Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove

Biophysical Chemistry

Volumn 131, Issue 1-3, 2007, Pages 1-14

  Liu, Yang ^a   Kumar, Arvind ^a   Boykin, David W ^a   Wilson, W David ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Alternating and nonalternating AT DNAs; Biosensor surface plasmon resonance; DB75; Differential scanning calorimetry; Isothermal titration microcalorimetry; Thermodynamics

Indexed keywords

2,5 BIS(4 AMIDINOPHENYL)FURAN; ANTIPARASITIC AGENT; DIAMIDINE DERIVATIVE; HETEROCYCLIC AMINE; OLIGOMER; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; BIOSENSOR; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING; ENTHALPY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; THERMODYNAMICS;

ANTIPARASITIC AGENTS; BASE SEQUENCE; BENZAMIDINES; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; DNA; PENTAMIDINE; POLY DA-DT; THERMODYNAMICS; ULTRAVIOLET RAYS;

EID: 35648989558     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2007.08.007     Document Type: Article

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