Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis

Biochemical Pharmacology

Volumn 54, Issue 11, 1997, Pages 1205-1216

  Giri, Shri N ^a   Hyde, Dallas M ^a   Braun, Ruedi K ^a   Gaarde, William ^b   Harper, John R ^b   Pierschbacher, Michael D ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Telios Pharmaceuticals   (United States)

Author keywords

Collagen; Decorin; Fibronectin; Pulmonary fibrosis; Transforming growth factor

Indexed keywords

BLEOMYCIN; BLEOMYCIN SULFATE; DECORIN; HYDROXYPROLINE; MYELOPEROXIDASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HAMSTER; IMMUNOHISTOCHEMISTRY; INTRATRACHEAL DRUG ADMINISTRATION; LUNG FIBROSIS; LUNG LAVAGE; LUNG STRUCTURE; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BLEOMYCIN; CRICETINAE; EXTRACELLULAR MATRIX PROTEINS; HYDROXYPROLINE; IMMUNOHISTOCHEMISTRY; LUNG; MALE; MESOCRICETUS; PEROXIDASE; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEOGLYCANS; PULMONARY FIBROSIS; SUPEROXIDE DISMUTASE;

EID: 0030709198     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00343-2     Document Type: Article

References (54)

1. Clark JG, The molecular pathology of pulmonary fibrosis. In: Connective Tissue Disease (Eds. Uitto J and Pereida AJ), pp. 321-343. Marcel Decker, New York, 1987.
2. Chandler DB, Hyde DM and Giri SN, Morphometric estimates of infiltrative cellular changes during the bleomycin-induced pulmonary fibrosis in hamsters. Am J Pathol 112: 170-177, 1983.
3. Clark JG, Overton JE, Marino BA, Uitto J and Starcher BC, Collagen biosynthesis in bleomycin-induced pulmonary fibrosis in hamsters. J Lab Clin Med 96: 943-953, 1980.
4. Reiser KM, Tryka AF, Lindenschmidt RC, Last JA and Witschi JP, Changes in collagen cross-linking in bleomycin-induced pulmonary fibrosis. J Biochem Toxicol 83: 83-91, 1986.
5. Seyer JM, Hutcheson ET and Kang AH, Collagen polymorphism in idiopathic chronic pulmonary fibrosis. J Clin Invest 57: 1498-1507, 1976.
6. Crooke ST and Brander WT, Bleomycin, a review. J Med 7: 333-427, 1976.
7. Snider GL, Hayes JA and Korthy AL, Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: Pathology and stereology. Am Rev Respir Dis 117: 1099-1108, 1978.
8. Giri SN, Pharmacologic perspective in pulmonary fibrosis research. In: Focus on Pulmonary Pharmacology and Toxicology (Ed. Hollinger MA), pp. 19-55. CRC Press, Boca Raton, 1990.
9. Phan SH and Kunkel SL, Lung cytokine production in bleomycin-induced pulmonary fibrosis. Exp Lung Res 18: 29-43, 1992.
10. Khalil N, Bereznay O, Sporn M and Greenberg AH, Macrophage production of transforming growth factor β and fibroblast collagen synthesis in chronic pulmonary inflammation. J Exp Med 170: 727-737, 1989.
11. 1. Nature 346: 371-374, 1990.
12. Giri SN, Hyde DM and Hollinger MA, Effect of antibody to transforming growth factor-β on bleomycin induced accumulation of lung collagen in mice. Thorax 48: 959-966, 1993.
13. Hildebrand AM, Romaris M, Rasmussen LM, Heinegård D, Twardzik DR, Border WA and Ruoslahti E, Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor β. Biochem J 302: 527-534, 1994.
14. Yamaguchi Y, Mann DM and Ruoslahti E, Negative regulation of transforming growth factor-β by the proteoglycan decorin. Nature 346: 281-284, 1990.
15. Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD and Ruoslahti E, Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease. Nature 360: 361-364, 1992.
16. Woessner JF Jr, The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 93: 440-447, 1961.
17. Giri SN, Misra HP, Chandler DB and Chen Z, Increases in lung prolyl hydroxylase and superoxide dismutase activities during bleomycin-induced lung fibrosis in hamsters. Exp Mol Pathol 39: 317-326, 1983.
18. Hutton JJ, Tappel AL and Udenfriend S, A rapid assay for collagen proline hydroxylase. Anal Biochem 16: 384-394, 1966.
19. Goldblum SE, Wu K-M and Jay M, Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol 59: 1978-1985, 1985.
20. Hyanam DR, Hyde DM, Combs AB and Giri SN, Reduction of bleomycin-induced sequestration of neutrophils and vascular injury in hamster lungs by nitroglycerine. Inflammopharmacology 1: 249-261, 1992.
21. Ohkawa H, Ohismi N and Yagi K, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358, 1979.
22. Misra HP and Fridovich I, The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247: 3170-3175, 1972.
23. Giri SN, Hollinger MA and Schiedt MJ, The effects of paraquat and superoxide dismutase on pulmonary vascular permeability and edema in mice. Arch Environ Health 36: 149-154, 1981.
24. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ, Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
25. Bolender RP, Hyde DM and DeHoff RT, Lung morphometry: A new generation of tools and experiments for organ, tissue, cell and molecular biology. Am J Physiol 265: L521-L548, 1993.
