Electron transfer by neuronal nitric-oxide synthase is regulated by concerted interaction of calmodulin and two intrinsic regulatory elements

Journal of Biological Chemistry

Volumn 281, Issue 32, 2006, Pages 23111-23118

  Roman, Linda J ^a   Masters, Bettie Sue S ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON TRANSITIONS; GENETIC ENGINEERING; MOLECULAR BIOLOGY; NEURAL NETWORKS; NITROGEN COMPOUNDS; PROTEINS;

AUTOREGULATORY REGION (AR); INTRINSIC REGULATORY ELEMENTS; NITRIC-OXIDE SYNTHASES (NOS); REDUCTASE DOMAIN;

ENZYME KINETICS;

CALMODULIN; CYTOCHROME C; FERRICYANIDE; NEURONAL NITRIC OXIDE SYNTHASE; OXIDOREDUCTASE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SYNTHESIS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; REGULATORY SEQUENCE;

AMINO ACID SEQUENCE; ANIMALS; CALMODULIN; ELECTRONS; GENE DELETION; HEME; MOLECULAR SEQUENCE DATA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33747335659     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603671200     Document Type: Article

References (53)

1. Masters, B. S. S. (2000) in Nitric Oxide, Biology and Pathobiology (Ignarro, L. J., ed) pp. 91-104, Academic Press, New York
2. Roman, L. J., Martásek, P., and Masters, B. S. S. (2002) Chem. Rev. 102, 1179-1190
3. Michel, T., and Feron, O. (1997) J. Clin. Investig. 100, 2146-2152
4. Alderton, W. K., Cooper, C. E., and Knowles, R. G. (2001) Biochem. J. 357, 593-615
5. Stuehr, D. J., Santolini, J., Wang, Z. Q., Wei, C. C., and Adak, S. (2004) J. Biol. Chem. 279, 36167-36170
6. Andrew, P. J., and Mayer, B. (1999) Cardiovasc. Res. 43, 521-531
7. Li, H., and Poulos, T. L. (2005) J. Inorg. Biochem. 99, 293-305
8. Bruckdorfer, R. (2005) Mol. Aspects Med. 26, 3-31
9. Siddhanta, U., Wu, C., Abu-Soud, H. M., Zhang, J., Ghosh, D. K., and Stuehr, D. J. (1996) J. Biol. Chem. 271, 7309-7312
10. Siddhanta, U., Presta, A., Fan, B., Wolan, D., Rousseau, D. L., and Stuehr, D. J. (1998) J. Biol. Chem. 273, 18950-18958
11. Sagami, I., Daff, S., and Shimizu, T. (2001) J. Biol. Chem. 276, 30036-30042
12. Craig, D. H., Chapman, S. K., and Daff, S. (2002) J. Biol. Chem. 277, 33987-33994
13. Ghosh, D. K., and Salerno, J. C. (2003) Front. Biosci. 8, 193-209
14. Knight, K., and Scrutton, N. S. (2002) Biochem. J. 367, 19-30
15. McMillan, K., and Masters, B. S. S. (1995) Biochemistry 34, 3686-3693
16. Sheta, E. A., McMillan, K., and Masters, B. S. S. (1994) J. Biol. Chem. 269, 15147-15153
17. Gachhui, R., Presta, A., Bentley, D. F., Abu-Soud, H. M., McArthur, R., Brudvig, G., Ghosh, D. K., and Stuehr, D. J. (1996) J. Biol. Chem. 271, 20594-20602
18. Salerno, J. C., Harris, D. E., Irizarry, K., Patel, B., Morales, A. J., Smith, S. M., Martásek, P., Roman, L. J., Masters, B. S. S., Jones, C. L., Weissman, B. A., Lane, P., Liu, Q., and Gross, S. S. (1997) J. Biol. Chem. 272, 29769-29777
19. Roman, L. J., Miller, R. T., de La Garza, M. A., Kim, J. J., and Masters, B. S. S. (2000) J. Biol. Chem. 275, 21914-21919
20. Roman, L. J., Martásek, P., Miller, R. T., Harris, D. E., de La Garza, M. A., Shea, T. M., Kim, J. J., and Masters, B. S. S. (2000) J. Biol. Chem. 275, 29225-29232
21. Nishida, C. R., and Ortiz de Montellano, P. R. (1999) J. Biol. Chem. 274, 14692-14698
22. Daff, S., Sagami, I., and Shimizu, T. (1999) J. Biol. Chem. 274, 30589-30595
23. Chen, P. F., and Wu, K. K. (2000) J. Biol. Chem. 275, 13155-13163
24. Montgomery, H. J., Romanov, V., and Guillemette, J. G. (2000) J. Biol. Chem. 275, 5052-5058
