Presence of the voltage-gated potassium channels sensitive to charybdotoxin in inhibitory presynaptic terminals of cultured rat hippocampal neurons

Neuroscience Letters

Volumn 207, Issue 3, 1996, Pages 195-198

  Ohno Shosaku, Takako ^a   Kim, Insook ^b   Sawada, Satsuki ^a   Yamamoto, Chosaburo ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF LOUISIANA AT LAFAYETTE   (United States)

Author keywords

Charybdotoxin; Hippocampus; Inhibitory synapse; Kv1.3; Presynaptic terminal; Voltage gated K+ channel

Indexed keywords

CHARYBDOTOXIN; IBERIOTOXIN; KALIOTOXIN; MARGATOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; NERVE CELL; NEWBORN; NONHUMAN; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT;

EID: 0029919289     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12518-0     Document Type: Article

References (20)

1. + channels are modulated by 5-HT1c receptor activation and independently by PKC, Am. J. Physiol., 265 (1993) C1571-C1578.
2. Augustine, G.J., Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current, J. Physiol., 431 (1990) 343-364.
3. Beckh, S. and Pongs, O., Members of the RCK potassium channel family are differentially expressed in the rat nervous system, EMBO J., 9 (1990) 777-782.
4. Blaustein, M.P., Rogowski, R.S., Schneider, M.J. and Krueger, B.K., Polypeptide toxins from the venoms of old world and new world scorpions preferentially block different potassium channels, Mol. Pharmacol., 40 (1991) 932-942.
5. Capogna, M., Gähwiler, B.H. and Thompson, S.M., Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro, J. Neurosci., 15 (1995) 1249-1260.
6. + channels and suppression of neuronal activity by secreted β-amyloid-precursor protein, Nature, 379 (1996) 74-78.
7. Garcia, M.L., Knaus, H.-G., Munujos, P., Slaughter, R.S. and Kaczorowski, G.J., Charybdotoxin and its effects on potassium channels, Am. J. Physiol., 269 (1995) C1-C10.
8. + channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines, Mol. Pharmacol., 45 (1994) 1227-1234.
9. Lancaster, B. and Nicoll, R.A., Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones, J. Physiol., 389 (1987) 187-203.
10. Morita, K. and Barrett, E.F., Evidence for two calcium-dependent potassium conductances in lizard motor nerve terminals, J. Neurosci., 10 (1990) 2614-2625.
11. North, R.A., Ligand-and voltage-gated ion channels, CRC Press, Boca Raton, USA, 1995, pp. 1-72.
12. + channel activators suppress the GABAergic inhibitory transmission by acting both presynaptic and postsynaptic sites in rat cultured hippocampal neurons, Neurosci. Lett., 159 (1993) 139-142.
13. Ohno-Shosaku, T., Hirata, K., Sawada, S. and Yamamoto, C., Contributions of multiple calcium channel types to GABAergic transmission in rat cultured hippocampal neurons, Neurosci. Lett., 181 (1994) 145-148.
14. Robitaille, R. and Charlton, M.P., Presynaptic calcium signals and transmitter release are modulated by calcium-activated potassium channels, J. Neurosci., 12 (1992) 297-305.
15. Ropert, N. and Guy, N., Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro, J. Physiol., 441 (1991) 121-136.
16. + channels detected in vivo, Nature, 365 (1993) 72-75.
17. Sladeczek, F., Momiyama, A. and Takahashi, T., Presynaptic inhibitory action of a metabotropic glutamate receptor agonist on excitatory transmission in visual cortical neurons, Proc. R. Soc. Lond. B, 253 (1993) 297-303.
18. Vázquez, J., Feigenbaum, P., King, V.F., Kaczorowski, G.J. and Garcia, M.L., Characterization of high affinity binding sites for charybdotoxin in synaptic plasma membranes from rat brain, J. Biol. Chem., 265 (1990) 15564-15571.
19. Wang, H., Kunkel, D.D., Schwartzkroin, P.A. and Tempel, B.L, Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain, J. Neurosci., 14 (1994) 4588-4599.
20. Yoshino, M. and Kamiya, H., Suppression of presynaptic calcium influx by metabotropic glutamate receptor agonists in neonatal rat hippocampus, Brain Res., 695 (1995) 179-185.