26. Kuhn C III, Boldt J, King TE Jr, Crouch E, Vartio T and McDonald JA, An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis 140: 1693-1703, 1989.
27. Karlinski JB and Goldstein CH, Fibrotic lung diseases: A perspective. J Lab Clin Med 96: 939-942, 1980.
28. Giri SN, Hyde DM and Nakashima JM, Analysis of bronchoalveolar lavage fluid from bleomycin-induced pulmonary fibrosis in hamsters. Toxicol Pathol 14: 149-157, 1986.
29. Wang Q, Giri SN, Hyde DM and Li C, Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. Biochem Pharmacol 42: 1115-1122, 1991.
30. Harrison NK and Laurent GJ, Lung collagen metabolism: The link between inflammation and pulmonary fibrosis. In: Interstitial Pulmonary Diseases (Eds. Lama M and Borris R), pp. 47-75. CRC Press, Boca Raton, 1991.
31. Giri SN, Chen ZL, Younker WR and Schiedt MJ, Effects of intratracheal administration of bleomycin on GSH-shuttle enzymes, catalase, lipid peroxidation and collagen content in the lungs of hamsters. Toxicol Appl Pharmacol 71: 132-141, 1983.
32. Kinkade JM, Pember SO, Barnes KC, Shapiro R, Spitznagel JK and Martin LE, Differential distribution of distinct forms of myeloperoxidase in different azurophilic granule subpopulations from human neutrophils. Biochem Biophys Res Commun 114: 296-303, 1983.
33. Weiss SK, Tissue destruction by neutrophils. N Engl J Med 320: 365-376, 1989.
34. Klebanoff SJ, Phagocytic cells: Production of oxygen metabolism. In: Inflammation: Basic Principles and Clinical Correlates (Eds. Gallin JI and Goldstein IM), pp. 391-444. Raven Press, New York, 1988.
35. Dallegri F, Goretti R, Ballestrero A, Ottonello L and Patrone F, Neutrophil-induced depletion of adenosine triphosphate in target cells: Evidence for a hypochlorous acid-mediated process. J Lab Clin Med 112: 765-772, 1988.
36. 1, a potent chemoattractant for human neutrophils, bypasses classical signal-transduction pathways. Proc Natl Acad Sci USA 88: 6805-6809, 1991.
37. Fukuda Y, Ishizaki M, Masuda Y, Kimura G, Kawanami O and Masugi Y, The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage. Am J Pathol 126: 171-182, 1987.
38. 1 in developing bleomycin-induced pulmonary fibrosis in rats. J Clin Invest 92: 632-637, 1993.
39. Kahari V-M, Larjava H and Uitto J, Differential regulation of extracellular matrix proteoglycan (PG) gene expression. J Biol Chem 266: 10608-10615, 1991.
40. Hoyt DG and Lazo JS, Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-β precede bleomycin-induced pulmonary fibrosis in mice. J Pharmacol Exp Ther 246: 765-771, 1988.
41. Raghow R, Irish P and Kang AH, Coordinate regulation of transforming growth factor-β gene expression and cell proliferation in hamster lungs undergoing bleomycin-induced pulmonary fibrosis. J Clin Invest 84: 1836-1842, 1989.
42. Raghu G, Masta S, Meyers D and Narayanan AS, Collagen synthesis by normal and fibrotic human lung fibroblasts and the effect of transforming growth factor-β. Am Rev Respir Dis 140: 95-100, 1989.
43. Sporn MB, Roberts AB, Wakefield LM and Assoian RK, Transforming growth factor-β: Biological function and chemical structure. Science 233: 532-534, 1986.
44. Ignotz RA and Massagué J, Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 261: 4337-4345, 1986.
45. 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci USA 88: 6642-6646, 1991.
46. Cromack DT, Sporn MB, Roberts AM, Merino MJ, Dart LL and Norton JA, Transforming growth factor β levels in rat wound chambers. J Surg Res 42: 622-628, 1987.
47. Mustoe TA, Pierce GF, Thomason A, Gramates P, Sporn MB and Deuel TF, Accelerated healing of incisional wounds in rats induced by transforming growth factor-β. Science 237: 1333-1336, 1987.
48. Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH and Fauci AS. Transforming growth factor type β: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83: 4167-4171, 1986.
49. Varga J, Rosenbloom J and Jimenez SA, Transforming growth factor-β (TGF-β) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochem J 247: 597-604, 1987.
50. Watts CL and Fanaroff AA, Fibronectin: Role in respiratory distress syndrome and bronchopulmonary dysplasia. Semin Perinatol 16: 162-169, 1992.
51. Hernnas J, Nettelbladt O, Bjermer L, Sarnstrand B, Malmstrom A and Hallgren R, Alveolar accumulation of fibronectin and hyaluronan precedes bleomycin-induced pulmonary fibrosis in the rat. Eur Respir J 5: 404-410, 1992.
52. Reiser KM and Last JA, Pulmonary fibrosis in experimental acute respiratory disease. Am Rev Respir Dis 123: 58-63, 1981.
53. Hardingham TE and Fosang AJ, Proteoglycans: Many forms and many functions. FASEB J 6: 861-870, 1992.
54. Border WA and Noble NA, Targeting TGF-β for treatment of disease. Nat Med 1: 1000-1001, 1995.