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Volumn 272, Issue 5, 1997, Pages 688-698

Oligonucleotide inhibitors of human thrombin that bind distinct epitopes

Author keywords

G quadruplex; Oligonucleotides; Photocrosslinking; SELEX; Thrombin

Indexed keywords

EPITOPE; FIBRIN; OLIGONUCLEOTIDE; THROMBIN; THROMBIN INHIBITOR;

EID: 0031563773     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1275     Document Type: Article
Times cited : (761)

References (33)
  • 1
    • 0002978084 scopus 로고
    • Linear amplification DNA sequencing
    • Adams S. M., Blakesley R. Linear amplification DNA sequencing. Focus. 13:1991;56-58.
    • (1991) Focus , vol.13 , pp. 56-58
    • Adams, S.M.1    Blakesley, R.2
  • 2
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock L. C., Griffin L. C., Latham J. A., Vermass E. H., Toole J. J. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature. 355:1992;564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermass, E.H.4    Toole, J.J.5
  • 3
    • 0024431034 scopus 로고
    • The refined 1.9 Å crystal structure of human α-thrombin: Interaction withD
    • Bode W., Mayr I., Baumann U., Huber R., Stone S. R., Hofsteenge J. The refined 1.9 Å crystal structure of human α-thrombin: interaction withD. EMBO J. 8:1989;3467-3475.
    • (1989) EMBO J. , vol.8 , pp. 3467-3475
    • Bode, W.1    Mayr, I.2    Baumann, U.3    Huber, R.4    Stone, S.R.5    Hofsteenge, J.6
  • 4
    • 0002987063 scopus 로고
    • X-ray crystal structures of human α-thrombin and of the human thrombin-hirudin complex
    • New York and London: Plenum Press
    • Bode W., Huber R., Rydel T. J., Tulinsky A. X-ray crystal structures of human α-thrombin and of the human thrombin-hirudin complex. Thrombin Structure and Function. 1992;Plenum Press, New York and London.
    • (1992) Thrombin Structure and Function
    • Bode, W.1    Huber, R.2    Rydel, T.J.3    Tulinsky, A.4
  • 5
    • 0029379551 scopus 로고
    • Let's get specific: The relationship between specificity and affinity
    • Eaton B. E., Gold L., Zichi D. A. Let's get specific: the relationship between specificity and affinity. Chem. Biol. 2:1995;633-638.
    • (1995) Chem. Biol. , vol.2 , pp. 633-638
    • Eaton, B.E.1    Gold, L.2    Zichi, D.A.3
  • 8
    • 0029031094 scopus 로고
    • Oligonucleotides as research, diagnostic, and therapeutic agents
    • Gold L. Oligonucleotides as research, diagnostic, and therapeutic agents. J. Biol. Chem. 270:1995;13581-13584.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13581-13584
    • Gold, L.1
  • 10
    • 0027361841 scopus 로고
    • High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding
    • Jellinek D., Lynott C. K., Rifkin D. B., Janjic N. High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding. Proc. Natl Acad. Sci. USA. 90:1993;11227-11231.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 11227-11231
    • Jellinek, D.1    Lynott, C.K.2    Rifkin, D.B.3    Janjic, N.4
  • 11
    • 0029980523 scopus 로고    scopus 로고
    • Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG)
    • Kelly J. A., Feigon J., Yeates T. O. Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG). J. Mol. Biol. 256:1996;417-422.
    • (1996) J. Mol. Biol. , vol.256 , pp. 417-422
    • Kelly, J.A.1    Feigon, J.2    Yeates, T.O.3
  • 15
    • 0027467617 scopus 로고
    • Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution
    • Macaya R. F., Schultze P., Smith F. W., Roe J. A., Feigon J. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc. Natl Acad. Sci. USA. 90:1993;3745-3749.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3745-3749
    • Macaya, R.F.1    Schultze, P.2    Smith, F.W.3    Roe, J.A.4    Feigon, J.5
  • 16
    • 0028950659 scopus 로고
    • Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs
    • Macaya R. F., Waldron J. A., Beutel B. A., Gao H., Joeston M. E., Yang M., Patel R., Bertelsen A. H., Cook A. G. Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs. Biochemistry. 34:1995;4478-4492.
    • (1995) Biochemistry , vol.34 , pp. 4478-4492
    • Macaya, R.F.1    Waldron, J.A.2    Beutel, B.A.3    Gao, H.4    Joeston, M.E.5    Yang, M.6    Patel, R.7    Bertelsen, A.H.8    Cook, A.G.9
  • 17
    • 0029912468 scopus 로고    scopus 로고
    • High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein
