Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes

FEBS Journal

Volumn 279, Issue 9, 2012, Pages 1534-1544

  Pudney, Christopher R ^a   Heyes, Derren J ^a   Khara, Basile ^a   Hay, Sam ^a   Rigby, Stephen E J ^a   Scrutton, Nigel S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

dynamics; enzyme; flavin; kinetics; P450

Indexed keywords

CYTOCHROME P450 REDUCTASE; DIFLAVIN REDUCTASE; OXIDOREDUCTASE; SEMIQUINONE; UNCLASSIFIED DRUG;

CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; ENZYME KINETICS; ENZYME STRUCTURE; IONIC STRENGTH; NONHUMAN; PRIORITY JOURNAL; PULSED ELECTRON ELECTRON DOUBLE RESONANCE SPECTROSCOPY; REVIEW; SPECTROSCOPY; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VISCOSITY;

ANIMALS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ELECTRON TRANSPORT; FERREDOXIN-NADP REDUCTASE; FLAVIN MONONUCLEOTIDE; HUMANS; KINETICS; MOTION; NADPH-FERRIHEMOPROTEIN REDUCTASE; NITRIC OXIDE SYNTHASE; PROTEIN CONFORMATION; SPECTRUM ANALYSIS;

EID: 84860223079     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08442.x     Document Type: Review

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