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Volumn 28, Issue 3, 2012, Pages 316-320

Aging and the control of the insulin-FOXO signaling pathway;Bien vieillir: La voie de signalisation insuline-FOXO et la longévité

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; FORKHEAD TRANSCRIPTION FACTOR; INSULIN; SOMATOMEDIN C;

EID: 84860805838     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2012283021     Document Type: Review
Times cited : (11)

References (42)
  • 1
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • DOI 10.1038/366461a0
    • Kenyon C, Chang J, Gensch E, et al. A C. elegans mutant that lives twice as long as wild type. Nature 1993;366:461-4. (Pubitemid 24013878)
    • (1993) Nature , vol.366 , Issue.6454 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 2
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon CJ. The genetics of ageing. Nature 2010;464:504-12.
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 3
    • 0035815445 scopus 로고    scopus 로고
    • A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
    • DOI 10.1126/science.1057987
    • Tatar M, Kopelman A, Epstein D, et al. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 2001;292:107-10. (Pubitemid 32289137)
    • (2001) Science , vol.292 , Issue.5514 , pp. 107-110
    • Tatar, M.1    Kopelman, A.2    Epstein, D.3    Tu, M.-P.4    Yin, C.-M.5    Garofalo, R.S.6
  • 6
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • DOI 10.1126/science.1078223
    • Bluher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 2003;299:572-4. (Pubitemid 36135156)
    • (2003) Science , vol.299 , Issue.5606 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 7
    • 71449108913 scopus 로고    scopus 로고
    • Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
    • Cohen E, Paulsson JF, Blinder P, et al. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice. Cell 2009;139:1157-69.
    • (2009) Cell , vol.139 , pp. 1157-1169
    • Cohen, E.1    Paulsson, J.F.2    Blinder, P.3
  • 9
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • DOI 10.1038/sj.onc.1209086, PII 1209086
    • Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005;24:7410-25. (Pubitemid 41637981)
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 10
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • DOI 10.1128/MCB.21.3.952-965.2001
    • Brunet A, Park J, Tran H, et al. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 2001;21:952-65. (Pubitemid 32104742)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.3 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 15
    • 0037136563 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    • Kops GJ, Dansen TB, Polderman PE, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002;419:316-21.
    • (2002) Nature , vol.419 , pp. 316-321
    • Kops, G.J.1    Dansen, T.B.2    Polderman, P.E.3
  • 16
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27(kip1)
    • DOI 10.1038/35008115
    • Medema RH, Kops GJ, Bos JL, Burgering BM. AFX-like Forkhead transcription factors mediate cellcycle regulation by Ras and PKB through p27kip1. Nature 2000;404:782-7. (Pubitemid 30212408)
    • (2000) Nature , vol.404 , Issue.6779 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.P.L.2    Bos, J.L.3    Burgering, B.M.T.4
  • 17
    • 0037192473 scopus 로고    scopus 로고
    • Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
    • DOI 10.1126/science.1069004
    • Nemoto S, Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 2002;295:2450-2. (Pubitemid 34270258)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2450-2452
    • Nemoto, S.1    Finkel, T.2
  • 18
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 2003;424:277-83.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3
  • 19
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • DOI 10.1038/onc.2008.21, PII ONC200821
    • Calnan DR, Brunet A. The FoxO code. Oncogene 2008;27:2276-88. (Pubitemid 351501779)
    • (2008) Oncogene , vol.27 , Issue.16 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 21
  • 25
    • 79960715027 scopus 로고    scopus 로고
    • The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
    • Renault VM, Thekkat PU, Hoang KL, et al. The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene 2011;30:3207-21.
    • (2011) Oncogene , vol.30 , pp. 3207-3221
    • Renault, V.M.1    Thekkat, P.U.2    Hoang, K.L.3
  • 26
    • 2942563805 scopus 로고    scopus 로고
    • Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
    • DOI 10.1038/nature02549
    • Hwangbo DS, Gershman B, Tu MP, et al. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 2004;429:562-6. (Pubitemid 38737660)
