Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1

Oncogene

Volumn 31, Issue 12, 2012, Pages 1582-1591

  Gaude, H ^a   Aznar, N ^a   Delay, A ^a   Bres, A ^a   Buchet Poyau, K ^a   Caillat, C ^b   Vigouroux, A ^b   Rogon, C ^c   Woods, A ^d   Vanacker, J M ^e   Hohfeld J ^c   Perret, C ^f   Meyer, P ^b   Billaud, M ^g   Forcet, C ^e  

^a CNRS   (France)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^c UNIVERSITY OF BONN   (Germany)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e UNIVERSITÉ LYON 1   (France)

^f INSTITUT COCHIN   (France)

^g INSTITUT ALBERT BONNIOT   (France)

Author keywords

chaperones; CHIP; Hsp90; LKB1; tumor suppressor

Indexed keywords

CELL CYCLE PROTEIN 37; CHAPERONE; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 90; MULTIPROTEIN COMPLEX; PROTEIN; PROTEIN KINASE LKB1; PROTEIN STRAD; RECOMBINANT PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOCATALYSIS; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; ENZYME STABILITY; GENE ACTIVITY; GENE DISRUPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; RNA INTERFERENCE; TUMOR SUPPRESSOR GENE;

CELL CYCLE PROTEINS; CHAPERONINS; ENZYME STABILITY; HSC70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; MULTIENZYME COMPLEXES; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84860407614     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.342     Document Type: Article

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