The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

Oncogene

Volumn 30, Issue 29, 2011, Pages 3207-3221

  Renault, V M ^a   Thekkat, P U ^a   Hoang, K L ^a   White, J L ^a   Brady, C A ^a   Kenzelmann Broz, D ^a   Venturelli, O S ^a   Johnson, T M ^a   Oskoui, P R ^a   Xuan, Z ^b   Santo, E E ^c   Zhang, M Q ^b,d   Vogel, H ^e   Attardi, L D ^a   Brunet, A ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d TSINGHUA UNIVERSITY   (China)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

aging; cancer; FoxO transcription factors; longevity; p53; tumor suppression

Indexed keywords

PROTEIN P53; TRANSCRIPTION FACTOR FKHRL1;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CELL CYCLE ARREST; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GENE EXPRESSION REGULATION; GENE TARGETING; IN VIVO STUDY; LONGEVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THYMOCYTE; TISSUE SPECIFICITY; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL CYCLE; CELLS, CULTURED; DNA DAMAGE; DNA PRIMERS; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; IMIDAZOLES; LONGEVITY; MICE; PIPERAZINES; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

MAMMALIA; MUS;

EID: 79960715027     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.35     Document Type: Article

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