In vitro - In vivo correlation of gene expression alterations induced by liver carcinogens

Current Medicinal Chemistry

Volumn 19, Issue 11, 2012, Pages 1721-1730

  Heise, T ^a   Schug, M ^b   Storm, D ^a   Ellinger Ziegelbauer, H ^c   Ahr, H J ^c   Hellwig, B ^d   Rahnenfuhrer J ^d   Ghallab, A ^b   Guenther, G ^b   Sisnaiske, J ^b   Reif, R ^b   Godoy, P ^b   Mielke, H ^a   Gundert Remy, U ^a   Lampen, A ^a   Oberemm, A ^a   Hengstler, J G ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^c BAYER PHARMA AG   (Germany)

^d TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Carcinogens; Genotoxic; Hepatocytes; In vitro; Non genotoxic; Proliferation; Sandwich culture; Stress response genes; Toxicogenomics

Indexed keywords

2 NITROFLUORENE; AFLATOXIN B1; METHAPYRILENE; PIPERONYL BUTOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METABOLISM; DNA REPAIR; GENE EXPRESSION; GENETIC ASSOCIATION; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER CELL; MALE; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS;

AFLATOXIN B1; ANIMALS; CARCINOGENS; CELL PROLIFERATION; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; DOWN-REGULATION; FLUORENES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; LIVER; MALE; METHAPYRILENE; PIPERONYL BUTOXIDE; RATS; RATS, WISTAR; STRESS, PHYSIOLOGICAL; UP-REGULATION;

EID: 84860535481     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712799945049     Document Type: Article

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