Polyamide curvature and DNA sequence selective recognition: Use of 4-aminobenzamide to adjust curvature

Medicinal Chemistry

Volumn 5, Issue 3, 2009, Pages 216-226

  Lajiness, Jamie ^a   Sielaff, Alan ^a   Mackay, Hilary ^a   Brown, Toni ^a   Kluza, Jerome ^b   Nguyen, Binh ^c   Wilson, W David ^c   Lee, Moses ^a   Hartley, John A ^b  

^a HOPE COLLEGE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Curvature; DNA; Gene regulation; Minor groove; Polyamide

Indexed keywords

2,5 BIS(4 AMIDINOPHENYL)FURAN; 4 AMINOBENZAMIDE; BENZENE DERIVATIVE; DISTAMYCIN A; DNA; IMIDAZOLE DERIVATIVE; POLYAMIDE; PYRROLE DERIVATIVE; 4 AMINOBENZOIC ACID; 4-AMINOBENZAMIDE; DEOXYRIBONUCLEASE I; DRUG DERIVATIVE; NYLON;

ARTICLE; BINDING AFFINITY; CELL DIVISION; CIRCULAR DICHROISM; DENATURATION; DNA FOOTPRINTING; DNA SEQUENCE; DRUG DESIGN; DRUG DNA BINDING; DRUG SYNTHESIS; DRUG TARGETING; GENE EXPRESSION; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MODEL; PRIORITY JOURNAL; PROMOTER REGION; SURFACE PLASMON RESONANCE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA DENATURATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; TRANSITION TEMPERATURE;

4-AMINOBENZOIC ACID; BASE SEQUENCE; CALORIMETRY; CIRCULAR DICHROISM; DEOXYRIBONUCLEASE I; DNA; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEIC ACID DENATURATION; NYLONS; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE; TRANSITION TEMPERATURE;

EID: 67651173083     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340609788185945     Document Type: Article

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