Thrombin Binding Aptamer, more than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications

Current Pharmaceutical Design

Volumn 18, Issue 14, 2012, Pages 2036-2047

  Aviñó, Anna ^a   Fàbrega, Carme ^a   Tintoré, María ^a   Eritja, Ramon ^a  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

Author keywords

Anticoagulant; Aptamer; DNA; G quadruplex; Oligonucleotide synthesis; TBA; Thrombin; Thrombin binding aptamer

Indexed keywords

ANTICOAGULANT AGENT; APTAMER; ARC 183; DNA; GUANINE QUADRUPLEX; METAL ION; NU172; NUCLEOSIDE; THIOGUANINE DERIVATIVE; THROMBIN; THROMBIN BINDING APTAMER; UNCLASSIFIED DRUG;

ANTICOAGULATION; CALORIMETRY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CLINICAL ASSESSMENT TOOL; CLINICAL TRIAL (TOPIC); CYCLIC POTENTIOMETRY; DNA MODIFICATION; ELECTROSPRAY; ENZYME BINDING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HYDROPHOBICITY; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTHROMBIN TIME; RECOGNITION; REVIEW; RNA FOLDING; STOICHIOMETRY; ULTRAVIOLET SPECTROSCOPY;

ANTICOAGULANTS; APTAMERS, NUCLEOTIDE; BIOSENSING TECHNIQUES; CLINICAL TRIALS AS TOPIC; G-QUADRUPLEXES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 84860203819     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799958387     Document Type: Review

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