Long term cultures of primary human hepatocytes as an alternative to drug testing in animals

Altex

Volumn 26, Issue 4, 2009, Pages 295-302

  Ullrich, Anett ^a   Stolz, Donna B ^b   Ellis, Ewa C ^c   Strom, Stephen C ^c   Michalopoulos, George K ^c   Hengstler, Jan G ^d   Runge, Dieter ^a  

^a PRIMACYT Cell Culture Technology GmbH   (Germany)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

Author keywords

Acetaminophen; Animal studies; Drug testing; Human hepatocytes

Indexed keywords

ALBUMIN; GLYCOGEN; LACTATE DEHYDROGENASE; PARACETAMOL; UREA; ALBUMINOID;

ARTICLE; CELL CULTURE; CELL FUNCTION; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG SCREENING; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; LIVER CELL; PROTEIN DEGRADATION; ANIMAL TESTING ALTERNATIVE; CULTURE MEDIUM; CULTURE TECHNIQUE; DRUG EFFECT; METABOLISM; METHODOLOGY; PHYSIOLOGY; TIME; ULTRASTRUCTURE;

ACETAMINOPHEN; ALBUMINS; ANIMAL TESTING ALTERNATIVES; CELL CULTURE TECHNIQUES; CULTURE MEDIA, SERUM-FREE; GLYCOGEN; HEPATOCYTES; HUMANS; L-LACTATE DEHYDROGENASE; TIME FACTORS; UREA;

EID: 79952196937     PISSN: 09467785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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