-
1
-
-
12944297732
-
Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity
-
Bano D, Young KW, Guerin CJ, Lefeuvre R, Rothwell NJ, Naldini L, Rizzuto R, Carafoli E, Nicotera P. 2005. Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell 120:275-285.
-
(2005)
Cell
, vol.120
, pp. 275-285
-
-
Bano, D.1
Young, K.W.2
Guerin, C.J.3
Lefeuvre, R.4
Rothwell, N.J.5
Naldini, L.6
Rizzuto, R.7
Carafoli, E.8
Nicotera, P.9
-
2
-
-
0035283161
-
Homologues of the uncoupling protein from brown adipose tissue (UCP1): UCP2, UCP3, BMCP1 and UCP4
-
Bouillaud F, Couplan E, Pecqueur C, Ricquier D. 2001. Homologues of the uncoupling protein from brown adipose tissue (UCP1): UCP2, UCP3, BMCP1 and UCP4. Biochim Biophys Acta 1504:107-119.
-
(2001)
Biochim Biophys Acta
, vol.1504
, pp. 107-119
-
-
Bouillaud, F.1
Couplan, E.2
Pecqueur, C.3
Ricquier, D.4
-
3
-
-
4043147798
-
Mitochondrial superoxide: Production, biological effects, and activation of uncoupling proteins
-
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL, Parker N. 2004. Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radic Biol Med 37:755-767.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 755-767
-
-
Brand, M.D.1
Affourtit, C.2
Esteves, T.C.3
Green, K.4
Lambert, A.J.5
Miwa, S.6
Pakay, J.L.7
Parker, N.8
-
4
-
-
0029827804
-
Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells
-
Budd SL, Nicholls DG. 1996. Mitochondrial calcium regulation and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67:2282-2291.
-
(1996)
J Neurochem
, vol.67
, pp. 2282-2291
-
-
Budd, S.L.1
Nicholls, D.G.2
-
5
-
-
2542455473
-
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators
-
Dooley CM, Dore TM, Hanson GT, Jackson WC, Remington SJ, Tsien RY. 2004. Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. J Biol Chem 279:22284-22293.
-
(2004)
J Biol Chem
, vol.279
, pp. 22284-22293
-
-
Dooley, C.M.1
Dore, T.M.2
Hanson, G.T.3
Jackson, W.C.4
Remington, S.J.5
Tsien, R.Y.6
-
6
-
-
0028882764
-
Mitochondrial production of reactive oxygen species in cortical neurons following exposure to NMDA
-
Dugan LL, Sensi SL, Canzoniero LMT, Handran SD, Rothman SM, Lin TS, Goldberg MP, Choi DW. 1995. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to NMDA. J Neurosci 15:6377-6388.
-
(1995)
J Neurosci
, vol.15
, pp. 6377-6388
-
-
Dugan, L.L.1
Sensi, S.L.2
Canzoniero, L.M.T.3
Handran, S.D.4
Rothman, S.M.5
Lin, T.S.6
Goldberg, M.P.7
Choi, D.W.8
-
7
-
-
0017817970
-
Brown adipose tissue mitochondria: Photoaffinity labeling of the regulatory site for energy dissipation
-
Heaton GM, Wagenvoord RJ, Kemp A, Nicholls DG. 1978. Brown adipose tissue mitochondria: photoaffinity labeling of the regulatory site for energy dissipation. Eur J Biochem 82:515-521.
-
(1978)
Eur J Biochem
, vol.82
, pp. 515-521
-
-
Heaton, G.M.1
Wagenvoord, R.J.2
Kemp, A.3
Nicholls, D.G.4
-
8
-
-
0024953850
-
Neurotoxicity at the N-methyl-D-aspartate receptor in energy-compromised neurons. An hypothesis for cell death in aging and disease
-
Henneberry RC, Novelli A, Cox JA, Lysko PG. 1989. Neurotoxicity at the N-methyl-D-aspartate receptor in energy-compromised neurons. An hypothesis for cell death in aging and disease. Ann NY Acad Sci 568:225-233.
