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note
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3. Equal volumes of the ODN and the metal-salt solutions were mixed and then introduced into the ESI source with a syringe pump at 5 μL/min. For H/D exchange, 2.5 μM samples were used, and the sample solutions were sprayed at 1 μL/min. Experiments were in the MS/MS mode using "zero" for the activation amplitude and changing the activation time from 0.03 to 10 000 ms. Five scans were averaged at each time point, the averaged spectrum was smoothed, and the centroids of the peak distribution, which represented D uptake, were used for the modeling.
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