Conformational dynamics and the energetics of protein-ligand interactions: Role of interdomain loop in human cytochrome P450 reductase

Biochemistry

Volumn 46, Issue 28, 2007, Pages 8244-8255

  Grunau, Alex ^a   Geraki, Kalotina ^b   Grossmann, J Günter ^b   Gutierrez, Aldo ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b SCIENCE AND TECHNOLOGY FACILITIES COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; CYTOCHROME P450 REDUCTASE; ENERGY PROPAGATION; SHAPE RECONSTRUCTION;

CALORIMETRY; LIGANDS; MUTAGENESIS; PROTEINS; SPECIFIC HEAT; X RAY SCATTERING;

BIOCHEMISTRY;

AB INITIO CALCULATION; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CALORIMETRY; DELETION MUTANT; DIMERIZATION; ELECTRON TRANSPORT; ENTHALPY; ENZYME MECHANISM; HUMAN; LIGAND BINDING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; THEORETICAL MODEL; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; CALORIMETRY; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; THERMODYNAMICS; X-RAY DIFFRACTION;

KOBUS;

EID: 34447566126     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700596s     Document Type: Article

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