High DNA affinity of a series of peptide linked diaromatic guanidinium-like derivatives

Journal of Medicinal Chemistry

Volumn 55, Issue 9, 2012, Pages 4397-4406

  Nagle, Padraic S ^a   Rodriguez, Fernando ^a,c   Nguyen, Binh ^b,d   Wilson, W David ^b   Rozas, Isabel ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF LA RIOJA   (Spain)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOIMIDAZOLINIUM; 4 ( 2 AMINOIMIDAZOLINO) N ( 4 GUANIDINOPHENYL)BENZAMIDE; AT OLIGONUCLEOTIDE; BENZAMIDE DERIVATIVE; DNA; GUANIDINE; GUANIDINE DERIVATIVE; IMIDAZOLE DERIVATIVE; OLIGONUCLEOTIDE; PEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOPHYSICS; CIRCULAR DICHROISM; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; DENATURATION; DNA BINDING; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENTHALPY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; STOICHIOMETRY; SURFACE PLASMON RESONANCE; THERMAL ANALYSIS; THERMAL DENATURATION; THERMODYNAMICS;

CALORIMETRY; CATIONS; CIRCULAR DICHROISM; DNA; GUANIDINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PEPTIDES; PROTEIN BINDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 84861052192     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300296f     Document Type: Article

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