Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Merolla, Francesco ^a,b   Luise, Chiara ^a,b   Muller, Mark T ^c   Pacelli, Roberto ^b   Fusco, Alfredo ^a,b   Celetti, Angela ^a  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2AX; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 4C; PROTEIN PH2AX; UNCLASSIFIED DRUG; CCDC6 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN PHOSPHATASE 4;

ARTICLE; CARCINOGENESIS; CATALYSIS; CCDC6 GENE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL LOSS; CELL MATURATION; CELL TRANSPORT; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE; GENE FUNCTION; GENE FUSION; GENE INACTIVATION; GENE INTERACTION; GENE LOSS; GENETIC CONSERVATION; GENOMIC INSTABILITY; GENOTOXICITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MITOSIS; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; CELL LINE; GENE SILENCING; GENETICS; HELA CELL; METABOLISM; NEOPLASM; PHOSPHORYLATION;

CELL LINE; CYTOSKELETAL PROTEINS; DNA DAMAGE; G2 PHASE; GENE SILENCING; HELA CELLS; HISTONES; HUMANS; MITOSIS; NEOPLASMS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION;

EID: 84861399281     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036177     Document Type: Article

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