The fast release of sticky protons: Kinetics of substrate binding and proton release in a multidrug transporter

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 46, 2007, Pages 17989-17994

  Adam, Yoav ^a   Tayer, Naama ^a   Rotem, Dvir ^a,c   Schreiber, Gideon ^b   Schuldiner, Shimon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Drug; Fluorescence; Ion coupled transporter; Membrane protein; Resistance; Transient kinetic

Indexed keywords

GLYCOPROTEIN P; PROTEIN EMRE; PROTON; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FLUORESCENCE; KINETICS; NONHUMAN; PH; PRIORITY JOURNAL;

AMINO ACIDS; ANTIPORTERS; BINDING SITES; ESCHERICHIA COLI PROTEINS; HYDROGEN-ION CONCENTRATION; KINETICS; PROTEIN BINDING; PROTONS; SPECTROMETRY, FLUORESCENCE;

ESCHERICHIA COLI HS;

EID: 36749095723     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0704425104     Document Type: Article

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