-
(1989)
Ann NY Acad Sci
, vol.568
, pp. 225-233
-
-
Henneberry, R.C.1
Novelli, A.2
Cox, J.A.3
Lysko, P.G.4
-
9
-
-
3543030406
-
In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
-
Jekabsons MB, Nicholls DG. 2004. In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem 279:32989-33000.
-
(2004)
J Biol Chem
, vol.279
, pp. 32989-33000
-
-
Jekabsons, M.B.1
Nicholls, D.G.2
-
10
-
-
33747149006
-
Bioenergetic analysis of cerebellar granule neurons undergoing apoptosis by potassium/serum deprivation
-
Jekabsons MB, Nicholls DG. 2006. Bioenergetic analysis of cerebellar granule neurons undergoing apoptosis by potassium/serum deprivation. Cell Death Differ 13:1595-1610.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1595-1610
-
-
Jekabsons, M.B.1
Nicholls, D.G.2
-
11
-
-
35848970152
-
ATP synthesis capacity, rather than reactive oxygen species, determines the susceptibility of cultured cerebellar granule neurons to glutamate excitotoxicity following 'mild uncoupling'
-
in press
-
Johnson-Cadwell LI, Jekabsons MB, Wang A, Polster BM, Nicholls DG. 2007. ATP synthesis capacity, rather than reactive oxygen species, determines the susceptibility of cultured cerebellar granule neurons to glutamate excitotoxicity following 'mild uncoupling'. J Neurochem (in press).
-
(2007)
J Neurochem
-
-
Johnson-Cadwell, L.I.1
Jekabsons, M.B.2
Wang, A.3
Polster, B.M.4
Nicholls, D.G.5
-
12
-
-
0035577283
-
Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane
-
Keelan J, Allen NJ, Antcliffe D, Pal S, Duchen MR. 2001. Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane. J Neurosci Res 66:873-884.
-
(2001)
J Neurosci Res
, vol.66
, pp. 873-884
-
-
Keelan, J.1
Allen, N.J.2
Antcliffe, D.3
Pal, S.4
Duchen, M.R.5
-
13
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, Starkov AA. 1997. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 416:15-18.
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
15
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton P. 1999. Ischemic cell death in brain neurons. Physiol Rev 79:1431-1568.
-
(1999)
Physiol Rev
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
16
-
-
0346788896
-
Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling
-
Miwa S, Brand MD. 2003. Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. Biochem Soc Trans 31:1300-1301.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1300-1301
-
-
Miwa, S.1
Brand, M.D.2
-
17
-
-
33746101420
-
Proton leak induced by reactive oxygen species produced during in vitro anoxia/reoxygenation in rat skeletal muscle mitochondria
-
Navet R, Mouithys-Mickalad A, Douette P, Sluse-Goffart CM, Jarmuszkiewicz W, Sluse FE. 2006. Proton leak induced by reactive oxygen species produced during in vitro anoxia/reoxygenation in rat skeletal muscle mitochondria. J Bioenerg Biomembr 38:23-32.
-
(2006)
J Bioenerg Biomembr
, vol.38
, pp. 23-32
-
-
Navet, R.1
Mouithys-Mickalad, A.2
Douette, P.3
Sluse-Goffart, C.M.4
Jarmuszkiewicz, W.5
Sluse, F.E.6
-
18
-
-
0016294206
-
The influence of respiration and ATP hydrolysis on the proton electrochemical potential gradient across the inner membrane of rat liver mitochondria as determined by ion distribution
-
Nicholls DG. 1974. The influence of respiration and ATP hydrolysis on the proton electrochemical potential gradient across the inner membrane of rat liver mitochondria as determined by ion distribution. Eur J Biochem 50:305-315.
-
(1974)
Eur J Biochem
, vol.50
, pp. 305-315
-
-
Nicholls, D.G.1
-
19
-
-
0017638174
-
The effective proton conductances of the inner membrane of mitochondria from brown adipose tissue: Dependency on proton electrochemical gradient
-
Nicholls DG. 1977. The effective proton conductances of the inner membrane of mitochondria from brown adipose tissue: dependency on proton electrochemical gradient. Eur J Biochem 77:349-356.
