Design of DNA minor groove binding diamidines that recognize GC base pair sequences: A dimeric-hinge interaction motif

Journal of the American Chemical Society

Volumn 129, Issue 44, 2007, Pages 13732-13743

  Munde, Manoj ^a   Ismail, Mohamed A ^a   Arafa, Reem ^a   Peixoto, Paul ^b   Collar, Catharine J ^a   Liu, Yang ^a   Hu, Laixing ^a   David Cordonnier, Marie Hélène ^b   Lansiaux, Amélie ^b,c   Bailly, Christian ^b,d   Boykin, David W ^a   Wilson, W David ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^c CENTRE OSCAR LAMBRET   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DIMERS; MATHEMATICAL MODELS; NITROGEN;

BIOLOGICAL EFFECTS; GROOVE BINDING; TRIPHENYL DIAMIDINE;

DNA;

BENZENE DERIVATIVE; CYTOSINE; DEOXYRIBONUCLEASE I; DIAMIDINE DERIVATIVE; GUANINE; HETEROCYCLIC COMPOUND; POLYAMIDE; PYRIMIDINE;

ARTICLE; BASE PAIRING; BINDING SITE; CIRCULAR DICHROISM; DNA BINDING; DNA FOOTPRINTING; DNA HYBRIDIZATION; DNA SEQUENCE; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; PROTEIN MOTIF; SEQUENCE ANALYSIS;

AMINO ACID MOTIFS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; BIOSENSING TECHNIQUES; CALORIMETRY; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PENTAMIDINE; SENSITIVITY AND SPECIFICITY; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 35948967317     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja074560a     Document Type: Article

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