Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells

Circulation Research

Volumn 99, Issue 9, 2006, Pages 970-978

  Waypa, Gregory B ^a   Guzy, Robert ^a   Mungai, Paul T ^a   Mack, Mathew M ^b   Marks, Jeremy D ^b   Roe, Michael W ^b   Schumacker, Paul T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Antioxidants; Fluorescence resonance energy transfer; Hypoxic pulmonary vasoconstriction; Reactive oxygen species; Redox signaling

Indexed keywords

ACETYLCYSTEINE; ADENOVIRUS VECTOR; ANTIOXIDANT; CALCIUM ION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MYXOTHIAZOL; PYRROLIDINEDITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CYTOSOL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYPOXIA; LUNG VASOCONSTRICTION; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; THEORETICAL MODEL;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL HYPOXIA; CYTOSOL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLUTATHIONE PEROXIDASE; MITOCHONDRIA; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATION-REDUCTION; PULMONARY ARTERY; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

EID: 33750449016     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000247068.75808.3f     Document Type: Article

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