-
(1977)
Eur J Biochem
, vol.77
, pp. 349-356
-
-
Nicholls, D.G.1
-
20
-
-
33744952060
-
Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons
-
Nicholls DG. 2006a. Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons. J Biol Chem 281:14864-14874.
-
(2006)
J Biol Chem
, vol.281
, pp. 14864-14874
-
-
Nicholls, D.G.1
-
21
-
-
33745615380
-
The physiological regulation of uncoupling proteins
-
Nicholls DG. 2006b. The physiological regulation of uncoupling proteins. Biochim Biophys Acta 1757:459-466.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 459-466
-
-
Nicholls, D.G.1
-
22
-
-
0033971898
-
Mitochondria and neuronal survival
-
Nicholls DG, Budd SL. 2000. Mitochondria and neuronal survival. Physiol Rev 80:315-360.
-
(2000)
Physiol Rev
, vol.80
, pp. 315-360
-
-
Nicholls, D.G.1
Budd, S.L.2
-
23
-
-
0042035647
-
Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells
-
Nicholls DG, Vesce S, Kirk L, Chalmers S. 2003. Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells. Cell Calc 34:407-424.
-
(2003)
Cell Calc
, vol.34
, pp. 407-424
-
-
Nicholls, D.G.1
Vesce, S.2
Kirk, L.3
Chalmers, S.4
-
24
-
-
0034176843
-
Mitochondrial membrane potential and cell death: Mortality and millivolts
-
Nicholls DG, Ward MW. 2000. Mitochondrial membrane potential and cell death: mortality and millivolts. Trends Neurosci 23:166-174.
-
(2000)
Trends Neurosci
, vol.23
, pp. 166-174
-
-
Nicholls, D.G.1
Ward, M.W.2
-
25
-
-
0023895734
-
Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
-
Novelli A, Reilly JA, Lysko PG, Henneberry RC. 1988. Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res 451:205-212.
-
(1988)
Brain Res
, vol.451
, pp. 205-212
-
-
Novelli, A.1
Reilly, J.A.2
Lysko, P.G.3
Henneberry, R.C.4
-
26
-
-
0041196069
-
Metalloporphyrin class of therapeutic catalytic antioxidants
-
Patel M, Day BJ. 1999. Metalloporphyrin class of therapeutic catalytic antioxidants. Trends Pharmacol Sci 20:359-364.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 359-364
-
-
Patel, M.1
Day, B.J.2
-
27
-
-
0026608995
-
Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
-
Randall RD, Thayer SA. 1992. Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J Neurosci 12:1882-1895.
-
(1992)
J Neurosci
, vol.12
, pp. 1882-1895
-
-
Randall, R.D.1
Thayer, S.A.2
-
28
-
-
0141705360
-
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: Implications for the pathogenesis of neurodegenerative diseases
-
Rego AC, Oliveira CR. 2003. Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: Implications for the pathogenesis of neurodegenerative diseases. Neurochem Res 28:1563-1574.
-
(2003)
Neurochem Res
, vol.28
, pp. 1563-1574
-
-
Rego, A.C.1
Oliveira, C.R.2
-
29
-
-
0029064518
-
Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
-
Reynolds IJ, Hastings TG. 1995. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 15:3318-3327.
-
(1995)
J Neurosci
, vol.15
, pp. 3318-3327
-
-
Reynolds, I.J.1
Hastings, T.G.2
-
30
-
-
0034650763
-
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
-
Ricquier D, Bouillaud F. 2000. The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem J 345:161-179.
-
(2000)
Biochem J
, vol.345
, pp. 161-179
-
-
Ricquier, D.1
Bouillaud, F.2
-
31
-
-
0034688312
-
Glutamate release in severe brain ischaemia is mainly by reversed uptake
-
Rossi DJ, Oshima T, Attwell DA. 2000. Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403:316-321.
