Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner

Biochemical and Biophysical Research Communications

Volumn 394, Issue 4, 2010, Pages 915-920

  Ilowski, Maren ^a   Putz, Christine ^a   Weiss, Thomas S ^b   Brand, Stephan ^a   Jauch, Karl Walter ^a   Hengstler, Jan G ^c   Thasler, Wolfgang Erwin ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c TU DORTMUND UNIVERSITY   (Germany)

Author keywords

AKT PKB; Augmenter of liver regeneration; ERK1 2; Human hepatocytes; Liver regeneration; Liver specificity

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; AUGMENTER OF LIVER REGENERATION; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; RECOMBINANT GROWTH FACTOR; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BRONCHUS; CELL LINE; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL TYPE; COLON; HUMAN; HUMAN CELL; KINETICS; LIVER CELL; LIVER REGENERATION; PANCREAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STOMACH;

CELL LINE; CELL PROLIFERATION; CYTOCHROME REDUCTASES; EPIDERMAL GROWTH FACTOR; HEPATOCYTES; HUMANS; LIVER; LIVER REGENERATION; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 77950858251     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.03.074     Document Type: Article

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