Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection

Journal of Experimental Medicine

Volumn 205, Issue 10, 2008, Pages 2359-2368

  Gallegos, Alena M ^a   Pamer, Eric G ^a   Glickman, Michael S ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EARLY SECRETORY ANTIGENIC TARGET 6;

ADOPTIVE TRANSFER; AIRBORNE INFECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROTECTION; CONTROLLED STUDY; EFFECTOR CELL; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TUBERCULOSIS;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; HUMANS; MICE; MICE, TRANSGENIC; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL; TH1 CELLS; TIME FACTORS; TUBERCULOSIS;

EID: 53349118087     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20080353     Document Type: Article

References (15)

1. Keane, J., S. Gershon, R.P. Wise, E. Mirabile-Levens, J. Kasznica, W.D. Schwieterman, J.N. Siegel, and M.M. Braun. 2001. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N. Engl. J. Med. 345:1098-1104.
2. Cooper, A.M., D.K. Dalton, T.A. Stewart, J.P. Griffin, D.G. Russell, and I.M. Orme. 1993. Disseminated tuberculosis in interferon γ gene-disrupted mice. J. Exp. Med. 178:2243-2247.
3. Flynn, J.L., J. Chan, K.J. Triebold, D.K. Dalton, T.A. Stewart, and B.R. Bloom. 1993. An essential role for interferon γ in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
4. van de Vosse, E., M.A. Hoeve, and T.H. Ottenhoff. 2004. Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae. Lancet Infect. Dis. 4:739-749.
5. Flynn, J.L., M.M. Goldstein, J. Chan, K.J. Triebold, K. Pfeffer, C.J. Lowenstein, R. Schreiber, T.W. Mak, and B.R. Bloom. 1995. Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity. 2:561-572.
6. North, R.J., and Y.J. Jung. 2004. Immunity to tuberculosis. Annu. Rev. Immunol. 22:599-623.
7. van Rie, A., R. Warren, M. Richardson, T.C. Victor, R.P. Gie, D.A. Enarson, N. Beyers, and P.D. van Helden. 1999. Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment. N. Engl. J. Med. 341:1174-1179.
8. Caminero, J.A., M.J. Pena, M.I. Campos-Herrero, J.C. Rodriguez, O. Afonso, C. Martin, J.M. Pavon, M.J. Torres, M. Burgos, P. Cabrera, et al. 2001. Exogenous reinfection with tuberculosis on a European island with a moderate incidence of disease. Am. J. Respir. Crit. Care Med. 163:717-720.
9. Andersen, P., and T.M. Doherty. 2005. The success and failure of BCG - implications for a novel tuberculosis vaccine. Nat. Rev. Microbiol. 3:656-662.
10. Mogues, T., M.E. Goodrich, L. Ryan, R. LaCourse, and R.J. North. 2001. The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice. J. Exp. Med. 193:271-280.
11. Caruso, A.M., N. Serbina, E. Klein, K. Triebold, B.R. Bloom, and J.L. Flynn. 1999. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. J. Immunol. 162:5407-5416.
12. Tascon, R.E., E. Stavropoulos, K.V. Lukacs, and M.J. Colston. 1998. Protection against Mycobacterium tuberculosis infection by CD8+ T cells requires the production of gamma interferon. Infect. Immun. 66:830-834.
13. Markowitz, N., N.I. Hansen, P.C. Hopewell, J. Glassroth, P.A. Kvale, B.T. Mangura, T.C. Wilcosky, J.M. Wallace, M.J. Rosen, and L.B. Reichman. 1997. Incidence of tuberculosis in the United States among HIV-infected persons. The Pulmonary Complications of HIV Infection Study Group. Ann. Intern. Med. 126:123-132.
14. Khader, S.A., G.K. Bell, J.E. Pearl, J.J. Fountain, J. Rangel-Moreno, G.E. Cilley, F. Shen, S.M. Eaton, S.L. Gaffen, S.L. Swain, et al. 2007. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 8:369-377.
15. Scott-Browne, J.P., S. Shafiani, G. Tucker-Heard, K. Ishida-Tsubota, J.D. Fontenot, A.Y. Rudensky, M.J. Bevan, and K.B. Urdahl. 2007. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. J. Exp. Med. 204:2159-2169.