Effect of synthetic Aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Lioudyno, Maria I ^a   Broccio, Matteo ^b   Sokolov, Yuri ^a   Rasool, Suhail ^c   Wu, Jessica ^c   Alkire, Michael T ^a   Liu, Virginia ^a   Kozak, J Ashot ^d   Dennison, Philip R ^c   Glabe, Charles G ^c   Lösche, Mathias ^b,e,f   Hall, James E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WRIGHT STATE UNIVERSITY   (United States)

^e NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^f CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN[1-42]; FLUORINE; HEXAFLUORO 2 PROPANOL; MONOMER; OLIGOMER; POTASSIUM CHANNEL KV1.3; SODIUM HYDROXIDE; SOLVENT; TRIFLUOROACETIC ACID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; PROPANOL;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; ENZYME KINETICS; FLUORINATION; LIGHT SCATTERING; LIPID BILAYER; LYOPHILISATE; MEMBRANE CONDUCTANCE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATCH CLAMP; PROTEIN CONFORMATION; STEADY STATE; ARTIFICIAL MEMBRANE; CHEMISTRY; ELECTRIC CONDUCTIVITY; HALOGENATION; KINETICS; LIGHT; METABOLISM; RADIATION SCATTERING; SYNTHESIS;

AMYLOID BETA-PEPTIDES; ELECTRIC CONDUCTIVITY; HALOGENATION; KINETICS; KV1.3 POTASSIUM CHANNEL; LIGHT; LIPID BILAYERS; MEMBRANES, ARTIFICIAL; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PROPANOLS; SCATTERING, RADIATION; SODIUM HYDROXIDE; SOLVENTS;

EID: 84860356517     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035090     Document Type: Article

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