    • (2004) Nature , vol.429 , Issue.6991 , pp. 562-566
    • Hwangbo, D.S.1    Garsham, B.2    Tu, M.-P.3    Palmer, M.4    Tatar, M.5
  • 28
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • DOI 10.1016/S0960-9822(01)00594-2
    • Henderson ST, Johnson TE. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 2001;11:1975-80. (Pubitemid 33146425)
    • (2001) Current Biology , vol.11 , Issue.24 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 29
    • 52949122885 scopus 로고    scopus 로고
    • FOXO3A genotype is strongly associated with human longevity
    • Willcox BJ, Donlon TA, He Q, et al. FOXO3A genotype is strongly associated with human longevity. Proc Natl Acad Sci USA 2008;105:13987-92.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13987-13992
    • Willcox, B.J.1    Donlon, T.A.2    He, Q.3
  • 30
    • 67651151249 scopus 로고    scopus 로고
    • Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
    • Pawlikowska L, Hu D, Huntsman S, et al. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell 2009;8:460-72.
    • (2009) Aging Cell , vol.8 , pp. 460-472
    • Pawlikowska, L.1    Hu, D.2    Huntsman, S.3
  • 31
    • 62449083712 scopus 로고    scopus 로고
    • Association of FOXO3A variation with human longevity confirmed in German centenarians
    • Flachsbart F, Caliebe A, Kleindorp R, et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci USA 2009;106:2700-5.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2700-2705
    • Flachsbart, F.1    Caliebe, A.2    Kleindorp, R.3
  • 32
    • 66149172131 scopus 로고    scopus 로고
    • Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study
    • Anselmi CV, Malovini A, Roncarati R, et al. Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. Rejuvenation Res 2009;12:95-104.
    • (2009) Rejuvenation Res , vol.12 , pp. 95-104
    • Anselmi, C.V.1    Malovini, A.2    Roncarati, R.3
  • 33
    • 70350359126 scopus 로고    scopus 로고
    • Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations
    • Li Y, Wang WJ, Cao H, et al. Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet 2009;18:4897-904.
    • (2009) Hum Mol Genet , vol.18 , pp. 4897-4904
    • Li, Y.1    Wang, W.J.2    Cao, H.3
  • 35
    • 34547660196 scopus 로고    scopus 로고
    • FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
    • DOI 10.1016/j.stem.2007.07.017, PII S1934590907000835
    • Tothova Z, Gilliland DG. FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system. Cell Stem Cell 2007;1:140-52. (Pubitemid 47215597)
    • (2007) Cell Stem Cell , vol.1 , Issue.2 , pp. 140-152
    • Tothova, Z.1    Gilliland, D.G.2
  • 36
    • 70350497348 scopus 로고    scopus 로고
    • FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
    • Paik JH, Ding Z, Narurkar R, et al. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell 2009;5:540-53.
    • (2009) Cell Stem Cell , vol.5 , pp. 540-553
    • Paik, J.H.1    Ding, Z.2    Narurkar, R.3
  • 38
    • 80052490840 scopus 로고    scopus 로고
    • FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
    • Zhang X, Yalcin S, Lee DF, et al. FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat Cell Biol 2011;13:1092-9.
    • (2011) Nat Cell Biol , vol.13 , pp. 1092-1099
    • Zhang, X.1    Yalcin, S.2    Lee, D.F.3
  • 39
    • 16544372373 scopus 로고    scopus 로고
    • Les multiples actions des facteurs de transcription Foxo
    • Brunet A. Les multiples actions des facteurs de transcription Foxo. Med Sci (Paris) 2004;20:856-9.
    • (2004) Med Sci (Paris) , vol.20 , pp. 856-859
    • Brunet, A.1
  • 40
    • 70349234500 scopus 로고    scopus 로고
    • Les récepteurs centraux de l'IGF-1 contôlent la longévité chez la souris
    • Holzenberger M. Les récepteurs centraux de l'IGF-1 contôlent la longévité chez la souris. Med Sci (Paris) 2009;25:371-6.
    • (2009) Med Sci (Paris) , vol.25 , pp. 371-376
    • Holzenberger, M.1
  • 41
    • 34249722632 scopus 로고    scopus 로고
    • FoxO: Stress vie éternelle
    • Tothova Z, Mercher T. FoxO: stress vie éternelle. Med Sci (Paris) 2007;23:466-7.
    • (2007) Med Sci (Paris) , vol.23 , pp. 466-467
    • Tothova, Z.1    Mercher, T.2
  • 42
    • 84860798479 scopus 로고    scopus 로고
    • Rôle des facteurs de transcription FoxO dans la maintenance des cellules souches
    • Rimmelé P, Zhang Y, Ghaffari S. Rôle des facteurs de transcription FoxO dans la maintenance des cellules souches. Med Sci (Paris) 2012;28:250-4.
    • (2012) Med Sci (Paris) , vol.28 , pp. 250-254
    • Rimmelé, P.1    Zhang, Y.2    Ghaffari, S.3


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