • Wolin MS, Gupte SA, Neo BH, Gao Q, Ahmad M. Oxidant-redox regulation of pulmonary vascular responses to hypoxia and nitric oxidecGMP signaling. Cardiol Rev 18: 89-93, 2010.
    • (2010) Cardiol Rev , vol.18 , pp. 89-93
    • Wolin, M.S.1    Gupte, S.A.2    Neo, B.H.3    Gao, Q.4    Ahmad, M.5
  • 193
    • 48449102079 scopus 로고    scopus 로고
    • Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F
    • Zhang L, Sheppard OR, Shah AM, Brewer AC. Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F. Free Radic Biol Med 45: 679-685, 2008.
    • (2008) Free Radic Biol Med , vol.45 , pp. 679-685
    • Zhang, L.1    Sheppard, O.R.2    Shah, A.M.3    Brewer, A.C.4
  • 194
  • 195
    • 0037369376 scopus 로고    scopus 로고
    • Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium
    • Zhang X, Shan P, Sasidhar M, Chupp GL, Flavell RA, Choi AM, Lee PJ. Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. Am J Respir Cell Mol Biol 28: 305-315, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 305-315
    • Zhang, X.1    Shan, P.2    Sasidhar, M.3    Chupp, G.L.4    Flavell, R.A.5    Choi, A.M.6    Lee, P.J.7
  • 196
    • 0031890098 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced cytoskeletal rearrangement in cultured pulmonary endothelial cells
    • Zhao Y, Davis HW. Hydrogen peroxide-induced cytoskeletal rearrangement in cultured pulmonary endothelial cells. J Cell Physiol 174: 370- 379, 1998.
    • (1998) J Cell Physiol , vol.174 , pp. 370
    • Zhao, Y.1    Davis, H.W.2


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