Characterization of celastrol to inhibit Hsp90 and Cdc37 interaction

Journal of Biological Chemistry

Volumn 284, Issue 51, 2009, Pages 35381-35389

  Zhang, Tao ^a   Li, Yanyan ^a   Yu, Yanke ^a   Zou, Peng ^a   Jiang, Yiqun ^a   Sun, Duxin ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP BINDING; ATP-ASE ACTIVITY; C TERMINUS; C-TERMINAL DOMAINS; CANCER TREATMENT; CHAPERONE ACTIVITY; COMPLEX FORMATIONS; ELISA ASSAY; GELDANAMYCIN; GST PULL-DOWN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONES; ONCOGENIC PROTEINS; PROTEIN KINASE; PROTEIN SYSTEM; TRYPSIN DIGESTION;

DRUG INTERACTIONS;

PROTEINS;

CELASTROL; CELL CYCLE PROTEIN 37; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; TRYPSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; CELL CYCLE PROTEINS; CELL-FREE SYSTEM; CHAPERONINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MULTIPROTEIN COMPLEXES; NEOPLASM PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRITERPENES;

EID: 72149125851     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.051532     Document Type: Article

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