25. Nishida, C. R., and Ortiz de Montellano, P. R. (2001) J. Biol. Chem. 276, 20116-20124
26. Lane, P., and Gross, S. S. (2002) J. Biol. Chem. 277, 19087-19094
27. Roman, L. J., Sheta, E. A., Martásek, P., Gross, S. S., Liu, Q., and Masters, B. S. S. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8428-8432
28. Gegner, J. A., and Dahlquist, F. W. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 750-754
29. Zhang, M., and Vogel, H. J. (1994) J. Biol. Chem. 269, 981-985
30. Persechini, A., Gansz, K. J., and Paresi, R. J. (1996) Biochemistry 35, 224-228
31. Pietta, P., and Calatroni, A. (1982) J. Chromatogr. 229, 445-449
32. Munro, A. W., and Noble, M. A. (1999) in Methods in Molecular Biology: Flavoprotein Protocols (Chapman, S. K., and Reid, G. A., eds) pp. 1-25, Humana Press Inc., Totowa, NJ
33. Martásek, P., Miller, R. T., Roman, L. J., Shea, T., and Masters, B. S. S. (1999) Methods Enzymol. 301, 70-78
34. Garcin, E. D., Bruns, C. M., Lloyd, S. J., Hosfield, D. J., Tiso, M., Gachhui, R., Stuehr, D. J., Tainer, J. A., and Getzoff, E. D. (2004) J. Biol. Chem. 279, 37918-37927
35. Masters, B. S. S. (1994) Annu. Rev. Nutr. 14, 131-145
36. Matsuda, H., and Iyanagi, T. (1999) Biochim. Biophys. Acta 1473, 345-355
37. Miller, R. T., Martásek, P., Omura, T., and Masters, B. S. S. (1999) Biochem. Biophys. Res. Commun. 265, 184-188
38. Roman, L. J., McLain, J., and Masters, B. S. S. (2003) J. Biol. Chem. 278, 25700-25707
39. Panda, K., Ghosh, S., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 23349-23356
40. Zhang, M., Yuan, T., Aramini, J. M., and Vogel, H. J. (1995) J. Biol. Chem. 270, 20901-20907
41. Alexander, L. M., Hersh, L. B., and Masters, B. S. (1980) in Microsomes, Drug Oxidations, and Chemical Carcinogenesis (Coon, M. J., Conney, A. H., Estabrook, R. W., Gelboin, H. V., Gillette, J. R., and O'Brien, P. J., eds) pp. 285-288, Academic Press, New York
42. Vermilion, J. L., Ballou, D. P., Massey, V., and Coon, M. J. (1981) J. Biol. Chem. 256, 266-277
43. Noble, M. A., Munro, A. W., Rivers, S. L., Robledo, L., Daff, S. N., Yellowlees, L. J., Shimizu, T., Sagami, I., Guillemette, J. G., and Chapman, S. K. (1999) Biochemistry 38, 16413-16418
44. Tiso, M., Konas, D. W., Panda, K., Garcin, E. D., Sharma, M., Getzoff, E. D., and Stuehr, D. J. (2005) J. Biochem. (Tokyo) 280, 39208-39219
45. Linse, S., Helmersson, A., and Forsen, S. (1991) J. Biol. Chem. 266, 8050-8054
46. Persechini, A., McMillan, K., and Leakey, P. (1994) J. Biol. Chem. 269, 16148-16154
47. Persechini, A., Stemmer, P. M., and Ohashi, I. (1996) J. Biol. Chem. 271, 32217-32225
48. Su, Z., Blazing, M. A., Fan, D., and George, S. E. (1995) J. Biol. Chem. 270, 29117-29122
49. Gachhui, R., Abu-Soud, H. M., Ghosha, D. K., Presta, A., Blazing, M. A., Mayer, B., George, S. E., and Stuehr, D. J. (1998) J. Biol. Chem. 273, 5451-5454
50. Newman, E., Spratt, D. E., Mosher, J., Cheyne, B., Montgomery, H. J., Wilson, D. L., Weinberg, J. B., Smith, S. M., Salerno, J. C., Ghosh, D. K., and Guillemette, J. G. (2004) J. Biol. Chem. 279, 33547-33557
51. Zhang, J., Martásek, P., Paschke, R., Shea, T., Masters, B. S. S., and Kim, J. J. (2001) J. Biol. Chem. 276, 37506-37513
52. Jones, R. J., Smith, S. M., Gao, Y. T., DeMay, B. S., Mann, K. J., Salerno, K. M., and Salerno, J. C. (2004) J. Biol. Chem. 279, 36876-36883
53. Knudsen, G. M., Nishida, C. R., Mooney, S. D., and Ortiz de Montellano, P. R. (2003) J. Biol. Chem. 278, 31814-31824