Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 33, 2011, Pages 13486-13491

  Xia, Chuanwu ^a   Panda, Satya P ^b   Marohnic, Christopher C ^b,d   Martaśek, Pavel ^c   Masters, Bettie Sue ^b   Kim, Jung Ja P ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c CHARLES UNIVERSITY   (Czech Republic)

^d ABBOTT LABORATORIES   (United States)

Author keywords

Antley Bixler syndrome; Diflavin enzymes; Heme oxygenation; Protein folding; X ray crystallography

Indexed keywords

CYTOCHROME P450 REDUCTASE; MUTANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING;

FLAVIN-ADENINE DINUCLEOTIDE; HUMANS; MOLECULAR STRUCTURE; MUTATION, MISSENSE; NADPH-FERRIHEMOPROTEIN REDUCTASE; POLYMORPHISM, GENETIC; PROTEIN FOLDING; TRYPSIN;

EID: 80051958464     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1106632108     Document Type: Article

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