Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation

Journal of Biological Chemistry

Volumn 280, Issue 36, 2005, Pages 31859-31869

  Kawahara, Tsukasa ^a   Ritsick, Darren ^a,b   Cheng, Guangjie ^a   Lambeth, J David ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOLOGICAL MEMBRANES; ENZYMES; PROTEINS;

BINDING SITE; INHIBITORY EFFECT; OXIDASE; OXYGEN GENERATION;

OXYGEN;

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; NOX1 PROTEIN; NOX3 PROTEIN; NOX4 PROTEIN; NOX5 PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROLINE; PROTEIN P22; PROTEIN P22PHOX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RNA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; EMBRYO; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PHYLOGENY; POINT MUTATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SRC HOMOLOGY DOMAIN;

AMINO ACID SUBSTITUTION; CELL LINE; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; NADPH OXIDASE; PHOSPHOPROTEINS; POINT MUTATION; PROLINE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 24744468043     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501882200     Document Type: Article

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