Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

American Journal of Respiratory Cell and Molecular Biology

Volumn 28, Issue 3, 2003, Pages 305-315

  Zhang, Xuchen ^b   Shan, Peiying ^b   Sasidhar, Madhu ^b   Chupp, Geoffrey L ^b   Flavell, Richard A ^b   Choi, Augustine M K ^b   Lee, Patty J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; CYTOCHROME C; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DIPHENYLIODONIUM SALT; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; HYPEROXIA; LUNG ALVEOLUS EPITHELIUM; NICK END LABELING; NONHUMAN; RESPIRATORY FAILURE; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASES; CELL DEATH; CELL LINE, TRANSFORMED; CYSTEINE PROTEINASE INHIBITORS; ELECTRON TRANSPORT COMPLEX IV; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; FLAVONOIDS; HYPEROXIA; LUNG; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH OXIDASE; ONIUM COMPOUNDS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

ANIMALIA; MURINAE;

EID: 0037369376     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2002-0156OC     Document Type: Article

References (36)

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