-
(2000)
Nature
, vol.403
, pp. 316-321
-
-
Rossi, D.J.1
Oshima, T.2
Attwell, D.A.3
-
32
-
-
0031869004
-
NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: Role of mitochondria
-
Sengpiel B, Preis E, Krieglstein J, Prehn JHM. 1998. NMDA-induced superoxide production and neurotoxicity in cultured rat hippocampal neurons: role of mitochondria. Eur J Neurosci 10:1903-1910.
-
(1998)
Eur J Neurosci
, vol.10
, pp. 1903-1910
-
-
Sengpiel, B.1
Preis, E.2
Krieglstein, J.3
Prehn, J.H.M.4
-
33
-
-
33744915836
-
UCP1 and defense against oxidative stress: 4-Hydroxy-2-nonenal effects on brown-fat mitochondria are uncoupling protein 1-independent
-
Shabalina IG, Petrovic N, Kramarova TV, Hoeks J, Cannon B, Nedergaard J. 2006. UCP1 and defense against oxidative stress: 4-Hydroxy-2-nonenal effects on brown-fat mitochondria are uncoupling protein 1-independent. J Biol Chem 281:13882-13893.
-
(2006)
J Biol Chem
, vol.281
, pp. 13882-13893
-
-
Shabalina, I.G.1
Petrovic, N.2
Kramarova, T.V.3
Hoeks, J.4
Cannon, B.5
Nedergaard, J.6
-
34
-
-
0344198025
-
Mechanism of toxicity in rotenone models of Parkinson's disease
-
Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, Miller GW, Yagi T, Matsuno-Yagi A, Greenamyre JT. 2003. Mechanism of toxicity in rotenone models of Parkinson's disease. J Neurosci 23:10756-10764.
-
(2003)
J Neurosci
, vol.23
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
35
-
-
0042433242
-
2 production by membrane potential and NAD(P)H redox state
-
2 production by membrane potential and NAD(P)H redox state. J Neurochem 86:1101-1107.
-
(2003)
J Neurochem
, vol.86
, pp. 1101-1107
-
-
Starkov, A.A.1
Fiskum, G.2
-
36
-
-
0032150860
-
Glutamate-induced neuron death requires mitochondrial calcium uptake
-
Stout AK, Raphael HM, Kanterewicz BI, Klann E, Reynolds IJ. 1998. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nat Neurosci 1:366-373.
-
(1998)
Nat Neurosci
, vol.1
, pp. 366-373
-
-
Stout, A.K.1
Raphael, H.M.2
Kanterewicz, B.I.3
Klann, E.4
Reynolds, I.J.5
-
37
-
-
33644688266
-
Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons
-
Vesce S, Jekabsons MB, Johnson-Cadwell LI, Nicholls DG. 2005. Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J Biol Chem 280:38720-38728.
-
(2005)
J Biol Chem
, vol.280
, pp. 38720-38728
-
-
Vesce, S.1
Jekabsons, M.B.2
Johnson-Cadwell, L.I.3
Nicholls, D.G.4
-
38
-
-
3342941452
-
Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate
-
Vesce S, Kirk L, Nicholls DG. 2004. Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate. J Neurochem 90:683-693.
-
(2004)
J Neurochem
, vol.90
, pp. 683-693
-
-
Vesce, S.1
Kirk, L.2
Nicholls, D.G.3
-
39
-
-
0000434165
-
2+ loads by mitochondria in cultured rat hippocampal neurons
-
2+ loads by mitochondria in cultured rat hippocampal neurons. J Neurophysiol 76:1611-1621.
-
(1996)
J Neurophysiol
, vol.76
, pp. 1611-1621
-
-
Wang, G.J.1
Thayer, S.A.2
-
40
-
-
0034307759
-
Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
-
Ward MW, Rego AC, Frenguelli BG, Nicholls DG. 2000. Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 20:7208-7219.
-
(2000)
J Neurosci
, vol.20
, pp. 7208-7219
-
-
Ward, M.W.1
Rego, A.C.2
Frenguelli, B.G.3
Nicholls, D.G.4
|