    • Meisenheimer K. M., Meisenheimer P. L., Willis M. C., Koch T. H. High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein. Nucl. Acids Res. 24:1996;981-982.
    • (1996) Nucl. Acids Res. , vol.24 , pp. 981-982
    • Meisenheimer, K.M.1    Meisenheimer, P.L.2    Willis, M.C.3    Koch, T.H.4
  • 21
    • 0028318093 scopus 로고
    • Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)
    • Schultze P., Macaya R. F., Feigon J. Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG). J. Mol. Biol. 235:1994;1532-1547.
    • (1994) J. Mol. Biol. , vol.235 , pp. 1532-1547
    • Schultze, P.1    Macaya, R.F.2    Feigon, J.3
  • 23
    • 0008180802 scopus 로고
    • Hirudin interactions with thrombin
    • L.J. Berliner. New York and London: Plenum Press
    • Stone S. R., Maraganore J. M. Hirudin interactions with thrombin. Berliner L. J. Thrombin Structure and Function. 1992;Plenum Press, New York and London.
    • (1992) Thrombin Structure and Function
    • Stone, S.R.1    Maraganore, J.M.2
  • 24
    • 0028912561 scopus 로고
    • The clot thickens: Clues provided by thrombin structure
    • Stubbs M. T., Bode W. The clot thickens: clues provided by thrombin structure. Trends Biochem. Sci. 20:1995;23-28.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 23-28
    • Stubbs, M.T.1    Bode, W.2
  • 25
    • 12444276102 scopus 로고
    • Crosslinking of an iodo-uridine-RNA hairpin to a single site on the human U1A N-terminal RNA binding domain
    • Stump W. T., Hall K. B. Crosslinking of an iodo-uridine-RNA hairpin to a single site on the human U1A N-terminal RNA binding domain. RNA. 1:1995;55-63.
    • (1995) RNA , vol.1 , pp. 55-63
    • Stump, W.T.1    Hall, K.B.2
  • 26
    • 0029131498 scopus 로고
    • Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin usingin vitro
    • Tsiang M., Gibbs C. S., Griffin L. C., Dunn K. E., Leung L. K. Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin usingin vitro. J. Biol Chem. 270:1995a;19370-19376.
    • (1995) J. Biol Chem. , vol.270 , pp. 19370-19376
    • Tsiang, M.1    Gibbs, C.S.2    Griffin, L.C.3    Dunn, K.E.4    Leung, L.K.5
  • 28
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C., Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science. 249:1990;505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 29
    • 0027380687 scopus 로고
    • A tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity
    • Wang K. Y., Krawczyx S. H., Bischofberger N., Swaminathan S., Bolton P. H. A tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity. Biochemistry. 32:1993a;11285-11292.
    • (1993) Biochemistry , vol.32 , pp. 11285-11292
    • Wang, K.Y.1    Krawczyx, S.H.2    Bischofberger, N.3    Swaminathan, S.4    Bolton, P.H.5
  • 30
    • 0027537022 scopus 로고
    • A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA
    • Wang K. Y., McCurdy S., Shea R. G., Swaminathan S., Bolton P. H. A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA. Biochemistry. 32:1993b;1899-1904.
    • (1993) Biochemistry , vol.32 , pp. 1899-1904
    • Wang, K.Y.1    McCurdy, S.2    Shea, R.G.3    Swaminathan, S.4    Bolton, P.H.5
  • 31
    • 0027717964 scopus 로고
    • Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins
    • Willis M. C., Hicke B. J., Uhlenbeck O. C., Cech T. R., Koch T. H. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. Science. 262:1993;1255-1257.
    • (1993) Science , vol.262 , pp. 1255-1257
    • Willis, M.C.1    Hicke, B.J.2    Uhlenbeck, O.C.3    Cech, T.R.4    Koch, T.H.5
  • 32
    • 0028606714 scopus 로고
    • An RNA-protein contact determined by 5-bromouridine substitution, photocrosslinking and sequencing
    • Willis M. C., LeCuyer K. A., Meisenheimer K. M., Uhlenbeck O. C., Koch T. H. An RNA-protein contact determined by 5-bromouridine substitution, photocrosslinking and sequencing. Nucl. Acids Res. 22:1994;4947-4952.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 4947-4952
    • Willis, M.C.1    LeCuyer, K.A.2    Meisenheimer, K.M.3    Uhlenbeck, O.C.4    Koch, T.H.5
  • 33
    • 0026464915 scopus 로고
    • Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite
    • Wu Q., Tsiang M., Sadler J. E. Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite. J. Biol. Chem. 267:1992;24408-24412.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24408-24412
    • Wu, Q.1    Tsiang, M.2    Sadler, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.